The present invention relates to a hygienization generator system and method for producing customized disinfection solutions by combining aqueous ozone and alkaline water. The system includes an aqueous ozone generator with an ion exchange material and electrolysis unit, an alkaline water generator capable of producing water with adjustable pH levels, and a mixer to form a homogeneous solution. A control system dynamically adjusts ozone concentration and pH levels based on user inputs or preconfigured settings, with real-time feedback provided by integrated sensors. The system features a user interface for parameter selection, remote monitoring capabilities, and optional microfoaming technology to enhance solution efficacy. Applications include surface sanitization, produce washing, dental water line disinfection, and biofilm removal in industrial piping. The portable configuration supports on-site use with modular dispensing options. This invention overcomes prior shortcomings, offering precise, eco-friendly, and versatile disinfection solutions.

The disclosure is directed at methods for reducing the bioburden of both particles comprising an active pharmaceutical ingredient (API) and the equipment used to process such particles.

Disclosed are methods and compounds useful for forming coatings applied to porous and non-porous surfaces to make the surface antimicrobial and to protect against contaminants. The coatings are formed from phenolic compounds present in a solvent either alone or in combination with other compounds, such as metallic salts.