The invention relates to a method for producing a membrane module, comprising a plurality of elongated filter elements disposed in parallel adjacent to one another, each element comprising a longitudinal channel, a housing enclosing the filter elements, and a collector chamber between the housing and the filter elements.

An oxygenator module for gas exchange between blood and a gas in an extracorporeal lung support system, with several layers of semipermeable, gas-perfusable hollow fibers, wherein the hollow fibers of one of the layers are oriented at an angle of rotation about a central longitudinal axis of the oxygenator module with respect to the hollow fibers of another one of the layers, and with a potting which extends along the central longitudinal axis and in which the hollow fibers are fixed, wherein the potting defines a cavity that extends along the central longitudinal axis and in which the hollow fibers are arranged and which is blood-perfusable in the direction of the central longitudinal axis, wherein the potting has an essentially circular inner sheath surface that limits the cavity radially outward; as well as a method for producing the oxygenator module.

Module for gas separation that maintains moisture retention of a gas separation active layer at a uniform level has a composite hollow-fiber membrane configured as the interior of an exterior body and has a porous hollow-fiber support body and a gas separation active layer disposed on the surface of the hollow-fiber support body. The exterior body has a supply port and a discharge port for a first gas passing through the outer side of the composite hollow-fiber membrane, and a supply port and a discharge port for a second gas passing through the inner side of the composite hollow-fiber membrane. The first gas flows through a first space enclosed by the exterior body and the outer side of the composite hollow-fiber membrane and the second gas flows through a second space separated by the composite hollow-fiber membrane and the exterior body. The first space is filled with an absorbing solution.

The invention relates to a method for producing a membrane module, comprising a plurality of elongated filter elements disposed in parallel adjacent to one another, each element comprising a longitudinal channel, a housing enclosing the filter elements, and a collector chamber between the housing and the filter elements.

A method for closing one side of a hollow fiber membrane including a lumen and a wall radially enveloping the lumen, wherein the wall includes an inner textile layer, wherein a portion of a low viscosity resin flows at least partially through a face of the hollow fiber membrane into an end portion of the hollow fiber membrane and closes the end portion with an outer free surface and is being cured by UV light. In order to reduce a propensity for blocking between the end portions of the hollow fiber membranes it is proposed that that the portion is fed in its entirety by positive pressure through the face into the end portion and cured after a time period of 5 seconds at the most, and that the portion is arranged exclusively within the hollow fiber membrane after curing.

The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.

A membrane contactor includes: a cap has an internally beveled surface and a cap port; a cup body has an externally beveled surface in sealing engagement with the internally beveled surface, a side port on a side of the cup body and an end port located on an end of the cup body; and a membrane cartridge is located within the cup body, is sealed to an open end of the cup body, and is in sealed fluid communication with the end port. A method of making a membrane contactor includes the steps of: sealingly mating a perforated center of a membrane contactor with the end port of a cup body; sealingly joining an end of the membrane cartridge adjacent an open end of the cup body; and sealingly joining a beveled surface of the cap to a beveled external surface of the cup body.

A hollow fiber membrane fluid transport device is disclosed wherein the fibers are comprised of Polytetrafluoroethylene (PTFE), and the potting materials are comprised of fluorocopolymer and or fluoroterpolymer based materials. The potting of the device utilizes a compressed chemically resistant fluorocopolymer and or fluoroterpolymer film, allows for ease of manufacture without destruction of the PTFE hollow fibers, with high packing densities, and without the processing complexity of pre-melting, extruding, or chemical crosslinking of any polymeric adhesives. Furthermore, the PTFE hollow fibers can be treated with a fluoropolymeric solvent solution before the chemically resistant film is applied to enhance the adhesion of the PTFE fiber to the film. PTFE hollow fibers, and its respective fluoro-co and terpolymers as potting films impart high packing densities, superb chemical resistance and temperature resistance without membrane contamination, or low fiber pull strength, as is sometimes observed with standard potting materials such as polyurethane and epoxy.

A hollow fiber membrane fluid transport device is disclosed wherein the fibers are comprised of Polytetrafluoroethylene (PTFE), and the potting materials are comprised of fluorocopolymer and or fluoroterpolymer based materials. The potting of the device utilizes a compressed chemically resistant fluorocopolymer and or fluoroterpolymer film, allows for ease of manufacture without destruction of the PTFE hollow fibers, with high packing densities, and without the processing complexity of pre-melting, extruding, or chemical crosslinking of any polymeric adhesives. Furthermore, the PTFE hollow fibers can be treated with a fluoropolymeric solvent solution before the chemically resistant film is applied to enhance the adhesion of the PTFE fiber to the film. PTFE hollow fibers, and its respective fluoro-co and terpolymers as potting films impart high packing densities, superb chemical resistance and temperature resistance without membrane contamination, or low fiber pull strength, as is sometimes observed with standard potting materials such as polyurethane and epoxy.

The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.