A drug dosage form is provided in the form of a solid tablet which is greater than 50% by weight the local anesthetic agent. The local anesthetic agent may be selected from the group consisting of an aminoamide, an aminoester, and a combination thereof. The drug tablet may be in the form of a mini-tablet which is greater than 70 wt % drug, with the balance being excipient. For example, the anesethetic agent may include lidocaine, in a salt or base form, combined with binder and lubricant excipients. Implantable drug delivery devices including the tablets are also provided, e.g., one or more of the drug tablets may be contained in a biocompatible housing. The drug tablets may be substantially cylindrical with flat end faces, and the device may have from 10 to 100 drug tablets aligned in the housing with the flat end faces of adjacent tablets abutting one another.

Systems and methods for measuring tobacco for packaging in pouches are disclosed. A system includes a hopper structured and arranged to hold a granular material in a hopper cavity. The system also includes a measuring system including a measuring cavity and a tube that is slidable in the hopper cavity between a first position unaligned with the measuring cavity and a second position over and aligned with the measuring cavity. The measuring system is configured to continuously communicate a vacuum to the measuring cavity. The measuring system is configured to move a portion of the granular material from the hopper cavity to the measuring cavity when the tube is in the first position. The measuring system is configured to move the portion of the granular material from the measuring cavity to a pouch making machine using pressurized gas that overcomes the vacuum when the tube is in the second position.

Systems and methods for measuring tobacco for packaging in pouches are disclosed. A system includes a hopper structured and arranged to hold a granular material in a hopper cavity. The system also includes a measuring system including a measuring cavity and a tube that is slidable in the hopper cavity between a first position unaligned with the measuring cavity and a second position over and aligned with the measuring cavity. The measuring system is configured to continuously communicate a vacuum to the measuring cavity. The measuring system is configured to move a portion of the granular material from the hopper cavity to the measuring cavity when the tube is in the first position. The measuring system is configured to move the portion of the granular material from the measuring cavity to a pouch making machine using pressurized gas that overcomes the vacuum when the tube is in the second position.

The present invention relates to a loading device for loading particulate material, comprising a body with a first opening and a second opening, wherein a gasket is arranged at the first opening. The present invention also relates to a mixing device with a loading device according to the invention and a method of loading particulate material using the loading device according to the invention.

The present invention relates to a loading device for loading particulate material, comprising a body with a first opening and a second opening, wherein a gasket is arranged at the first opening. The present invention also relates to a mixing device with a loading device according to the invention and a method of loading particulate material using the loading device according to the invention.

A container includes a multilayered composite film combination forming a bag defining a product fill opening. The multilayered composite film combination includes first and second polymer film inner and outer layers each having vacuum holding properties, and a third polymer film disposed between the first and second polymer films. The third polymer film has oxygen barrier properties. Product is packed into the container by coupling a fill spout of the container with a fill tube of a product filling apparatus, and oxygen is drawn from an inner cavity of the container. Fluidized product entrained in nitrogen and/or carbon dioxide gas is flowed through the fill spout of the container, and nitrogen is added into the inner cavity through the fill spout of the container. The fill spout of the container is sealed while a negative pressure is drawn within the inner cavity thereby immobilizing the product within the container.

A drug dosage form is provided in the form of a solid tablet which is greater than 50% by weight the local anesthetic agent. The local anesthetic agent may be selected from the group consisting of an aminoamide, an aminoester, and a combination thereof. The drug tablet may be in the form of a mini-tablet which is greater than 70 wt % drug, with the balance being excipient. For example, the anesthetic agent may include lidocaine, in a salt or base form, combined with binder and lubricant excipients. Implantable drug delivery devices including the tablets are also provided, e.g., one or more of the drug tablets may be contained in a biocompatible housing. The drug tablets may be substantially cylindrical with flat end faces, and the device may have from 10 to 100 drug tablets aligned in the housing with the flat end faces of adjacent tablets abutting one another.

A drug dosage form is provided in the form of a solid tablet which is greater than 50% by weight the local anesthetic agent. The local anesthetic agent may be selected from the group consisting of an aminoamide, an aminoester, and a combination thereof. The drug tablet may be in the form of a mini-tablet which is greater than 70 wt % drug, with the balance being excipient. For example, the anesthetic agent may include lidocaine, in a salt or base form, combined with binder and lubricant excipients. Implantable drug delivery devices including the tablets are also provided, e.g., one or more of the drug tablets may be contained in a biocompatible housing. The drug tablets may be substantially cylindrical with flat end faces, and the device may have from 10 to 100 drug tablets aligned in the housing with the flat end faces of adjacent tablets abutting one another.

The present disclosure relates to a filling machine and a method for filling of filling medium, in particular for the production of sausages with a hopper for accommodating filling medium, a conveyer for supplying the filling medium and a filling element, in particular a filling tube, as well as a device for measuring the filling level in the hopper. The device for measuring the filling level comprises a radar sensor.

The present disclosure relates to a filling machine and a method for filling of filling medium, in particular for the production of sausages with a hopper for accommodating filling medium, a conveyer for supplying the filling medium and a filling element, in particular a filling tube, as well as a device for measuring the filling level in the hopper. The device for measuring the filling level comprises a radar sensor.