Provided is a hollow fiber membrane module comprising: a hollow fiber membrane bundle; a housing; a first adhesively-fixed portion and a second adhesively-fixed portion configured to adhesively fix, at both ends of each of the hollow fiber membranes, with a potting material: the hollow fiber membranes to each other, and the hollow fiber membrane bundle to an inner wall of the housing; and a regulating member 40 configured to regulate arrangement of the hollow fiber membranes, wherein: on an end face outer than the housing of at least one of the first adhesively-fixed portion or the second adhesively-fixed portion, when a range of a circle having a center at a center of the end face and a radius equal to ½ of a radius of the end face is defined as a central portion, and a range other than the central portion is defined as a circumferential portion, a ratio of an area ratio of the regulating member 40 and the potting material to an entire area of the central portion to an area ratio of the regulating member 40 and the potting material to an entire area of the circumferential portion is 0.8 or more and 1.2 or less.

A hollow fiber membrane module includes: a tubular case; a hollow fiber membrane bundle; and a pair of sealing and fixing portions, in which an outside-membrane channel that passes by an outer wall of each of the hollow fiber membranes and an inside-membrane channel that passes through the hollow inside of each of the hollow fiber membranes are formed, moist air flows through the outside-membrane channel, and dry air flows through the inside-membrane channel, whereby moisture in the moist air is supplied to the dry air by a membrane separation effect of the hollow fiber membranes, wherein a plurality of spaces are disposed between the case inner wall and the hollow fiber membrane bundle, and a restriction portion that restricts the hollow fiber membrane from entering into the spaces is partially disposed between the hollow fiber membrane bundle and each of the spaces.

The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.

Provided is a membrane distillation module 100 comprising a membrane distillation membrane cartridge 10 and a membrane distillation housing 20, wherein: the membrane cartridge 10 comprises a membrane anchoring part 12 in which porous membranes 11 are anchored by anchoring resin; the housing 20 comprises a housing body 30 and a housing lid 40; the membrane distillation module 100 comprises a support part 60 where the outer surface of the membrane anchoring part 12 is supported by the inner surface of the housing 20 with a seal member 50 interposed therebetween; and a value C in the cross section of the support part 60 is at least 30° C. as represented by the following formula, where d.sub.F is the equivalent circular diameter (mm) of the outer circumference of the membrane anchoring part 12, k.sub.F is the linear expansion coefficient (1/° C.) of the anchoring resin, d.sub.E is the equivalent circular diameter (mm) of the inner circumference of the housing 20; and k.sub.E is the linear expansion coefficient (1/° C.) of a portion where the housing 20 contacts the seal member 50.

Embodiments of the invention pertain to cartridges, systems and methods for performing hemodialysis and related extracorporeal blood treatment modalities and therapies, in which blood flows in the inter fiber space and dialysate flows in the lumens of hollow fibers. Appropriate connectors and fitting orientations may be provided. There may be provided orbital distributors, fanning of fibers, and features to promote uniformity of fiber spacing in the fiber bundle. Orbital distributors may contain contoured surfaces, flow redirectors, non-uniform-conductance flow elements, through-wall distributors, and other features. There may be subdivision of the fiber bundle into two groups of fibers with separate control fluid to each group. Appropriate systems may be provided for various therapies. Flow past the fibers may be parallel, transverse or other configuration. These various features may enable long-term application to all dialysis and ultrafiltration related therapies, and also to other therapies and to applications including implantables, portables and wearables.

A cartridge for non-cryogenically separating a gas into components includes a plurality of hollow polymeric fibers, the fibers being anchored by a pair of tubesheets, each tubesheet being adjacent to a head, the tubesheet and head being joined by a clamshell retainer. The cartridge does not have a core tube. The fibers are enclosed within a sleeve, the sleeve being sufficiently thin so as to be a non-structural element. The cartridge may be inserted within a larger pressure vessel. The cartridge of the present invention can accommodate more fibers than comparable cartridges of the prior art, and therefore has greater throughput.

Disclosed are: a humidifier for a fuel cell, which can reliably prevent gas leaks due to repeated operations and shutdowns of a fuel cell and can be manufactured with relatively low manufacturing costs and high productivity as well; and a method for manufacturing same. A humidifier for a fuel cell of the present invention comprises a humidification module and caps coupled to both ends of the humidification module, respectively. The humidification module comprises: a mid-case having a step on the inner peripheral surface thereof; a plurality of hollow fiber membranes in the mid-case; a fixation layer on which ends of the hollow fiber membranes are potted; a bracket which is supported by the step of the mid-case and is in contact with the fixation layer; and a packing member in contact with the bracket and having a groove into which an end of the mid-case is inserted.

A first adhesion-fixing-portion adhesively fixing hollow fiber membranes together and a hollow fiber membrane bundle and an inner wall of a housing together at an open end of the hollow fiber membranes, and a second adhesion-fixing-portion adhesively fixing the hollow fiber membranes together and the hollow fiber membrane bundle and the inner wall of the housing together at a closed end of the hollow fiber membranes are included. At least one of the second adhesion-fixing-portion and the housing around the second adhesion-fixing-portion has at least one through-hole for introducing liquid fed from the outside of the second adhesion-fixing-portion to a space in the housing. The total area of an opening or openings of at least one through-hole provided outside an outer perimeter of the hollow fiber membrane bundle is 80% or more of the total area of an opening or openings of all of the at least one through-hole.

The present disclosure relates to a process for producing a filtration and/or diffusion device, e.g., a capillary dialyzer or an ultrafilter.

The present invention relates to a hollow-fiber membrane module including: a hollow-fiber membrane bundle including a plurality of hollow-fiber membranes bundled in a potting part; a housing enclosing the hollow-fiber membrane bundle; and a protective member contacting with an outer surface of the potting part and continuously covering the outer surface, in which the protective member has a notched part through which one end of the protective member communicates with another end in a longitudinal direction of the hollow-fiber membrane bundle.