A vacuum mixing device or system mixes polymethylmethacrylate bone cement from a monomer liquid and a cement powder. The device or system comprising at least one cartridge comprising an evacuable interior for mixing of the bone cement, a mixing device for mixing the content in the interior of the at least one cartridge, a receptacle for receiving a separate container containing the monomer liquid or comprising an integrated container containing the monomer liquid, an opening device, which is arranged in the region of the receptacle in a manner movable relative to the receptacle so that, by moving the opening device, a separate container arranged in the receptacle is openable by means of the opening device, or the opening device is arranged in the region of the integrated container in a manner movable relative to the integrated container so that, by moving the opening device, the integrated container is openable by means of the opening device, a vacuum pump, in which a movable vacuum plunger for generating a negative pressure is arranged and delimits a vacuum pump chamber of the vacuum pump, a pressure pump, in which a movable pump plunger for conveying a liquid is arranged and delimits a pressure pump chamber of the pressure pump, a connection line, and a fluid connection. The device or system further comprises an operating element that is operatable from outside, wherein, by means of the operating element, the vacuum plunger in the vacuum pump is movable manually, the pump plunger in the pressure pump is movable manually, the opening device is movable manually relative to the receptacle or relative to the integrated container, and the mixing device is movable manually in the interior of the cartridge.

Device for the mixing of polymethylmethacrylate bone cement and for storing a monomer liquid and a cement powder as starting components of the bone cement, comprising a cartridge having an internal space closed on one side by a mobile dispensing plunger; a monomer container for a monomer liquid and/or a connector for attachment of a monomer container which can be opened in the device so that the monomer liquid flows from the monomer container into the device; and a connecting conduit through which the monomer liquid can be guided into the internal space of the cartridge; having a pumping plunger that can be shifted axially in the hollow cylinder arranged in the hollow cylinder, which can be used to push monomer liquid from the hollow cylinder through the connecting conduit into the internal space of the cartridge by actuating the pumping plunger.

A method and high-pressure mixing device for co-injection of polymeric reactive components, in particular for polyurethane and epoxy mixtures. The polymeric components are supplied in a common pressure chamber where they flow at a same pressure and in an unmixed state into a forwardly converging fore portion of the pressure chamber, and through a settable co-injection orifice to be co-injected, in the unmixed state, into a mixing chamber transversely oriented to the pressure chamber. The settable co-injection orifice consists in an elongated restriction that longitudinally extends on a side wall of the mixing chamber orthogonally oriented to an intersecting the forwardly converging fore portion of the pressure chamber; a first cleaning member and a second cleaning member are sequentially reciprocable in the pressure chamber to eject the remaining unmixed polymeric components, respectively in the mixing chamber to eject the remaining mixture, and stop elements are provided to set an open section of the elongated restriction, by adjustably stopping the fore end of the cleaning member for the mixing chamber, in respect to the same elongated restriction of the co-injection orifice.

A vacuum mixing device for mixing PMMA bone cement from a monomer liquid and a cement powder, the vacuum mixing device comprising at least one cartridge comprising an evacuable interior for mixing of the bone cement, a mixing device for mixing the content in the interior of the at least one cartridge, which is arranged movably in the interior, a receptacle for receiving a separate container containing the monomer liquid or comprising an integrated container containing the monomer liquid, an opening device, which is arranged in the region of the receptacle in a manner movable relative to the receptacle so that, by moving the opening device, a separate container arranged in the receptacle is openable by means of the opening device, or the opening device is arranged in the region of the integrated container in a manner movable relative to the integrated container so that, by moving the opening device, the integrated container is openable by means of the opening device, a pump, in which a movable plunger for generating a negative pressure is arranged and delimits a pump chamber of the pump, and a connection line, which connects the interior of the at least one cartridge to the pump chamber of the pump, wherein the vacuum mixing system comprises an operating element that is operatable from outside, wherein the plunger in the pump is movable manually by means of the operating element, and wherein the opening device is movable relative to the receptacle or relative to the integrated container by means of the same operating element, and the mixing device in the interior of the cartridge is movable by means of the same operating element in order to mix the content in the interior of the cartridge.

A bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder on the coherent mass. In some embodiments, a method of implanting a bone material is provided, the method comprising contacting the bone material with a liquid, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass; molding the bone material into a shape to implant the bone material; and implanting the bone material at the target tissue site.

A pug mill having a housing and a cantilevered shaft extending through the housing includes, in seriatim, a vacuum chamber, a wall, a mixing chamber and a reduction cone. A communication port about the shaft is positioned in the wall between the vacuum chamber and the mixing chamber. Vacuum can be maintained within the mixing chamber by air passing through the port. An auger associated with the shaft forces clay toward the reduction cone. This creates a seal for maintaining vacuum within the mixing chamber and extrudes cylindrical blocks of conditioned clay without significant air bubbles. A deflection plate rotating with the shaft and a spiral element about the shaft keep the communication port clear. The shaft is eccentrically mounted. The dividing wall is removable.

A container for bone cement includes a first member defining a chamber, which contains a first ingredient. The chamber also includes a second member movably coupled to the first member. The second member includes a mixing device that is movably disposed within the first chamber, and the second member defines a second chamber containing a second ingredient. The container additional includes an opening device that selectively opens the second chamber and allows the second ingredient to enter from the second chamber into the first chamber. The mixing device is movable within the first chamber to promote mixing of the first ingredient and the second ingredient to prepare the bone cement. A corresponding method of preparing bone cement also disclosed.

Systems, apparatus, and articles of manufacture for stand-alone chemical dispensers are provided.

A mixing machine 1 comprising a mixing head 3 having element(s) for connecting to a receptacle to form a mixing container. The mixing head 3 is pivotably supported in a frame 2 such that the mixing container can pivot for the mixing process. The mixing head 3 has at least one rotationally driven mixing tool whose drive shaft 23 extends through the wall of the mixing head 3. The mixing head 3 has a double wall with a perforated inner wall 8. The perforations form a fluid path from the chamber surrounded by the inner wall 8 to the intermediate wall chamber 10. The intermediate wall chamber 10 is connected to a pressure adjustment device for adjusting the pressure. A flexible liner 15 is arranged in the mixing head 3 on its inner surface, which liner 15 can be fixed to the inner wall 8 of the mixing head by applying a vacuum.

A bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder on the coherent mass. In some embodiments, a method of implanting a bone material is provided, the method comprising contacting the bone material with a liquid, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass; molding the bone material into a shape to implant the bone material; and implanting the bone material at the target tissue site.