A Luer lock includes a tapered female member and a tapered male member defining a passage. A tubing is inserted through the passage. The tubing defines an outer cross-section corresponding to an inner cross-section of the passage. The tapered male member is configured to be inserted into the tapered female member such that the tube is in fluid communication with the tapered female member, and the tubing exerts a compressive force at a mating surface between the tapered male member and the tapered female member to increase friction therebetween and inhibit leakage. The male member may define a side port defined on a side wall thereof. The side port may provide an additional fluid pathway for application of vacuum or pressure through the tapered male member.

An ion exchange resin bag 5 includes a bag body 51 and a reinforcing body 52. The bag body 51 has a bottom surface portion 511 that is provided at an end portion opposite to an end portion where an opening is provided and forms a bottom surface of the bag body, and a side surface portion 512 that is connected to the bottom surface portion 511 and forms a side surface of the bag body 51. The reinforcing body 52 has a first reinforcing portion 521 that is fixed to a boundary portion of the bottom surface portion 511 and the side surface portion 512, and a second reinforcing portion 522 that is connected to the first reinforcing portion 521 and fixed to at least a part of the side surface portion 512 and extends from the first reinforcing portion 521 toward the opening.

An ion exchange resin bag 5 includes a bag body 51 and a reinforcing body 52. The bag body 51 has a bottom surface portion 511 that is provided at an end portion opposite to an end portion where an opening is provided and forms a bottom surface of the bag body, and a side surface portion 512 that is connected to the bottom surface portion 511 and forms a side surface of the bag body 51. The reinforcing body 52 has a first reinforcing portion 521 that is fixed to a boundary portion of the bottom surface portion 511 and the side surface portion 512, and a second reinforcing portion 522 that is connected to the first reinforcing portion 521 and fixed to at least a part of the side surface portion 512 and extends from the first reinforcing portion 521 toward the opening.

A chromatography device (201; 201′) comprising: – at least one chromatography material unit (203), wherein said chromatography material unit comprises a convection-based chromatography material and is of a substantially rectangular shape having a length (L) and a width (W); - at least one fluid distribution system (207) which is configured to distribute fluid into and out from the at least one chromatography material unit (203), wherein said fluid distribution system (207) comprises a distribution device (209a) and a collection device (209b) between which said chromatography material unit (203) is sandwiched, wherein said distribution device (209a) and said collection device (209b) each comprises a number of parallel grooves (255) for distribution and collection respectively of a fluid to be passed through the chromatography material unit (203), wherein said parallel grooves are reaching over substantially the whole length (L) of the chromatography material unit (203) and are distributed over substantially the whole width (W) of the chromatography material unit (203).

A chromatography device (201; 201′) comprising: – at least one chromatography material unit (203), wherein said chromatography material unit comprises a convection-based chromatography material and is of a substantially rectangular shape having a length (L) and a width (W); - at least one fluid distribution system (207) which is configured to distribute fluid into and out from the at least one chromatography material unit (203), wherein said fluid distribution system (207) comprises a distribution device (209a) and a collection device (209b) between which said chromatography material unit (203) is sandwiched, wherein said distribution device (209a) and said collection device (209b) each comprises a number of parallel grooves (255) for distribution and collection respectively of a fluid to be passed through the chromatography material unit (203), wherein said parallel grooves are reaching over substantially the whole length (L) of the chromatography material unit (203) and are distributed over substantially the whole width (W) of the chromatography material unit (203).

A method for producing 225.sup.A including: a method (X) for purifying a .sup.226Ra-containing solution, including an adsorption step of allowing a .sup.226Ra ion to adsorb onto a carrier having a function of selectively adsorbing a divalent cation by bringing a .sup.226Ra-containing solution into contact with the carrier under an alkaline condition, and an elution step of eluting the .sup.226Ra ion from the carrier under an acidic condition; a method for producing a .sup.226Ra target, including an electrodeposition liquid preparation step of preparing an electrodeposition liquid by using a purified .sup.226Ra-containing solution obtained by the method (X), and an electrodeposition step of electrodepositing a .sup.226Ra-containing substance on a substrate by using the electrodeposition liquid; and a step of irradiating a .sup.226Ra target produced by the method for producing a .sup.226Ra target with at least one selected from a charged particle, a photon, and a neutron by using an accelerator.

In some examples, a filter assembly may include a filter including a first gasket having a first channel adjacent to a first side of the filter and a second gasket having a second channel adjacent to a second side of the filter. The first gasket and the second gasket may include a beveled surface adjacent to the filter. The first channel and the second channel may include a diameter of from about 0.01 mm to about 0.5 mm. A finger tightening system may securely hold the filter without any leaks.

A single-use device for separating or purifying a large volume of a mixture of substances including membrane chromatography modules which are fixedly mounted in a predetermined grid and a line system for linking the membrane chromatography modules and for connecting the membrane chromatography modules to each other. A cover or bottom mechanism holding the membrane chromatography modules in position in a predetermined grid may be attached to the upper or lower side of the membrane chromatography modules. At least part of the line system is formed in the cover or the bottom mechanism, with connecting lines between the membrane chromatography modules. In a method of separating or purifying a large volume of a mixture of substances using such a single-use device having a plurality of automated valves and sensors connected to a control unit, the automated valves are controlled based on an evaluation of the parameters measured by the sensors.

There is provided a method of operating a liquid chromatography arrangement, the liquid chromatography arrangement comprising: a solvent pump arranged to flow a liquid solvent over a liquid chromatography column; a restrictor arranged to restrict the liquid solvent from leaving the liquid chromatography column; and a liquid pump arranged to provide liquid flow between the liquid chromatography column and the restrictor, the method comprising: flowing the liquid solvent through the liquid chromatography column using the solvent pump; and controlling a liquid pressure within the liquid chromatography column by providing a liquid flow between the liquid chromatography column and the restrictor using the liquid pump.

There is provided a method of operating a liquid chromatography arrangement, the liquid chromatography arrangement comprising: a solvent pump arranged to flow a liquid solvent over a liquid chromatography column; a restrictor arranged to restrict the liquid solvent from leaving the liquid chromatography column; and a liquid pump arranged to provide liquid flow between the liquid chromatography column and the restrictor, the method comprising: flowing the liquid solvent through the liquid chromatography column using the solvent pump; and controlling a liquid pressure within the liquid chromatography column by providing a liquid flow between the liquid chromatography column and the restrictor using the liquid pump.