Chronic wounds are medical care concern and severe clinical challenge worldwide. A nanofiber based new wound dressing scaffold and a method of developing thereof for treating diabetic wounds is described here. More specifically, the present invention relates to the preparation of biocompatible Polyacrylonitrile (PAN) nanofiber scaffold comprising of Quercetin, Zinc oxide and polyacrylonitrile by electrospinning. The nanofibers formed has the average diameter of approximately 160 nm and show excellent antibacterial and wound healing potentials.

An open-cavity, reduced-pressure treatment device and system for treating a cavity in a patient's body, such as an abdominal cavity, is presented. In one instance, an open-cavity, reduced-pressure treatment device includes a plurality of encapsulated leg members, each having an interior portion with a leg manifold member and formed with fenestrations operable to allow fluid flow into the interior portion, and a central connection member fluidly coupled to the plurality of encapsulated leg members. The central connection member has a connection manifold member. The open-cavity, reduced-pressure treatment devices, systems, and methods allow for, among other things, removal of fluids.

Provided herein are methods for making foam materials and foam material products having a polyurethane foam matrix defining a plurality of pores, a hydrophilic agent retained within at least a portion of the pores for improving an absorption of the foam material, a salt retained within at least a portion of the pores in an amount sufficient to render the foam material isotonic, a surfactant retained within at least a portion of the pores in an amount sufficient to be released upon contact with a moist surface. Also provided herein are methods for making a multilayer foam by casting a second foam layer on a first foam layer substrate and compressing the second foam layer before the second layer is fully cured to form an interface layer in situ.

Dressings, systems and methods of treating a tissue site are described. A method of manufacturing the dressing can include providing a dressing material. The dressing material can have a surface configured to contact the tissue site. The dressing material can also have a plurality of pores. The method can further include applying a compressive force to the dressing material at an angle to the surface, the compressive force causing permanent deformation of the plurality of pores. Causing permanent deformation of the plurality of pores can comprise forming a plurality of compressed pores. Forming a plurality of compressed pores can include compressing the plurality of pores from a generally circular shape to a generally ovular shape.

A correction protection tool for an ingrown toenail includes an armor stocking having a first armor stocking end and a second armor stocking end. The first armor stocking end has a first armor stocking end opening to receive a toe. The second armor stocking end has a second armor stocking end opening to expose a toenail of the toe. An armor cone has a first armor cone end and a second armor cone end. The first armor cone end has a first armor cone end opening to receive the armor stocking. The second armor cone end surrounds the second armor stocking end to protect the toenail.

Provided herein are methods for making foam materials and foam material products having a polyurethane foam matrix defining a plurality of pores, a hydrophilic agent retained within at least a portion of the pores for improving an absorption of the foam material, a salt retained within at least a portion of the pores in an amount sufficient to render the foam material isotonic, a surfactant retained within at least a portion of the pores in an amount sufficient to be released upon contact with a moist surface. Also provided herein are methods for making a multilayer foam by casting a second foam layer on a first foam layer substrate and compressing the second foam layer before the second layer is fully cured to form an interface layer in situ.

The present invention relates to an adherent interface dressing intended for application directly to a wound. Said adherent interface dressing includes a non-adherent cohesive gel formed from a hydrophobic elastomeric matrix consisting of a styrene-(ethylene/butylene)-styrene or styrene-(ethylene/propylene)-styrene triblock elastomer optionally associated with a styrene-(ethylene/butylene) or styrene-(ethylene/propylene) diblock copolymer; said elastomer plasticized by means of a mineral oil, and containing dispersed therein a small quantity of hydrophilic particles of a hydrocolloid; and a flexible open-mesh fabric, said fabric including threads coated with the non-adherent cohesive gel such as to leave the meshes substantially unsealed, The fabric is a heat-set knit with weft yarns, said yarns being continuous multifilament yarns with non-elastic filaments, whereof the extensibility in the transverse direction measured in accordance with standard EN 13726-4 is between 0.01 and 0.5 N/cm.

A method of manufacturing a reduced-pressure abdominal treatment system for treating an open abdominal cavity is provided. In some embodiments, the reduced-pressure abdominal treatment system has an open-cavity treatment device for providing reduced-pressure treatment to an abdominal cavity; a deep-tissue closure device for applying a closing force on a deep-tissue wound; and a surface-wound closure subsystem for providing a closing force on a surface wound. The method of manufacturing may also include providing a reduced-pressure supply subsystem. A method of treatment using a reduced-pressure abdominal treatment system is also disclosed.