A method of treating a spinal disk according to the present invention can include inserting an alloplastic bulking agent into the spinal disk to treat the defect. The alloplastic bulking agent has a plurality of microparticles and a suspending agent comprising hyaluronic acid. The bulking agent results in at least one of sealing the defect, increasing a pressure of the disk, increasing a height of the disk, improving stability of the disk and improving structural integrity of the disk.

A method of treating a spinal disk according to the present invention can include inserting an alloplastic bulking agent into the spinal disk to treat the defect. The alloplastic bulking agent has a plurality of microparticles and a suspending agent comprising hyaluronic acid. The bulking agent results in at least one of sealing the defect, increasing a pressure of the disk, increasing a height of the disk, improving stability of the disk and improving structural integrity of the disk.

Method and apparatus for personal isolation and/or protection are disclosed. In one variation, the system may include a passive filtration component having a mask configured for positioning over a mouth and/or nose of a user, wherein the mask has at least one portion configured to filter air passing through the at least one portion. An active filtration component having a fan may be included, wherein the active filtration component is configured to filter air entering or exiting the active filtration component via the fan, and a hose fluidly coupled between the passive filtration component and the active filtration component such that the active filtration component is remote from a face of the user when in use.

Method and apparatus for personal isolation and/or protection are disclosed. In one variation, the system may include a passive filtration component having a mask configured for positioning over a mouth and/or nose of a user, wherein the mask has at least one portion configured to filter air passing through the at least one portion. An active filtration component having a fan may be included, wherein the active filtration component is configured to filter air entering or exiting the active filtration component via the fan, and a hose fluidly coupled between the passive filtration component and the active filtration component such that the active filtration component is remote from a face of the user when in use.

A respiratory protection composite facepiece is disclosed and includes a polymeric rigid facepiece body portion having a first surface and a second surface and a silicone sealing facepiece element chemically bonded at least one of the first surface or the second surface. The first and second surfaces can be opposing major surfaces. A second silicone element is chemically bonded to at least one of the first surface or the second surface. Methods of making the same are also disclosed.

A pulse modulated oxygen dispensing and pressurization system provides a variable range of controlled oxygen bolus to an enclosed breathing environment supporting and maintaining required pressure conditions in accordance with desired flow demand. As oxygen is consumed by the user from within the enclosed breathing environment, the exhaled gases and moisture are conditioned or vented to acceptable levels by additional systems associated with the environment. These additional systems cause an ongoing need to replenish the oxygen within the environment and maintain the required partial pressure of oxygen. Specific to one of a plurality of modes of operation, the system responds to changes in regulated output pressure by delivering a precisely metered periodic bolus volume of oxygen to support a requirement of the environment volume. The bolus is variable based on a plurality of factors to increase and decrease changes in rates of flow required to maintain regulated pressure.

An airway assist device and methods of making and using an airway assist device to assist in opening an airway or removing fluid or material obstructing an airway of a subject.

An airway assist device and methods of making and using an airway assist device to assist in opening an airway or removing fluid or material obstructing an airway of a subject.

A bidirectional reusable filtering face mask is described that includes an anatomical base provided with means to promote adherence to the face and pass-through elements for closure by means of ties; a first filtering chamber used to prevent respiratory droplets from spreading and obtained by fixing a removable disposable filter on the outer side of the anatomical base; a second filtering chamber comprising a removable dome with a recess in its apical part adapted to accommodate a main removable disposable filter, where the filter is secured to the recess by means of a protective grid; and means for assembling the components of the second filtering chamber with the first filtering chamber.

A rapidly deployable, pressure sealed, cough and sneeze aerosol, containment apparatus and a system to virtually eradicate the cold, the flu, and Covid-19. A face mask having a rigid first section configured to hold a filter and a pliable second section configured to fit on a person's face; a face mask seal formed on an edge of the pliable second section of the face mask; a curved surface on the face mask seal configured to fold inward to form a seal on the person's face when pressed on the person's face.