A system of managing the sterilisation of empty flexible pouches (1) provides applying sacrificial closures (200) to the empty pouches, loading the empty provisional closed pouches to be sterilised on a transport device (300) for the collective transportation, performing the sterilisation of the transport device (300) carrying the empty provisional closed pouches, and finally separating, in a sterile chamber, the sacrificial closures (200) from the pouches, filling and applying a tamper-proof cap (100).

An apparatus for removing excess of a sterilization agent from a web of carton-based packaging material is presented. The web comprises a number of consecutively arranged sections arranged to be formed into packages, wherein each section of the web comprises an opening device attached thereto, wherein at least a subset of the sections comprises a positioning element. The apparatus comprises a positioning element reader arranged to determine a position of the positioning element comprised in or on the web, a control unit configured to estimate a position of the opening device based on the position of the positioning element, and an air pulse device arranged to provide an air pulse, wherein the control unit is further configured to adjust the air pulse device based on the position of the opening device, and the air pulse is provided onto an opening device area of the web such that sterilization agent is removed from the opening device.

Provided are a method and an apparatus for sterilizing a sleeve that can shorten a sterilization process for a paper container sleeve and ensure a sterilization effect. In a method for sterilizing a sleeve in an aseptic filling system that molds the sleeve into a paper container having a bottomed tubular shape by closing surfaces of an open end part of the sleeve and performs sterilization, filling and sealing of the paper container, the sleeve being a tubular body having walls formed by laminating at least paper, in a state where the sleeve stands in a columnar shape, heated air containing a sterilizer is blasted to an inner surface of the sleeve that is to form a bottom part of the paper container to perform sterilization of the inner surface of the bottom part and heating for the closing at the same time.

A disposable isolator including a bottom, a flexible peripheral wall defining a clean and sterile inner volume, a first pair of joining parts forming a first tight junction at the bottom, this first pair including an inner part placed inside the inner volume and suitable for positioning containers, and an outer part placed outside the inner volume and suitable for cooperating by shape matching with a positioning cavity provided on a support table, and a second pair of joining parts forming a second tight junction at the peripheral wall and including an outer part suitable for being connected to a robot, and an inner part suitable for being connected to a manipulating tool, the first and second pairs being designed so that the robot applies the manipulating tool on the containers positioned on the support table.

Methods of manufacturing shelf stable pods containing food or drink to be rapidly cooled, include inserting a mixing paddle into an aluminum can through an open end of a body of the can and sterilizing the can and mixing paddle at temperatures below a stress relief temperature of the can in a first aseptic chamber. The method also includes filling the can with a sterilized food or drink in the aseptic chamber, sealing a sterilized base of the can to the open end of the body of the can with a food-safe adhesive to create a hermetic seal, removing the can from the first aseptic chamber while maintaining the hermetic seal outside the first aseptic chamber, and mechanically seaming the base to the can.

Methods for providing a plurality of convenience kits for sterilizing and delivering a quantity of medicine into the safety of a sterile chamber inside closed system (which can be disposed in a potentially contaminating field environment) are disclosed for container filling applications including Avastin. fortified antibiotic eye drops, mitomycin and hazardous drugs, in general. The containers can include medical syringes, eye drop bottles, vials and product quality assurance containers. A syringe needle cap effective in containment of fluids dispensed from a syringe while being primed is also disclosed.

A sterilization unit for sterilizing a product can include a body having an internal volume for receiving the product to be sterilized, and comprising at least one opening through which product can be introduced and/or withdrawn from the internal volume; a gas inlet in fluid communication with the internal volume for introducing one or more of an inert gas and a sterilizing gas into the internal volume during sterilization; a screen disposed in the gas inlet through which the one or more of the inert gas and the sterilizing gas must pass before entering into the internal volume; and a pressure release valve. The body can be capable of being pressurized to a pressure of 10 atm or more.

A container lid is provided herein having structurally reinforcing ribs therein. The ribs increase the strength of the lid across a central region thereof. Specifically, the lid can have an outer perimeter and the ribs can be spaced inwardly from the outer perimeter. The inwardly spaced ribs can provide a distinct look for consumer differentiation. Additionally, the ribs can be arcuate so that they generally follow a curvature of the outer perimeter of the lid. As such, a label region within the lid central region is preserved, while the lid is still strengthened by the ribs.

The present invention aims at sterilizing a film without using liquid hydrogen peroxide. Aseptic filling and packaging apparatus 11 has supplying device 24 for gaseous hydrogen peroxide; sterilization chamber 15 through which film sheet F passes, and to which gaseous hydrogen peroxide is supplied from supplying device 24; ventilation chamber 16 through which film sheet F passes, ventilation chamber 16 being located downstream of sterilization chamber 15; ventilators F1 and F3 that ventilate ventilation chamber 16; and filling and packaging chamber 17 that is located downstream of ventilation chamber 16, wherein filling and packaging chamber 17 has film forming device 17d that forms film sheet F into a plastic film packaging bag in a shape of a bag, and filling device 35 that fills the plastic film packaging bag with a material.

One embodiment of the present invention provides a method for processing plastic containers within an open aseptic converter chamber comprising a sanitized environment, a supply line, a sanitizer device, a perforator device, a sealing device, and a conveyer. During operation, the method includes: providing and filling a container with heated or heatable liquid including water; sealing the container with a seal or cap; cooling the container to create a first headspace pressure; enclosing the container within the chamber; creating an opening in the seal or cap within a sanitized environment of the perforator device; increasing the first headspace pressure to a second headspace pressure by introduction of a sanitized fluid; resealing the container within a sanitized environment of the sealing device; and, transporting or conveying the sealed container away from the chamber.