Compositions for lubricating skin during application of a fascia tissue treatment device, thereby reducing the appearance of cellulite in skin and methods of forming such compositions.

Disclosed is a method for reducing the appearance of a wrinkle on skin comprising topically applying to said wrinkle a composition that includes an effective amount of ornithine, retinol, Commiphora mukul resin or an extract thereof, and hyaluronic acid, wherein topical application of the composition reduces the appearance of said wrinkle within 120 seconds after application of the composition, and wherein topical application of said composition stimulates adipogenesis in said skin.

Disclosed is a method for reducing the appearance of a wrinkle on skin comprising topically applying to said wrinkle a composition that includes an effective amount of ornithine, retinol, Commiphora mukul resin or an extract thereof, and hyaluronic acid, wherein topical application of the composition reduces the appearance of said wrinkle within 120 seconds after application of the composition, and wherein topical application of said composition stimulates adipogenesis in said skin.

Contained herein are compositions, formulations, methods, and kits for treating regional fat deposits and fat-related conditions. Certain methods comprise administering tetradecyl sulfate, tetradecyl sulfate-like compounds, and pharmaceutically or cosmetically acceptable salts, solvates, prodrugs, or esters thereof and a liquid carrier.

Contained herein are compositions, formulations, methods, and kits for treating regional fat deposits and fat-related conditions. Certain methods comprise administering tetradecyl sulfate, tetradecyl sulfate-like compounds, and pharmaceutically or cosmetically acceptable salts, solvates, prodrugs, or esters thereof and a liquid carrier.

A skin cleansing composition having biodegradable abrasive particles, is provided. The abrasive particles have a mean Circularity of from about 0.10 to about 0.60 and a mean particle size as expressed by the area-equivalent diameter of about 500 m to about 2,000 m and a Biodegradable Rate of about 30% to about 100%. The composition has a structured surfactant phase or surfactant phase having a Yield Stress of about 1 Pa to about 100 Pa or a Yield Stress of about 0.1 Pa to about 10 Pa, respectively.

A skin cleansing composition having biodegradable abrasive particles, is provided. The abrasive particles have a mean Circularity of from about 0.10 to about 0.60 and a mean particle size as expressed by the area-equivalent diameter of about 500 m to about 2,000 m and a Biodegradable Rate of about 30% to about 100%. The composition has a structured surfactant phase or surfactant phase having a Yield Stress of about 1 Pa to about 100 Pa or a Yield Stress of about 0.1 Pa to about 10 Pa, respectively.

The present invention provides a topical composition for application to a keratinous tissue comprising a cosmetically or pharmaceutically acceptable carrier; one or more selected from potassium, zinc, calcium, rubidium disposed in the cosmetically or pharmaceutically acceptable carrier; and one or more peptides disposed in the cosmetically or pharmaceutically acceptable carrier.

Provided is an oxyntomodulin analogue. The analogue comprises GCGR and GLP-1R dual agonist activity, improved enzymolysis stability and biological activity, and no adverse reactions. The analogue can be used to prepare medication for treating hyperphagia, obesity and diabetes.

The invention relates to the cosmetic use of isoleucine N-hexadecanoyl of formula (I): CH.sub.3(CH.sub.2).sub.14C(O)NHCH(COOH)CH(CH.sub.3)CH.sub.2CH.sub.3 (I) as a volumizing agent and/or as a plumping agent for human skin. The invention also relates to a cosmetic treatment method for obtaining a volumizing and/or plumping effect of the skin of a part of the human body selected from among the breasts, face, cheeks, buttocks and eyelids.