A packaging apparatus for forming sealed packages filled with a pourable product comprises a delimiting element movably arranged, in use, within a tube and designed to divide the tube in a first space and a second space. The delimiting element is movable along first and second directions opposite one another and substantially parallel to the tube, and between at least a first position and a second position. The delimiting element comprises a main engagement portion configured to abut against a main abutment portion of a gas supply pipe or a filling pipe with the delimiting element being in the first position. The main abutment portion and/or the main engagement portion are designed such that at least one opening and/or at least one channel is present between the main abutment portion and the main engagement portion with the delimiting element being in the first position.

Device for handling a syringe and automated device for preparing intravenous medication comprising said device for handling a syringe The present invention discloses a device for handling a syringe, said syringe comprising a needle covered by a cap, said device comprising a main body which, in turn, comprises: a cap support comprising a housing for the cap of a needle, said housing being configured to hold said cap during removal and/or insertion of the needle from and/or into the cap by means of a linear movement; a device for joint removal of the cap and needle from the syringe by means of a rotation, comprising a slot defining two parallel faces spaced apart from each other and configured to interfere dimensionally with the cap of the syringe; at least one device for closing the syringe by means of a closed system transfer device (CSTD) or a cap, said device comprising a projection for fixing a support for said CSTD or cap, said support being replaceable and comprising a recess having a shape matching that of said projection and a housing of said CSTD or cap. The present invention also discloses a support for a CSTD or a cap, a set comprising said device and at least one support for a CSTD or a cap, a system and a method for handling a syringe and two automated devices for preparing intravenous medication.

The present invention involves both an apparatus and an associated method for confirming the presence or absence of closures in a closure nest inside an aseptic chamber. The apparatus comprises a topographical profiler disposed to monitor the closure nests. Vertical displacements in topographical maps obtained by the profiler are compared with information from a database about the nest and closure combinations. Vertical displacements falling outside predetermined upper and lower bounds are deemed absences of closures. The topographical profiler may be disposed outside the aseptic chamber. The system may be automated via a controller and suitable software. In some embodiments the nests and disposed in the monitored area by robotic articulated arms. In other embodiments the closure nests are moved by vacuum pickup systems. The system and method may also be employed to assess the suitability of a closure nest for closing in an aseptic chamber containers in a container nest.

A containment system for placement in an installation space includes a housing which encloses a process chamber, a dosing station for the aseptic filling of vessels with a liquid, positioned in the process chamber, a transfer port leading into the process chamber, and a functional module which can be moved up to the dosing station, The module includes an element carrier, functional elements installed on the element carrier, and media feed lines connected to the functional elements. The functional module with the element carrier, the functional elements, and the media feed lines is movable from an initial position, through a transfer port leading into the process chamber, to an operating position at the dosing station.

A medical dispensing system with dispensing and pathway components, each of which of a plurality of dispensers and pathways, respectively. The dispensing and pathway components are controlled to minimize contamination between the items being dispensed. Both the dispensing and pathway components have arcs around which the dispensers and pathways are arranged.

Systems and methods permit gloveless filling containers with a product. A filling arm is disposed within the chamber. An optical sensor is configured to locate and target openings of the containers within the chamber. Locations of the openings are used to guide the filling arm to fill the containers with a product.

Method and apparatus are disclosed for capping a plurality of bottles enclosed and sealed in a plastic bag. The method comprises disposing the plurality of bottles in a tray in a predetermined array such that caps, disposed in a plate can be displaced for convenient capping in a single step. Ratchet tools are disclosed for facile threading of caps to bottles.

The system of the invention involves a gloveless aseptic processing system. The automated system is for filling nested pharmaceutical containers with a pharmaceutical fluid substance. A closed sterilizable gloveless isolator chamber is capable of maintaining an aseptic condition, having a sterilization system. The container filling system has a dispensing head for filling the containers, and a container closing system disposed within the gloveless isolator chamber with rams for pushing closures into openings of the nested containers. The container manipulation mechanism is disposed within the gloveless isolator chamber and is capable of positioning the nested pharmaceutical containers within the gloveless isolator chamber including operably disposing the nested pharmaceutical containers with the container filling system and the container closing system. Container tubs sealed by removable covers and contain a container nest bearing a plurality of pre-sterilized pharmaceutical containers.

A sterilizer-filler nozzle assembly for an aseptic packaging machine comprises a form section 40, a product supply duct that has a product outlet portion 4 which lies downstream of a distal end of the form section 40, a sterilization medium supply duct that has a sterilization medium outlet portion 16 which lies between the distal end of the form section 40 and the product outlet portion 4, and an exhaust duct that has an exhaust inlet portion 22 which lies between the distal end of the form section 40 and the product outlet portion 4. A gas supply duct is provided that has a gas outlet portion 10 which lies between the sterilization medium outlet portion 16 and the product outlet portion 4.

The present invention involves both an apparatus and an associated method for confirming the presence or absence of closures in a closure nest inside an aseptic chamber. The apparatus comprises a topographical profiler disposed to monitor the closure nests. Vertical displacements in topographical maps obtained by the profiler are compared with information from a database about the nest and closure combinations. Vertical displacements falling outside predetermined upper and lower bounds are deemed absences of closures. The topographical profiler may be disposed outside the aseptic chamber. The system may be automated via a controller and suitable software. In some embodiments the nests and disposed in the monitored area by robotic articulated arms. In other embodiments the closure nests are moved by vacuum pickup systems. The system and method may also be employed to assess the suitability of a closure nest for closing in an aseptic chamber containers in a container nest.