Patent classifications
B01D15/265
Chromatography columns and processes
A separation column for expanded bed adsorption comprises a column tube (2), a base (15) carrying an inlet rotor structure (6) for pumping in process liquid, and a top cap (3). The top cap (3) is conical in form, and has a peripheral flange 31 by which it is rigidly fixed to the top edge flange (22) of the column tube (2). The angle of the convergent interior surface (35) of the conical top cap (3) may be between 10 and 25°. A vortex-inhibitor component (8) projects down below the outlet structure (4) at the top of the cap, projecting into the operating space (15) of the column to inhibit rotation of liquid in the column interior. An expanded bed adsorption process is done with upward flow of liquid in the column through a bed of media particles.
Method for protein purification
The present invention provides a method for manufacturing antibodies or a fragment thereof with reduced levels of antibody reduction related impurities.
Method for protein purification
The present invention provides a method for manufacturing antibodies or a fragment thereof with reduced levels of antibody reduction related impurities.
MODULAR FILTRATION SYSTEM AND METHOD
A system for further filtering a liquid extract material after an initial extraction process. In an embodiment, the system includes a semi-rigid filter cup that is substantially cylindrical, the filter cup having a top and a bottom, wherein the top is oriented to receive filter media prior to a filtration process, and material to be filtered during the filtration process. The filter cup includes an integrated deformable flange at the top of the filter cup, an integrated top o-ring that is integrated into the top of the integrated deformable flange and an integrated bottom o-ring that is integrated into the bottom of the integrated deformable flange.
Oleophilic foams for oil spill mitigation
A method of fabricating an oleophilic foam includes providing a foam comprising a base material. The base material is coated with an inorganic material using at least one of an atomic layer deposition (ALD), a molecular layer deposition (MLD) or sequential infiltration synthesis (SIS) process. The SIS process includes at least one cycle of exposing the foam to a first metal precursor for a first predetermined time and a first partial pressure. The first metal precursor infiltrates at least a portion of the base material and binds with the base material. The foam is exposed to a second co-reactant precursor for a second predetermined time and a second partial pressure. The second co-reactant precursor reacts with the first metal precursor, thereby forming the inorganic material on the base material. The inorganic material infiltrating at least the portion of the base material. The inorganic material is functionalized with an oleophilic material.
Removal of metal ions from essential oils
The present invention relates to a method for separating metal ions from a liquid, which method comprises contacting liquid comprising metal ions with non-functionalized cellulose, adsorbing the metal ions to the cellulose, and separating the liquid from the cellulose, wherein the liquid is an essential oil.
METHODS OF QUALITATIVELY AND/OR QUANTITATIVELY ANALYZING PROPERTIES OF ACTIVATABLE ANTIBODIES AND USES THEREOF
The invention provides methods and kits for qualitatively and/or quantitatively analyzing activation and other properties of activatable antibody therapeutic in biological samples, including tissues and/or biofluid samples. The invention also relates to methods of using a capillary-based immunoassay platform to qualitatively and/or quantitatively analyze levels of activation in biological samples, including tissues and/or biofluid samples.
PROCESS FOR REMOVING METHOXYETHANOL FROM A MIXTURE COMPRISING METHOXYETHANOL AND MORPHOLINE
A method for removing methoxyethanol from a mixture comprising methoxyethanol and morpholine makes use of the selective adsorption of methoxyethanol onto a mixed oxide comprising a spinel phase. The mixed oxide comprises 20 to 30% by weight MgO and 80 to 70% by weight Al.sub.2O.sub.3. The spinel phase has the formula MgAl.sub.2O.sub.4. The mixture is a pre-purified reaction output of the reaction of diethylene glycol with ammonia in the presence of an amination catalyst.
PREPARATION OF LITHIUM CARBONATE FROM LITHIUM CHLORIDE CONTAINING BRINES
This invention relates to a method for the preparation of lithium carbonate from lithium chloride containing brines. The method can include a silica removal step, capturing lithium chloride, recovering lithium chloride, supplying lithium chloride to an electrochemical cell and producing lithium hydroxide, contacting the lithium hydroxide with carbon dioxide to produce lithium carbonate.
METHOD FOR SEPARATING EIGHTEEN COMPONENTS IN TRADITIONAL CHINESE MEDICINE COMPOSITION
The disclosure provides a method for separating eighteen components in a traditional Chinese medicine composition, including: (1) preparing the traditional Chinese medicine composition into a total extract of the traditional Chinese medicine composition, separating by resin through sequentially eluting with water, 10% ethanol and 30% ethanol, and collecting the 30% ethanol eluate to obtain a 30% ethanol extract; (2) adding the 30% ethanol extract to a reverse phase silica gel ODS-AQ-HG, and separating in a medium pressure separation column to obtain differently numbered elution dry pastes; (3) dissolving the differently numbered elution dry paste with 30% methanol as a solvent, and passing the solution through a 0.45 m microporous membrane, carrying out a primary separation by high performance liquid chromatography and collecting chromatographic peaks with different retention times, and further purifying by high performance liquid chromatography; finally obtaining the components of eighteen components.