A device for mixing powders by cryogenic fluid, characterised in that it comprises at least: a chamber for mixing powders, comprising a cryogenic fluid; a chamber for supplying powders in order to allow the powders to be introduced into the mixing chamber; means for agitation in the mixing chamber so as to allow the mixing of the powders placed in suspension in the cryogenic fluid.

A device for mixing powders by a cryogenic fluid, characterised in that it comprises: a chamber for mixing the powders, comprising a cryogenic fluid, provided with means for forming a fluidised powder bed; a chamber for supplying powders in order to allow the powders to be introduced into the mixing chamber; a chamber for supplying cryogenic fluid in order to allow the cryogenic fluid to be introduced into the mixing chamber; a system for generating vibrations in the fluidised powder bed; and a system for controlling the system for generating vibrations.

Method and apparatus for controlling acoustic treatment of a sample to mediate a tagmentation process used on double stranded DNA.

A process for extracting carbohydrates from biomass and creating bioalcohol from the extracted carbohydrates. Subjecting the biomass to acid or alkali hydrolysis in a first hydrodynamic cavitation process. Filtering the first cavitated biomass to separate a first filtrate containing extracted carbohydrates. Fermenting the first filtrate to create a bioalcohol and separating the bioalcohol by distillation or similar process. Subjecting the biomass to enzymatic hydrolysis in a second hydrodynamic cavitation process. Filtering the second cavitated biomass to separate a second filtrate containing extracted carbohydrates. Fermenting the second filtrate to create a bioalcohol and separating the bioalcohol by distillation or similar process. The first and second filtrates may be combined and fermented in a single step.

A system and a method that utilizes wet proppants when creating fracturing fluid by receiving wet fracturing sand at a surge tank, vibrating the wet fracturing sand located within the surge tank, liquefying the wet fracturing sand within the surge tank based on the vibration, and metering the liquefied wet fracturing sand from the surge tank to a blending tub.

An apparatus for preparing compound dispersoids of hydrophobic nanoparticles and surfactants, comprises a water supply pipeline, a compounding mixing pipeline and an aggregating pipeline; the compounding mixing pipeline comprises an ultrasonic dispersion instrument and a liquid storage tank connected in series into a loop, and a second plunger pump allowing unidirectional circulation of materials is arranged between the ultrasonic dispersion instrument and the liquid storage tank; the water supply pipeline is connected to the top of the ultrasonic dispersion instrument; and the aggregating pipeline is connected to a discharge end of the liquid storage tank.

Gas-filled microbubbles can be synthesized using a continuous flow chamber and a sonicator. The resulting microbubble solution can be size-sorted for a particular application, such as injection into a patient for gas delivery thereto. The microbubble solution may be concentrated to have greater than 50% volume gas while maintaining microbubble sizes below 10 m. Control of the microbubble generation process can yield highly stable microbubbles. The microbubbles may retain over half of their original gas payload for over three weeks while exhibiting minimal change in microbubble size. The systems, methods, and devices described herein thus allow for continuous or batch-wise continuous production of gas-filled microbubbles that readily release their gas payload when introduced into an under-saturated or de-saturated solution.

Disclosed is an apparatus and method for providing asymmetric oscillations to a container. The container may include a fluid, a particle, and/or a gas. A vibration driver attached to the container provides asymmetric oscillations. A controller connected to the vibration driver controls an amplitude, frequency, and shape of the asymmetric oscillations. An amplifier amplifies the asymmetric oscillations in response to the controller. A sensor disposed on the vibration driver provides feedback to the controller.

Disclosed is an apparatus and method for providing asymmetric oscillations to a container. The container may include a fluid, a particle, and/or a gas. A vibration driver attached to the container provides asymmetric oscillations. A controller connected to the vibration driver controls an amplitude, frequency, and shape of the asymmetric oscillations. An amplifier amplifies the asymmetric oscillations in response to the controller. A sensor disposed on the vibration driver provides feedback to the controller.

A process for acoustically mixing a bulk drug substance involves the application of acoustic energy to drive an accelerative force in a mixing vessel containing the drug substance. The drug substance may be, for example, Elagolix.