Methods and systems of applying physical stimuli to tissue are disclosed. The methods can include reducing or suppressing pancreatitis in a subject by administering a low magnitude, high frequency mechanical signal on a period basis and for a time sufficient to reduce or suppress pancreatitis. The methods can include enhancing healing of damaged tissue in a subject by administering to the subject a low magnitude, high frequency mechanical signal on a periodic basis and for a time sufficient to treat the damaged tissue. The systems can include a device for generating a low magnitude, high frequency physical signal and a platform for applying the low magnitude, high frequency physical signal to the subject for a predetermined time.

In various embodiments, non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries are provided. In some embodiments the methods involve administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces locomotor activity.

The present invention relates to a rehabilitation system for rehabilitating a person with a neurological condition, such as a spinal cord injury (SCI). The system includes exercise equipment for enabling the person to exercise. One or more sensors are provided for sensing information from the person during exercise. The system also includes a model of the exercising person configured to receive the sensed information from the sensors and generate electrical stimulation for the person. Advantageously, the personalized computer model may be used to generate suitable electrical stimulation for the person, and avoid excessive stresses on the person which can lead to the fracturing of bones.

In various embodiments, non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries are provided. In some embodiments the methods involve administering transcutaneous electrical spinal cord stimulation (ISCS) to the mammal at a frequency and intensity that induces locomotor activity.

Apparatus (30) for detecting motion of a device (1) for electrical stimulation of a subject is described. The apparatus (30) comprises a motion detector (2) to detect the motion of the device (1) and generate a motion output signal in response to the detected motion. The motion output signal is indicative of the amount of detected motion. A processor (21) is coupled to the motion detector (20). The processor (21) receives (72) the motion output signal from the motion detector (20) and generates a first processor output signal in response to the received motion output signal. An output device (14, 26) is coupled to the processor (21). The output device (14, 26) receives the first processor output signal from the processor (21) and generates a first output signal in response to the received first processor output signal. The processor (21) generates the first processor output signal if either: (i) the received motion output signal is greater than a threshold; or (ii) the received motion output signal is less than a threshold.

A device for bilateral rehabilitation of a user's limbs, includes a main body connected to a base, a first motor and a second motor supported by the main body, a first and second rotary interfaces supported by the main body rotatably operable about first and second rotation axes by the motors. Grip accessories have a grip portion and a coupling portion couplable to the first and second rotary interfaces. An electronic control device is configured to control rotary movements and torques applied to the first and second rotary interfaces depending on angular positions or torques detected by a position or torque detector. The main body is connected to the base by an adjustable and lockable joint allowing adjustment and locking of the position of the main body with respect to the base in at least three different body positions with different orientations of the first and second rotation axes.

Methods and systems to reduce symptoms of cerebral palsy in children are disclosed herein. In one embodiment, a method for alleviating spasticity of a lower extremity caused by a brain injury includes attaching at least one electrode on a surface of patient's skin, proximate to patient's spinal cord. The method also includes subjecting the patient to a regimen of training that improves walking of the patient; applying a series of pulses to the at least one electrode while the patient is in training; and in response to applying the series of pulses to the at least one electrode, inducing stimulation in the spinal cord that alleviates spasticity of the lower extremity.

Provided is a method for treating musculoskeletal atrophy in patients suffering from a neurological or neuromuscular disease or disorder by combining testosterone replacement therapy with neuromuscular electrical stimulation of multiple muscle groups and, optionally, physical activity.

In various embodiments, non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries are provided. In some embodiments the methods involve administering transcutaneous electrical spinal cord stimulation (ISCS) to the mammal at a frequency and intensity that induces locomotor activity.

An exercise and stimulation device may include an exercise apparatus including a resistive member resisting a motion of a part of a user's body; and a stimulation device removably engaging both the resistive member and the part of the user's body for providing at least two different stimulations to the user's body, where the at least two different stimulations are different than one another.