B01F3/22

ULTRAFINE BUBBLE-CONTAINING LIQUID PRODUCING APPARATUS AND ULTRAFINE BUBBLE-CONTAINING LIQUID PRODUCING METHOD

The present invention provides an ultrafine bubble-containing liquid producing apparatus capable of reducing the possibility of intermitting supply of a UFB-containing liquid. An ultrafine bubble-containing liquid producing apparatus includes producing units that produce an ultrafine bubble-containing liquid containing ultrafine bubbles by using a liquid supplied from a liquid introducing unit and deliver the produced ultrafine bubble-containing liquid to a liquid delivering unit. The producing units include a plurality of ultrafine bubble generating units capable of operating independently. Each of the plurality of ultrafine bubble generating units is provided to be capable of independently switching between communicating with and being disconnected from the liquid introducing unit and the liquid delivering unit.

METHODS OF SUPERCOOLING AQUEOUS SAMPLES
20210039057 · 2021-02-11 ·

This disclosure relates to methods of super-cooling of aqueous samples with or without biological samples. The methods involve, e.g., providing a container comprising the aqueous sample; applying an immiscible liquid phase of sufficient thickness to separate the aqueous sample from air; and cooling the aqueous sample to a temperature that is below 0 C.

Organic material purification composition and method of purifying organic materials using the same

An organic material purification composition, a mixed composition, and a method of purifying an organic material, the organic material purification composition including an ionic liquid in which a cation and an anion are combined; and an organic solvent, wherein the organic solvent includes an alcohol or a ketone.

METHOD FOR PREPARING LIPOSOME COMPRISING ULTRASOUND REACTIVE MICROBUBBLE FOR DRUG DELIVERY AND LIPOSOME USING SAME
20210015751 · 2021-01-21 ·

Provided are a method for preparing liposomes comprising ultrasound reactive microbubbles for drug delivery, comprising (a) a step of producing ultrasound reactive microbubbles comprising an inert gas therein and having a first shell formed on the outer surface thereof, followed by forming a uniform size distribution of the ultrasound reactive microbubbles through an extruder; and (b) a step of producing liposomes comprising the ultrasound reactive microbubbles distributed in a uniform size and a medicament therein and having a second shell formed on the outer surface thereof, followed by forming a uniform size distribution of the liposomes through an extruder; and a liposome using same.

Method for producing solid dispersion containing hardly soluble polyphenol

Provided is a method of producing a solid dispersion that can improve solubility of a hardly soluble polyphenol in water. Specifically, provided is a method of producing a solid dispersion containing an amorphous hardly soluble polyphenol, the method including the steps of: mixing (A) a hardly soluble polyphenol, (B) at least one selected from the group consisting of a plant-derived polysaccharide, a seaweed-derived polysaccharide, and a microorganism-derived polysaccharide, a plant-derived polypeptide, and a microorganism-derived polypeptide, and (C) at least one selected from the group consisting of a monosaccharide and a disaccharide, followed by melting of the mixture by heating; and solidifying the molten product by cooling.

Process for producing a nano resveratrol microemulsion system
10882012 · 2021-01-05 · ·

The present invention relates to a process of producing a nano resveratrol microemulsion system includes: (i) preparing a dispersal phase by dissolving resveratrol in an ethanol solvent; (ii) preparing a carrier by heating a liquid PEG (polyethylene glycol) accounted from 40 to 60% by mass of the mixture of PEG and water to a temperature ranging from 60 to 80 C., then adding zeolite catalyst (0.1-0.4% by mass of mixture of PEG and water), stirring evenly; (iii) adding the carrier to the dispersal phase (in a ratio by mass of 40:60), continuing heating the said dispersal phase to 100 C., stirring at a speed of 400 to 800 rpm; (iv) elmusifying as follows: when the temperature arrives at 100 C., adding Tween to the mixture of the carrier and dispersal phase in step (iii) in a ratio by mass of 40:60, continuing to stir at a speed of 500 to 700 rpm, at a temperature of 100 C. to 130 C. perform emulsification at speed of 2500 to 3500 rpm, combining stirring at a speed of 400 and 600 rpm, in vacuum, the reaction temperature is maintained at 150 C. for 3 to 5 hours, the reation is quenched, the temperature is decreased slowly until it is in the range of 40 to 60 C.; (v) filtrating the product by injecting through nanofilter system before filling-packaging.

