A method for filling a container (2) with a filling product, comprising the steps of: positioning the container (2) in a filling station (1) so that its mouth (2b) is below the filling valve (9); separating a treatment volume (40) of the neck (2a) comprised between the filling valve (9) and at least one part of the neck (2a) of the container (2) from an external environment (6) containing the body (2d) of the container (2); dispensing plasma into the treatment volume (40) so that it flows over the neck (2a) of the container (2); enabling the filling valve (9) to dispense the filling product into the container (2).

A medical vial filling system is adapted to fill a medical vial with a solution and cap the filled medical vial. A purging system includes a manifold disposed between a filling station and a capping station. The manifold includes a filling inlet port and a plurality of output ports. The output ports are positioned in a space proximate the filling station and in a space over the transport mechanism. A stoppering block includes a capping chamber for receiving a bushing positioned at the capping station. The stoppering block comprises a stoppering inlet port, a first nozzle opening into the capping chamber and a second nozzle extending into the capping chamber and directed into the medical vial when the medical vial is position in the capping station. A supply of non-reactive gas at the filling inlet port directs flow of the non-reactive gas out the manifold outlet ports to evacuate air and substitute the non-reactive gas in the filled medical vial and at the stoppering inlet port directs flow of the non-reactive gas in a flood zone surround a space above the medical vials when the medical vial is positioned in the capping station and in a stream directed into the medical vial when the medical vial is positioned in the capping station.

A method is described for shaping the bottom of hot-filled containers, in which the bottoms of the containers are forced inwardly from a state bulged outwardly, in particular as they cool down. Complex mechanisms for forcing the bottom inwardly are dispensable for the reason that the bottoms are forced inwardly by at least one fluid jet and/or fluid pressure wave. In addition, shaping the bottom can advantageously be carried out in a production region immediately downstream of a closer.

An apparatus for producing plastic containers filled with liquids, wherein the plastic containers are closed with a keg fitting and filled with liquid, includes a connection device for connecting a plastic container with a keg fitting. The connection device is configured to move the plastic container relative to the keg fitting. The apparatus includes at least one cleaning device configured to clean at least an area of the keg fitting during at least one of relative movement of the keg fitting with regard to the plastic container and connection of the keg fitting with the plastic container. The cleaning device is configured to supply a cleaning medium to the keg fitting.

One embodiment of the present invention provides an apparatus for processing sealed plastic containers having a first headspace pressure. The apparatus may include: an open entry port or tunnel for continuously receiving containers; a sanitizer configured to sanitize outside surfaces of the received containers; a perforator configured to perforate or open a cap or seal of the containers within the apparatus; a sealer configured to seal the perforation or opening formed in the cap or seal of the containers; an open exit port of tunnel for continuously exiting the processed containers; and a conveyor system configured to transporting or convey the containers from the open entry port or tunnel, through and within the apparatus, to the open exit port or tunnel and away from the sanitized environment of the apparatus. The apparatus may be further configured to maintain a sanitized environment within the apparatus, perforator, and/or sealer.

The invention relates to a method for aseptic filling of a container with filling product, wherein the container is transported into an area of a sterile space assigned to the container, and then a mouth area of the container is then placed with a cap for filling in a mouth opening of the sterile space. The invention further relates to a sterile filling device for aseptic filling of a container, in particular for carrying out the stated method, with a sterile space which, in the bottom, comprises a mouth opening for a mouth area of a container and, in the lid, comprises a filling valve and a capper, wherein the filling valve or the capper can be brought into alignment with the mouth opening. Moreover, the invention relates to an aseptic machine with a carousel and, arranged on the latter, sterile filling devices which each have a sterile space, wherein an irradiating device is arranged in the periphery of the carousel for the purpose of irradiating at least the sterile filling device with electrons and/or X-rays prior to a filling operation.

This invention relates to a method and to a capping or closing machine for the capping or closing of bottles or similar containers filled with an oxygen-sensitive product.

A device to prevent the drying of nozzles of a machine for the preparation of fluid coloring products having a delivery head includes an anti-drying member and an actuation mechanism to take the anti-drying member from an inactive position distant from the delivery head to an operating position in contact with the delivery head. The actuation mechanism includes an actuation lever oscillating with respect to a fixed support and a group of parallelogram levers commanded by the actuation lever and connected to the anti-drying member so as to keep an upper surface of the anti-drying member constantly parallel to the lower surface of the delivery head during the movement from the inactive position to the operating position.

A plant (1) for filling and closing cans (2) under hygienic conditions which comprises a hygienic compartment (3), a lid applying device (7) and an inlet (30) for a filling material. The lid applying device (7) is arranged in the hygienic compartment (3) and the inlet (30) is formed on the hygienic compartment (3). When used as intended, one or more cans (2) can be assigned to the hygienic compartment (3) and the hygienic compartment (3) can be moved together with the can(s) (2) in the system (1).

The invention relates to a method for estimating a location of an epileptogenic zone of a mammalian brain, a system for performing a method for estimating a location of an epileptogenic zone of a mammalian brain as well as a computer-readable medium including a set of instructions for estimating a location of an epileptogenic zone of a mammalian brain.