Compositions and topical formulations comprising a PPAR agonist complex comprising glyceryl linoleate, glyceryl linolenate, xymenynic acid, and Pterocarpus marsupium bark extract are described herein. Methods of inducing skin barrier repair, increasing the biosynthesis of barrier lipids and proteins in the skin, stimulating hair growth, treating acne and combinations thereof utilizing the composition and topical formulations are also provided herein.

Compositions and topical formulations comprising a PPAR agonist complex comprising glyceryl linoleate, glyceryl linolenate, xymenynic acid, and Pterocarpus marsupium bark extract are described herein. Methods of inducing skin barrier repair, increasing the biosynthesis of barrier lipids and proteins in the skin, stimulating hair growth, treating acne and combinations thereof utilizing the composition and topical formulations are also provided herein.

A physically stable skin care serum emulsion composition with a continuous phase and a dispersed phase. The continuous phase can include from about 0.5% to about 1.5% sodium hyaluronate with a weight average molecular weight from about 500,000 to about 1,000,000 Da according to the European Pharmacopoeia Method. The continuous phase can also include a thickening agent that includes polyacrylamide polymers and copolymers. The dispersed phase can include silicone. The composition can have an average viscosity from about 4,000 cP to about 25,000 cP and can be stored and dispense via a dropper package.

A physically stable skin care composition with a continuous phase and a dispersed phase and a method for making the same. The continuous phase can include from about 0.5% to about 1.5% sodium hyaluronate with a weight average molecular weight from about 500,000 to about 1,000,000 Da according to the European Pharmacopoeia Method. The continuous phase can also include at least two thickening agents that can includes polyacrylamide polymers and copolymers and a carboxylic acid polymer. The dispersed phase can include silicone. The composition can have an average viscosity greater than 25,000 cP and the sodium hyaluronate can be fully hydrated.

Preparations and formulations capable of crossing and incorporating into a membrane of a cell or an organelle or an exosome are described. Methods of treatments utilizing the preparations and formulations are also described.

The present invention relates to a cosmetic composition in the form of an oil-in-water emulsion comprising: (i) at least one C.sub.16-C.sub.30 fatty alcohol; (ii) at least one anionic surfactant of general formula (I): RCOY(CH.sub.2)nSO.sub.3M; (iii) at least one oil; (iv) at least one wax, and (v) at least one hydrophilic solvent, the weight ratio of anionic surfactant(s) of general formula (I)/fatty alcohol(s) ranging from 1/5 to 1/3, said composition comprising from 1% to 10% by weight of wax(es) relative to the total weight of the composition. The present invention also relates to a process for preparing said composition and a cosmetic makeup and/or care process.

The invention relates to a cosmetic active ingredient comprising at least one Metschnikowia reukaufii extract, and the use of same for the cosmetic treatment of the skin, in particular for improving the radiance of the complexion by acting on the skin microbiota. The active ingredient is effective on mature skin. The invention also concerns compositions comprising the cosmetic active ingredient and a cosmetic method for treating the skin using these compositions.

The invention relates to a cosmetic active ingredient comprising at least one Metschnikowia reukaufii extract, and the use of same for the cosmetic treatment of the skin, in particular for improving the radiance of the complexion by acting on the skin microbiota. The active ingredient is effective on mature skin. The invention also concerns compositions comprising the cosmetic active ingredient and a cosmetic method for treating the skin using these compositions.

The disclosure relates to the establishment of a cell line having immune tolerance property using an optimal temperature profiling technique under a human body-like environment, and use thereof. The stem cell line exhibits immune tolerance property as they consecutively secret and express HLA-G proteins, and the culture medium of the stem cells contains a large amount of proteins capable of recovering various physiological functions and extracellular vesicles, and thus, the novel cell line or a culture medium thereof can be effectively used in various industries such as medicines and cosmetics.

The present invention relates to a medium composition for cell proliferation, skin regeneration, and wrinkle improvement that contains a conditioned medium of pluripotent stem cells (PSCs), neural stem cells (NSCs), and embryonic fibroblasts (FBs) as cells isolated from avian eggs as an active ingredient. Specifically, the conditioned medium of egg cells can fundamentally block contamination due to the use of animal serums, exhibits a proliferation effect of various cells containing human stem cells and skin cells without the possibility of transmission by infectious agents between heterogeneous species due to the use of support cells, and exhibits significant skin regeneration or wrinkle improvement effects, and thus the conditioned medium of egg cells can be usefully used for a medium composition for cell proliferation and a cosmetic composition for skin regeneration or wrinkle improvement.