B01F3/22

MINIATURISED DEVICE FOR AUTOMATED MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS, AND ASSOCIATED METHOD
20210308642 · 2021-10-07 · ·

The present invention relates to a device (60) for manufacturing pharmaceutical compositions, comprising: a support (62); a mixing container (16); a plurality of reservoirs (18, 20) containing starting materials for the composition of a medicament; at least one dispensing device (64, 66) that is designed to dispense an amount of a starting material into the mixing container, wherein the dispensing device is assembled, or is designed to be assembled, with a reservoir; a stirring device (68) that is able to stir the mixing container and/or the contents of the mixing container; and an electronic module (74) for controlling the at least one dispensing device.

Ultrafine bubble generating method, ultrafine bubble generating apparatus, and ultrafine bubble-containing liquid

Provided is an UFB generating apparatus and an UFB generating method capable of efficiently generating an UFB-containing liquid with high purity. To this end, the ultrafine bubble generating apparatus includes a pre-processing unit that performs predetermined pre-processing on a liquid W and a generating unit that generates ultrafine bubbles in the liquid on which the pre-processing is performed. The generating unit generates the ultrafine bubbles by causing a heating element, which is provided in the liquid on which the pre-processing is performed, to generate heat to generate film boiling on an interface between the liquid and the heating element.

Manufacturing of bupivacaine multivesicular liposomes

Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.

METHOD FOR PRODUCING EMULSIONS AND AQUEOUS POLYISOBUTENE EMULSION
20210340335 · 2021-11-04 ·

The current invention concerns a method for preparing an emulsion comprising the steps: mixing a first phase and a second phase in a layer multiplier to produce a multilayered fluid structure, and collapsing said multilayered fluid structure, thereby dispersing the second phase in the first phase creating an emulsion. The current invention relates to a method for producing dispersions. The current invention also concerns the emulsions produced by said method. The current method also relates to polymer emulsions, particularly polyisobutene emulsions with a high content of polyisobutene.

Precise modifying method for fine particle dispersion liquid
11111145 · 2021-09-07 · ·

A method for modifying a fine particle dispersion liquid with which dispersibility and dispersion stability can be improved includes performing filtration to remove impurities in a dispersion liquid using a dispersion liquid modifying device provided with a removal unit that uses a filtration membrane. The quantity of impurities is reduced from a first region until said quantity reaches a second pH-dependent region. In the second pH-dependent region, the dispersibility of the fine particles in the dispersion liquid is in a range in which the dispersibility depends more on a change in dispersion liquid pH than on a change in the quantity of impurities in the dispersion liquid. With the quantity of impurities reduced to the second pH-dependent region, the dispersibility of the fine particles is controlled by adjusting the pH of the fine particle dispersion liquid.

Method of Producing Tobacco Mousse

Methods of forming a foam including a tobacco ingredient containing agent and/or an inhalable agent, an aerosol forming agent, a foam stabilizing agent, and a foam forming agent are provided, along with a foam produced by the methods, and foams with a certain aeration, for example of at least 4 vol. % based on the total volume of the foam.

AGRICULTURAL SAMPLING SYSTEM AND RELATED METHODS

An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (i.e. mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The sample preparation and chemical analysis subsystems can be used to analyze soil, vegetation, and/or manure samples.

Automated method and apparatus for preparing bioprocess solutions

An automated method includes providing a dry ingredient to be reconstituted into a liquid bioprocess solution and controlling, by a processing circuit, all automated system including at least one mixing chamber, an array of tubing for fluid flow within the system, and a plurality of valves provided within the tubing, to automatically prepare the liquid bioprocess solution from the dry ingredient. Controlling the auto system may include performing a series of sequential mixing steps, the series of sequential mixing steps causing the preparation of the liquid bioprocess solution. The method mixing include taking one or more measurements during the preparation of the liquid bioprocess solution, wherein each step is triggered by at least one of a measurement decreasing below, equaling, or exceeding a measurement threshold. Each step may also include opening or closing, by the processing circuit, at least one of the plurality of valves.

GAS SOLUTION MANUFACTURING DEVICE
20210245115 · 2021-08-12 ·

A gas solution manufacturing device 1 includes a gas supply line 2 configured to supply a gas as a raw material of a gas solution, a liquid supply line 3 configured to supply a liquid as a raw material of the gas solution, a gas solution production unit 4 configured to mix the gas and the liquid together to produce the gas solution, a gas-liquid separation unit 5 configured to perform gas-liquid separation of the produced gas solution into a supplied liquid to be supplied to a use point and a discharged gas to be discharged through an exhaust port, and a gas dissolving unit 6 provided in the liquid supply line 4 and configured to dissolve the discharged gas resulting from the gas-liquid separation in the liquid. The gas dissolving unit 6 is configured with a hollow fiber membrane configured with a gas permeable membrane.

UFB-CONTAINING LIQUID PRODUCTION APPARATUS AND UFB-CONTAINING LIQUID PRODUCTION METHOD

Provided is a UFB-containing liquid production apparatus that can efficiently produce a UFB-containing liquid with a UFB generation unit. The UFB-containing liquid production apparatus includes: a gas dissolution unit that produces a gas-dissolved liquid by dissolving a gas into a liquid supplied from a liquid supply unit; a UFB generation unit that generates UFBs in the flowing-in gas-dissolved liquid; and a circulation path that supplies the gas-dissolved liquid to the UFB generation unit and supplies a UFB-containing liquid produced by the UFB generation unit to the liquid supply unit. In the circulation path, there is provided a micro-bubble reduction unit that reduces an amount of micro-bubbles contained in the gas-dissolved liquid to flow into the UFB generation unit.