The disclosed systems and methods relate to improved tamper-proof cases for securely storing and shipping products. In one example, a tamper-proof case comprises a unibody frame constructed from a single piece of material. The unibody frame can comprise six sides and include one or more living hinges that allow the unibody frame to fold into a completed case. Various sides can be configured to receive panels to give the crate additional structure, rigidity, and security. Additionally, the frame can comprise a split-top lid with a self-locking mechanism with a tamper-proof pull tab for opening the lid.