Provided is a plugging-type resin cap which can sufficiently seal a container and in which, upon uncapping of the container, a restraining band loosens after the pressure in the container is released without the application of an excessive force. A plugging-type resin cap (100) includes a restraining band (130), a tab (140), and engagement projections (151). The restraining band (130) has an arcuate restraining portion (131), stoppers (132), and an upwardly projecting portion (133). The stoppers (132) are formed to extend radially outward from the circumferential both ends of the restraining portion (131). The engagement projections (151) are disposed over an outer side surface of a skirt wall (120) in the vicinity of the circumferential both ends of a tab (140). The stoppers (132) and the engagement projections (151) are formed to be fittable with each other.

To provide a plastic cap that can be safely applied to a closed system drug transfer device, prevents the leakage of a drug from a pharmaceutical container, and does not require a plurality of connection adapters when fitting to a medical instrument of the closed system drug transfer device.

There is provided a plastic cap attached to a pharmaceutical container and fitting to a medical instrument used for a closed system drug transfer device, the cap includes a top surface part having a fitting part at the center thereof, a cylindrical skirt part extending downward from an outer periphery of the top surface part and opening at a lower end, and a fitting member fitting inside the skirt part, in which the fitting part includes a lip and an intermediate tube extending downward from the lip, and the skirt part has a lower rubber stopper there inside and the lower rubber stopper has an O-ring shape.

To provide a plastic cap that can be safely applied to a closed system drug transfer device, prevents the leakage of a drug from a pharmaceutical container, and does not require a plurality of connection adapters when fitting to a medical instrument of the closed system drug transfer device.

There is provided a plastic cap attached to a pharmaceutical container and fitting to a medical instrument used for a closed system drug transfer device, the cap includes a top surface part having a fitting part at the center thereof, a cylindrical skirt part extending downward from an outer periphery of the top surface part and opening at a lower end, and a fitting member fitting inside the skirt part, in which the fitting part includes a lip and an intermediate tube extending downward from the lip, and the skirt part has a lower rubber stopper there inside and the lower rubber stopper has an O-ring shape.

The present disclosure belongs to the field of packaging, and provides a rotary sealed packaging container which comprises an outer lid, a hollow inner core and a container body, wherein the inner core is mounted on an opening part of the container body so that the inner core can relatively move in axial direction of the container body and cannot relatively rotate in the circumferential direction, and the outer lid is mounted on the opening part so that the outer lid cannot relatively move in the axial direction and can relatively move in the circumferential direction; the outer lid is internally provided with a hollow thread part, an inner thread is arranged on the inner wall of the thread part, an outer thread is arranged on the outer wall of the inner core, the inner thread of the thread part matches with the outer thread of the inner core.

The present disclosure belongs to the field of packaging, and provides a rotary sealed packaging container which comprises an outer lid, a hollow inner core and a container body, wherein the inner core is mounted on an opening part of the container body so that the inner core can relatively move in axial direction of the container body and cannot relatively rotate in the circumferential direction, and the outer lid is mounted on the opening part so that the outer lid cannot relatively move in the axial direction and can relatively move in the circumferential direction; the outer lid is internally provided with a hollow thread part, an inner thread is arranged on the inner wall of the thread part, an outer thread is arranged on the outer wall of the inner core, the inner thread of the thread part matches with the outer thread of the inner core.

A container having a cylindrical pouring nozzle with an external thread and with a stop; a cap with an internal thread which can be screwed onto the external thread of the pouring nozzle as far as an end position in which the cap bears in the direction of rotation on the stop of the pouring nozzle; and a seal made of a material which is softer than a material of the cap and a material of the pouring nozzle. The seal is fixedly connected to the cap and has a first sealing element which, with the cap screwed on, is arranged in a radial direction between the cap and pouring nozzle and bears on a lateral surface portion of the pouring nozzle.

A container having a cylindrical pouring nozzle with an external thread and with a stop; a cap with an internal thread which can be screwed onto the external thread of the pouring nozzle as far as an end position in which the cap bears in the direction of rotation on the stop of the pouring nozzle; and a seal made of a material which is softer than a material of the cap and a material of the pouring nozzle. The seal is fixedly connected to the cap and has a first sealing element which, with the cap screwed on, is arranged in a radial direction between the cap and pouring nozzle and bears on a lateral surface portion of the pouring nozzle.

The present disclosure belongs to the field of packaging, and provides a rotary sealed packaging container which comprises an outer lid, a hollow inner core and a container body, wherein the inner core is mounted on an opening part of the container body so that the inner core can relatively move in axial direction of the container body and cannot relatively rotate in the circumferential direction, and the outer lid is mounted on the opening part so that the outer lid cannot relatively move in the axial direction and can relatively move in the circumferential direction; the outer lid is internally provided with a hollow thread part, an inner thread is arranged on the inner wall of the thread part, an outer thread is arranged on the outer wall of the inner core, the inner thread of the thread part matches with the outer thread of the inner core.

The present disclosure belongs to the field of packaging, and provides a rotary sealed packaging container which comprises an outer lid, a hollow inner core and a container body, wherein the inner core is mounted on an opening part of the container body so that the inner core can relatively move in axial direction of the container body and cannot relatively rotate in the circumferential direction, and the outer lid is mounted on the opening part so that the outer lid cannot relatively move in the axial direction and can relatively move in the circumferential direction; the outer lid is internally provided with a hollow thread part, an inner thread is arranged on the inner wall of the thread part, an outer thread is arranged on the outer wall of the inner core, the inner thread of the thread part matches with the outer thread of the inner core.

In one general aspect, a method for filling multiple containers with a pharmaceutical product is disclosed, which comprises decontaminating sealed nested materials in a transfer chamber, removing from the sealed nested materials one or both of a container nest holding the multiple containers and a closure nest holding multiple closures, transferring from the transfer chamber to a controlled environment enclosure the removed nest, aseptically filling the containers with the pharmaceutical product, and closing the containers with the multiple closures. The nests are configured to allow multiple closures and containers to be simultaneously aligned concentrically, and closed simultaneously. Spring-loaded retaining structures on the closure nest allow it to releasably retain multiple closures above the corresponding multiple containers. In some embodiments the spring-loaded features are monolithically integrated with the closure nest. The product may be lyophilized in partially sealed containers while the sealing closures are releasably retained by the closure nest.