Method for producing dispersions of a defined particle size
10835877 · 2020-11-17 · ·

A method for producing dispersions with a defined particle size includes following steps: A) Preparation of a mixed dispersion in a predispersion process, B) introduction of the mixed dispersion into at least one continuously operating separating device, C) separation of the mixed dispersion in the separating device into coarse particles of a coarse-part dispersion and into fine particles of a fine-part dispersion, D) discharging the fine particle dispersion from the separating device into at least one storage tank, E) discharging the coarse particle dispersion from the separating device into at least one disperser, F) grinding the coarse particles of the coarse particle dispersion in the disperser into a dispersed particle mixture and returning the dispersed particle mixture to the mixing tank in the predispersion process, and G) mixing the dispersed particle mixture returned to the predispersion process with the mixing dispersion produced in the predispersion process in the mixing tank.

PROCESS FOR PRODUCTION OF NANO-MICROEMULSION SYSTEM OF PLANT OIL TRIGLYCERIDES
20200346174 · 2020-11-05 ·

The application refers to process for production of a nano-microemulsion system of plant oil triglycerides, including: (i) preparing a dispersed phase plant oil triglyceride; (ii) preparing a carrier made from a mixture of propylene glycol monocaprylate and lecithin by a weight ratio of 5-6:1-1.5; (iii) adding the carrier to the dispersed phase by a weight ratio of 3-4:1-1.5, wherein the dispersed phase temperature is maintained between 60-100 C. while stirring under vacuum, followed by introduction of the whole mixture through the high-pressure microjet homogenizer; (iv) adding Tween 80 and Tween 60 to the solution mixture obtained in step (iii) by a weight ratio of 3-4:1-1.5:1-1.5, wherein the temperature of the dispersed phase is continuously maintained between 60-100 C. while stirring under vacuum; and (v) forming a nano-microemulsion system of plant oil triglycerides by cooling the mixture, followed by homogenization of the mixture by ultrasonication to achieve a droplet size of less than 100 nm, quality control of the resultant product by dissolution thereof in water and measurement of the transparency, in which if the required transparency is not met, continue to heat and measure the transparency until the required transparency is met, then stop the reaction, and emulsification of the mixture to obtain a nano-microemulsion system of plant oil triglycerides.

HIGH-EFFICIENCY AIRLIFT PUMP

This document describes a gas streaming device for use between an injection port and a mixing chamber within an airlift pump, and an airlift pump with the gas streaming device. The gas streaming device includes a planar plate with multiple holes extending therethrough, where the holes are dimensioned to direct the gas into multiple micro-streams for streaming air from the injection port into the mixing chamber. An airlift pump in combination with such a gas streaming device is useful for removing anomalously high concentrations of dissolved gas in a liquid. The increased efficiency for this invention may also enable this type of pump to be economic in other applications where it is desirable to lift a liquid or induce flow.

Method for preparing microcapsules by double emulsion
10807060 · 2020-10-20 · ·

A method for preparing solid microcapsules, comprising the steps of adding under agitation a composition C1 comprising at least one active material to a cross-linkable liquid composition C2, the active material is not an additive to be used in the lubricant, fuel or bitumen industries, drilling sludges or muds, or oil exploration/production, compositions C1 and C2 being immiscible with each other. A first emulsion is obtained comprising droplets of composition C1 dispersed in composition C2, adding under agitation the first emulsion to a liquid composition C3, composition C3 and composition C2 being immiscible with each other, to obtain a second emulsion comprising droplets dispersed in composition C3. Loading the second emulsion in a mixer which applies a homogeneous controlled shear rate to said second emulsion, said shear rate being from 1 000 s-1 to 100 000 s-1, to obtain a third emulsion comprising droplets dispersed in composition C3, and cross-linking the droplets so that solid microcapsules dispersed in composition C3 are obtained.