A method for chromatographically separating a first saccharide from a liquid eluent comprising the first saccharide and a second saccharide by passing the liquid eluent through a bed comprising a gel-type strong acid cation exchange resin in calcium form, wherein the resin is provided in bead form and is characterized by comprising at least 20% whole cracked beads.

A method for chromatographically separating a first saccharide from a liquid eluent comprising the first saccharide and a second saccharide by passing the liquid eluent through a bed comprising a gel-type strong acid cation exchange resin in calcium form, wherein precipitated barium sulfate is incorporated within the resin.

Systems and methods for treating produced water and/or flowback water from fracking operations include: an oil water separator; a first filter downstream of the oil water separator; and an electrocoagulation unit downstream of the first filter. Systems and methods can be used for producing a concentrated brine for use in industrial applications and a separate stream of fresh water

The present invention relates to the isolation and purification of sialylated oligosaccharides from an aqueous medium in which they are produced.

The present disclosure relates to a method for preparing L-cysteine crystals, and L-cysteine crystals prepared by the method. Through the method for preparing L-cysteine crystals of the present disclosure, L-cysteine crystals can be obtained from a natural L-cysteine fermentation broth with a high recovery rate and/or purity without a chemical reaction or the use of an artificial synthetic compound.

Combinations of different chromatography modalities with particularly refined conditions significantly reduce acid charge variants in a preparation of monoclonal antibodies. The process for reducing acid charge variants utilizes a combination of anion exchange and hydrophobic interaction chromatography, followed by cation exchange chromatography polishing, whereby the levels of acidic or basic charge species of the monoclonal antibodies may be modulated to a desired level.

Treating a non-wine alcoholic beverage including: exposing the non-wine alcoholic beverage to an ion exchange matrix. The ion exchange matrix includes a mixture of cation exchange media and anion exchange media that includes: (1) cation exchange media that are in hydrogen form, (2) cation exchange media that are in mineral form comprising potassium mineral form, (3) anion exchange media that are in hydroxide form, and (4) anion exchange media that are in chloride mineral form. The exposing results in: binding ions of the mixture to one or more cationic or anionic constituents present in the pretreated beverage, reducing concentrations of the one or more cationic or anionic constituents in the beverage and maintaining a conductivity value of the treated beverage equal to or greater than the pretreated beverage's conductivity value. An apparatus for treating a non-wine alcoholic beverage and a treated non-wine alcoholic beverage prepared by a process are also disclosed.

A process for producing an arginine-rich peptide mixture and the application thereof in cervical cancer therapy is provided. The process includes the following steps: A suspension of walnut meal and egg albumin is pretreated with ultrahigh pressure, and then digested by alkaline proteinase and papain in separated steps with the ultrasonic and microwave-assisted extraction. The peptides of interest are isolated from filtration supernatant obtained after the enzyme digestion by reversed phase high-performance liquid chromatography. By using the peptide mixture as a template, acrylic acid and methyl acrylic acid as functional monomers, triethylene glycol dimethacrylate as cross-linking agent, and isopropylthioxanthone in acetone as a photoinitiator, polymerization is induced by ultraviolet light to form a surface imprinted membrane for isolating and enriching the peptides of interest from the supernatant. The arginine content in the peptide mixture is more than 18%. The arginine-rich peptide mixture is able to strongly suppress the proliferation of human cervical cancer Hela cells. The approach is applicable to reduce the cost of production and speed up the commercialization of large-scale production.

The present invention provides a method of controlling growth of unwanted microorganisms by limiting their access to manganese. More specifically, the present invention provides a method of inhibiting or delaying growth of yeast and mold by reducing the manganese concentration in a product which is preferably a food product. The invention also provides manganese scavengers and uses thereof to inhibit or delay fungal growth.

Method for lowering aldehyde content in a mixture comprising (i) diethylene glycol (DEG) and/or triethylene glycol (TEG) and (ii) aldehyde are disclosed. An ion exchange resin is soaked in monoethylene glycol. The mixture comprising 5 to 200 ppm aldehyde is then flowed to make contact with the soaked ion exchange resin to produce a product comprising DEG and/or TEG and less than 15 ppm aldehyde.