An improved dressing is presented which enables quicker wound closure and a lower anesthesia requirement, comprised of an improved prior-art skin-substitute. The improvements consist of variations in the thickness of the woven portion of the dressing, to increase wound adherence.

The present disclosure relates to homogeneous or heterogeneous polymer foam structures having a graphic printed thereon. As discussed herein, foam structures, such as for example High Internal Phase Emulsion (HIPE) foam structures may include a first surface and a second surface opposite the first surface, and one or more graphics may be printed directly on the first and/or second surfaces of the foam. The graphic may comprise ink positioned on the first and/or second surface, wherein the ink may penetrate into the foam structure below the surface on which the ink is applied. As such, the ink may reside on the foam structure and/or within the foam structure at various depths below the first and/or second surface.

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phyto-pharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment.

An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (T.sub.g) of the SMP foam to below 25° C. Other embodiments are described herein.

Bacteria-responsive core-shell nanofibers and a process for the preparation thereof are described. The nanofibers release of an antibacterial agent in response to the presence of bacteria. The core of the nanofiber comprises a biocompatible polymer together with an antibacterial agent such as a quaternary ammonium compound, for example benzyl dimethyl tetradecyl ammonium chloride (BTAC). Surrounding the core is shell comprised of a bacterially degradable polymer, which is susceptible to break-down by bacterial enzymes such as lipase, or to acidic pH conditions. The shell may comprise, for example, polycaprolactone (PCL) and poly(ethylene succinate) (PES). The nanofibers may be incorporated into wound dressings.

A therapeutic cushioning boot includes a foot portion configured to receive a foot of a user, and a leg portion configured to receive a leg of the user. The leg portion includes at least a first support chamber and a second support chamber. A first fiberfill material is provided in the first support chamber at a first concentration, and a second fiberfill material provided in the second support chamber at a second concentration that is less than the first concentration.

The present invention relates to a compression bandage for treating wounds comprised of a linear elastic compression wrap and a sterilized polymer foam layer containing a plurality of antimicrobial dyes with at least one dye being gram positive and at least one other dye being gram negative and a biofilm reduction agent and wherein said foam is secured to said linear elastic compression wrap.

A wound care device that can be effectively attached to a wide range of wound locations without the use of any adhesives, can apply controlled, consistent pressure to the wound, and can be configured to allow the clinician to see relevant areas of the patient's body is disclosed. The wound care device includes a contact pad connected with a securing strap. The securing strap includes an inelastic strap segment and an elastic strap segment. The elastic strap segment is coupled with an attachment segment, which attaches to the inelastic strap segment and cooperates with the elastic strap segment to compress the contact pad to the wound.

The present invention relates to a wound healing PVA sponge dressing using negative capillary pressure of the dressing material together with auxiliary negative pressure for wound treatment. The PVA sponge dressing is pretreated with gram positive and gram negative biocidal 5 dyes for insertion into or over a wound. A negative pressure pump is mounted to the PVA sponge dressing to produce additional capillary pressure for withdrawing fluid or water vapor from the sponge dressing and a cover is mounted over the sponge material and negative pressure pump forming a unitary sealed package for placement over a wound.

A haemostatic composition comprising a non-acidic meshed network of fibrous material, wherein the network comprises fibres with a mean diameter (Dso) no greater than 1 μm, an aspect ratio (mean fibre length/mean fibre diameter) of at least 100, and wherein said meshed network has a specific surface area of at least 1O m.sup.2/g, and a gel point no greater than 3 g/L.