Disclosed is an apparatus and method used to isolate organic acid forms of cannabinoids from a source biomass. This includes the use of a continuous, flow driven, biomass agitation unit, referred to herein as the Continuous Trichome Separator (CTS) Unit. Biomass is fed into the CTS Unit, where trichomes are shaken off of the biomass, and a mixture of trichomes and fluid continue for further processing. The trichomes are melted and then separated using chromatographic separation techniques. Thereafter the organic acids are dehydrated and become isolate compounds.