The invention relates to a system (10) for transporting loose sterile closure elements (12) from the surroundings (14) of an isolator (16) into an interior (18) of the isolator, comprising a container (24) for storing a stock quantity of closure elements in the surroundings of the isolator, an isolator opening (20) and a collecting device (56) for collecting the closure elements and for providing the closure elements in the interior of the isolator, with a metering device (46) for controlling a target quantity of closure elements to be transported from the container through the isolator opening and into the collecting device.

Provided is a capsule filling apparatus including: a conveyance body 10 configured to convey a capsule body 30; and a filling unit 20 configured to fill a filling material in the capsule body 30 conveyed to a filling position P, in which the filling unit 20 includes a hopper 21, a holding chamber 22c, an auger 23, and a paddle 24, the auger 23 is rotationally driven around a first rotation shaft 23a extending in a vertical direction in a hopper 21, the paddle 24 is rotationally driven around a second rotation shaft such that a push-in blade 24b slides along an upper surface 11 of the conveyance body 10 in the holding chamber 22c, and the first rotation shaft 23a and the second rotation shaft are arranged such that axes of the first rotation axis and the second rotation axis coincide with each other.

Provided is a capsule filling apparatus including: a conveyance body 10 configured to convey a capsule body 30; and a filling unit 20 configured to fill a filling material in the capsule body 30 conveyed to a filling position P, in which the filling unit 20 includes a hopper 21, a holding chamber 22c, an auger 23, and a paddle 24, the auger 23 is rotationally driven around a first rotation shaft 23a extending in a vertical direction in a hopper 21, the paddle 24 is rotationally driven around a second rotation shaft such that a push-in blade 24b slides along an upper surface 11 of the conveyance body 10 in the holding chamber 22c, and the first rotation shaft 23a and the second rotation shaft are arranged such that axes of the first rotation axis and the second rotation axis coincide with each other.

Systems and methods for manufacturing and inserting a predetermined number of material-filled pouches into containers are disclosed. A system includes a pouch providing system comprising a plurality of lanes, wherein each one of the plurality of lanes includes a pouch making machine and a hold-back structure. The system also includes a conveyor system structured and arranged to move a plurality of containers into alignment with the plurality of lanes. The system further includes a controller structured and arranged to control the hold-back structure in each one of the plurality of lanes such that the pre-determined pouches are inserted into the plurality of containers when the plurality of containers are aligned with the plurality of lanes.