Described herein are pharmaceutical compositions comprising cannabinoids. In some embodiments, such compositions are useful for the treatment of inflammatory or autoimmnune diseases or disorders. Further provided herein are pharmaceutical compositions comprising combinations of cannabinoids possessing entourage effects.

Provided is a modified Cannabis plant exhibiting reduced volatile organic compounds (VOCs) emission. The modified Cannabis plant includes at least one targeted gene modification conferring reduced expression or silencing of at least one gene involved in a terpene biosynthesis pathway. Further provided are methods and uses concerning the aforementioned modified Cannabis plant.

Provided is a modified Cannabis plant exhibiting reduced volatile organic compounds (VOCs) emission. The modified Cannabis plant includes at least one targeted gene modification conferring reduced expression or silencing of at least one gene involved in a terpene biosynthesis pathway. Further provided are methods and uses concerning the aforementioned modified Cannabis plant.

The D-Leefer, Bucked Cannabis Flower and Biomass Refinement Apparatus and Kief Extractor System is a device for separating dried leaves from female flowers or for separating and refining a plurality of leaves and a plurality of kief from a biomass comprising a hopper having a tray in the form a U-shaped channel having a plurality of openings positioned along its bottom, an auger positioned within said tray having a auger drive motor to spin said auger about its length, a mesh positioned along the bottom half of said auger, a plurality of collection hoods positioned along the bottom side of said U-shaped tray under said mesh each having a vacuum connection, and a plurality of vacuum devices each having a collection container and a hose attached to said vacuum connections.

The D-Leefer, Bucked Cannabis Flower and Biomass Refinement Apparatus and Kief Extractor System is a device for separating dried leaves from female flowers or for separating and refining a plurality of leaves and a plurality of kief from a biomass comprising a hopper having a tray in the form a U-shaped channel having a plurality of openings positioned along its bottom, an auger positioned within said tray having a auger drive motor to spin said auger about its length, a mesh positioned along the bottom half of said auger, a plurality of collection hoods positioned along the bottom side of said U-shaped tray under said mesh each having a vacuum connection, and a plurality of vacuum devices each having a collection container and a hose attached to said vacuum connections.

The present invention discloses cannabis hybrid plant varieties designated as AT11033FL-1047, AT11043FL-1063, AT11053FL-1069, AT11063FL-1080, and AT11073FL-1081, and the inbred parent lines AT15023PS-17-2-9-15, AT15003P5-17-2-5-29, AT15013P5-18-2-2-3, AT15053P5-18-3-25-10, AT15043PS-18-3-28-19, and AT15033PS-19-1-1-11 used to produce the hybrids. The cultivars are feminized, autoflowering, cannabis varieties. Additional embodiments of the invention further provides tissues cultures, seeds, protoplasts, plant cells, and hybrids of the described cultivars.

The present invention discloses cannabis hybrid plant varieties designated as AT11033FL-1047, AT11043FL-1063, AT11053FL-1069, AT11063FL-1080, and AT11073FL-1081, and the inbred parent lines AT15023PS-17-2-9-15, AT15003P5-17-2-5-29, AT15013P5-18-2-2-3, AT15053P5-18-3-25-10, AT15043PS-18-3-28-19, and AT15033PS-19-1-1-11 used to produce the hybrids. The cultivars are feminized, autoflowering, cannabis varieties. Additional embodiments of the invention further provides tissues cultures, seeds, protoplasts, plant cells, and hybrids of the described cultivars.

The present invention relates to a method for producing sterile flowering biomass, the method comprising: a) inoculating a temporary liquid immersion culture system containing a sterile culture medium containing at least one cytokinin with sterile plant material, b) growing leafy biomass, and c) inducing and maturing flower tissues from the leafy biomass, wherein flowering is induced by reducing the duration and/or frequency of the immersion of the plant material in the culture medium in step c) compared to step b). It further relates to a method for producing a component present in flowering biomass, using sterile flowering biomass obtained using the aforementioned method according to the invention.

The unique annual herbaceous Cannabis plant variety ‘OT-1’ is provided. The variety is a selection intended for use as medical oil, and medicinal herb for sale in Cannabis dispensaries and as a home garden plant.

The present disclosure relates generally to targeted gene editing constructs, including methods of designing a DNA-recognition moiety for modulation of gene expression in plants, DNA-recognition moieties, gene editing constructs, methods for the modulation of gene expression in plants using gene editing constructs, and plants or regenerable plant cells produced therefrom.