A generating method for generating one of mist and fine-bubbles or fine-bubbles is provided. The generating method includes arranging a piezoelectric substrate equipped thereon with an excitation source in a liquid, generating a flow of the liquid using a liquid flow generator that generates the flow of the liquid relative to the piezoelectric substrate, exciting a surface acoustic wave on the excitation source, propagating the excited surface acoustic wave so as to generate mist on a gas side and to generate fine-bubbles on a liquid side of the piezoelectric substrate, carrying the generated fine-bubbles away from the piezoelectric substrate with the generated flow of the liquid, and drawing the liquid containing the fine-bubbles from a liquid container which contains the liquid.

The present invention provides a liquid treatment apparatus with ring vortex processor for treating a liquid medium and, more particularly, to an apparatus and method for enhancing chemical reactions occurring in processes utilizing hydrodynamic cavitation. The liquid treatment apparatus with ring vortex processor efficiently utilizes fluid energy for cavitation bubble formation, maximizes the temperatures and pressures generated during bubble collapse, and minimizes damage caused by erosion.

Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.

Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.

A system for continuously processing materials. The system includes a continuous process vessel (CPV) and an acoustic agitator coupled to the CPV and configured to agitate the CPV along an oscillation axis. The CPV includes at least one inlet configured for introducing first and second process ingredients into an upper portion, with respect to the oscillation axis, of the CPV. The CPV includes an outlet for discharging the product of mixing the ingredients from a lower portion, with respect to the oscillation axis, of the CPV. The CPV includes a plurality of mixing regions, each defined by an upper angled surface and a lower angled surface. The surfaces of each mixing region are angled such that the distance between the surfaces is greater towards the upper portion of the continuous process vessel than the distance between the surfaces towards the lower portion of the continuous process vessel.

An apparatus for disintegration (or mixing) of a solid in a receptacle containing liquid, has a control unit and an ultrasound transducer generating ultrasonic energy under control of the control unit. An annular coupling element in communication with the ultrasound transducer is adapted to receive the receptacle. Ultrasonic energy is transferred to the receptacle contents through the annular coupling element. In use, the ultrasonic energy transferred to the receptacle contents causes disintegration of the solid into the liquid. A method for disintegration of a solid in a receptacle is also described.

An apparatus for preparing compound dispersoids of hydrophobic nanoparticles and surfactants, comprises a water supply pipeline, a compounding mixing pipeline and an aggregating pipeline; the compounding mixing pipeline comprises an ultrasonic dispersion instrument and a liquid storage tank connected in series into a loop, and a second plunger pump allowing unidirectional circulation of materials is arranged between the ultrasonic dispersion instrument and the liquid storage tank; the water supply pipeline is connected to the top of the ultrasonic dispersion instrument; and the aggregating pipeline is connected to a discharge end of the liquid storage tank.

Aspects of the present disclosure include methods of producing a cellular suspension from a tissue sample by applying resonant acoustic energy to a container comprising the tissue sample in a manner sufficient to produce a cellular suspension from the tissue sample. Resonant acoustic mixers and kits for use in producing a cellular suspension from a tissue sample are also provided.

Method and apparatus for controlling acoustic treatment of a sample to mediate a tagmentation process used on double stranded DNA.

Control over the wastewater purification can be achieved through controlling delivery of gas-dispersion return sludge solely to an aerobic reaction vessel. The gas-dispersion return sludge is created using pure oxygen or oxygen containing trace amounts of ozone as a reactive gas, which is blended with return sludge to create a mixture of gas and liquid, which is pressurized with an atomizer pump, and then at a pressure of not more than approximately 5.5 MPa, the mixture is passed through an atomizer which uses cavitation or ultrasound at a frequency of less than 12,000 KHz to instantly render the reactive gas in the mixture to an ultra-fine bubble state. A portion of the gas is placed into a dissolved state, reaching a state of supersaturation with a high DO value of 20-40 mg/l, and causing the remaining ultra-fine bubbles to create an ultra-fine bubble condition.