Provided is a water collection header (5) for collecting and extracting filtrate from a plurality of membrane modules (4), comprising: a plurality of cylinder portions (6) each including a cylinder body (61) formed in a cylindrical shape in which at least one end portion is opened and formed such that the end portions are sequentially connected to each other in a water-tight state, wherein at least one cylinder portion (6) of the plurality of cylinder portions (6) includes a connection portion (62) connected to the membrane module (4) so that the filtrate flows from the membrane module (4), and wherein at least one cylinder portion (6) of the plurality of cylinder portions (6) includes a water intake portion (63) capable of discharging the filtrate inside the cylinder body (61) to the outside, which is easily assembled.

A dialyzer and a method of manufacture thereof, wherein the dialyzer includes a tubular dialyzer housing in the interior of which a plurality of capillaries each extending in the longitudinal direction of the dialyzer housing and being juxtaposed transversely to the longitudinal direction is arranged, with a filler having a volume-increasing property being arranged between the inner wall of the dialyzer housing and the capillaries.

Disclosed is a header which can prevent a fixing layer for fixing the filtration membrane in the header from being detached from the header and a filtration membrane module comprising the same. A filtration membrane module of the present invention comprises a filtration membrane, a header comprising a case having an opening at an upper part thereof and a partition dividing an inner space of the case into a first space for insertion of the filtration membrane and a second space for fixing the filtration membrane, and a fixing layer. The filtration membrane is potted in the fixing layer which, together with the case, forms a filtrate collecting space in the first space. The partition has a through-hole. The fixing layer exists in at least a portion of the first space, in the second space, and in the through-hole of the partition as well.

The present invention is directed to a method of sealing the free end of a hollow fiber membrane for use in a single header filtration module by dipping the end of the membrane into a low-viscosity light-curable adhesive and curing the adhesive. The invention further encompasses the resulting sealed hollow fiber membrane with a diameter that is only slightly larger than the diameter of the unsealed membrane.

A hollow fiber membrane fluid transport device is disclosed wherein the fibers are comprised of Polytetrafluoroethylene (PTFE), and the potting materials are comprised of fluorocopolymer and or fluoroterpolymer based materials. The potting of the device utilizes a compressed chemically resistant fluorocopolymer and or fluoroterpolymer film, allows for ease of manufacture without destruction of the PTFE hollow fibers, with high packing densities, and without the processing complexity of pre-melting, extruding, or chemical crosslinking of any polymeric adhesives. Furthermore, the PTFE hollow fibers can be treated with a fluoropolymeric solvent solution before the chemically resistant film is applied to enhance the adhesion of the PTFE fiber to the film. PTFE hollow fibers, and its respective fluoro-co and terpolymers as potting films impart high packing densities, superb chemical resistance and temperature resistance without membrane contamination, or low fiber pull strength, as is sometimes observed with standard potting materials such as polyurethane and epoxy.

A hollow fiber membrane fluid transport device is disclosed wherein the fibers are comprised of Polytetrafluoroethylene (PTFE), and the potting materials are comprised of fluorocopolymer and or fluoroterpolymer based materials. The potting of the device utilizes a compressed chemically resistant fluorocopolymer and or fluoroterpolymer film, allows for ease of manufacture without destruction of the PTFE hollow fibers, with high packing densities, and without the processing complexity of pre-melting, extruding, or chemical crosslinking of any polymeric adhesives. Furthermore, the PTFE hollow fibers can be treated with a fluoropolymeric solvent solution before the chemically resistant film is applied to enhance the adhesion of the PTFE fiber to the film. PTFE hollow fibers, and its respective fluoro-co and terpolymers as potting films impart high packing densities, superb chemical resistance and temperature resistance without membrane contamination, or low fiber pull strength, as is sometimes observed with standard potting materials such as polyurethane and epoxy.

A bioreactor has a biofilm that receives a gas through a supporting membrane and another biofilm attached to an inert support. The first biofilm is aerated through the membrane and provides nitrification. The other biofilm has an anoxic or anaerobic zone and provides denitrification. A module useful in the bioreactor has cords potted in at least one potting head. Optionally, some or all of the cords have a gas transfer membrane. The module may provide inert supports, active gas transfer supports or a combination of both types of support. Multiple modules may be assembled together into a cassette, the cassette providing inert supports, active supports or a combination. The module or cassette may have an aerator for mixing or biofilm control.

Disclosed are a bundle of hollow fiber membranes to improve use efficiency of the hollow fiber membranes and a method of manufacturing the same. The bundle of hollow fiber membranes includes a plurality of yarns to form fluid channels and serve as spacers disposed between the hollow fiber membranes to create a bundle. The method includes spinning including supplying a spinning dope to a nozzle and conducting spinning to form a plurality of hollow fiber membranes, coagulating the hollow fiber membranes formed during spinning, and yarn feeding including inserting a plurality of yarns between the hollow fiber membranes to form a bundle. The method is effective in uniformly distributing a fluid through fluid channels formed between the hollow fiber membranes and maximizes usage efficiency of the hollow fiber membranes.

An Oxygenator as a medical instrument includes at least one first hollow fiber membrane layer comprised of a plurality of integrated first hollow fiber membranes, and forms a shape of a cylindrical body as a whole, and at least one second hollow fiber membrane layer disposed at the outer circumferential side of the first hollow fiber membrane layer in a state of being concentric with the first hollow fiber membrane layer, has a plurality of integrated second hollow fiber membranes, and forms a shape of a cylindrical body as a whole. Moreover, each of the first hollow fiber membranes is wound around a central axis, and each of the second hollow fiber membranes is wound around a central axis. The number of times the second hollow fiber membranes are wound is smaller than the number of times the first hollow fiber membranes are wound.

A production method for a medical instrument includes a plurality of integrated hollow fiber membrane producing a base material forming a cylindrically-shaped body. Each of the hollow fiber membranes sequentially passes through a first point, a second point, a third point, a fourth point, and a fifth point that are set on a core member. In an outward path heading toward the third point from the second point, the hollow fiber membrane reaches the third point from the second point at the shortest distance while being wound in the circumferential direction of the core member. Moreover, in a homeward path heading toward the fifth point from the fourth point, the hollow fiber membrane reaches the fifth point from the fourth point at the shortest distance while being wound in the circumferential direction of the core member in the same direction as in the case of the outward path.