A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.

A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.

The invention relates to a device and a method for producing a hollow fibre membrane bundle consisting of hollow fibre membranes, wherein, in the claimed device, a sheaf of hollow fibre membranes is received in a lower semitubular shell and bundled together to form a hollow fibre membrane bundle by a complementary upper semitubular shell.

Provided is a hollow fiber membrane module that exhibits excellent durability even when a chemical such as a radical polymerizable compound is used for a separation or mixing process. Also provided is a method for producing the hollow fiber membrane module in a highly productive manner. More specifically, there is provided a hollow fiber membrane module at least including a tubular body, a cap, a hollow fiber membrane, and an end seal portion, wherein at least a liquid contacting portion of the end seal portion is sealed with a cured product of a curable resin composition including an epoxy resin, and wherein the epoxy resin includes a polyglycidyl ether of a polycondensate of an aromatic compound containing a phenolic hydroxyl group and an aromatic compound containing a formyl group and a phenolic hydroxyl group, and there is provided a method for producing the module.

The hollow fiber membrane module according to the present application is provided with a cylindrical container open at one end and the other end, a bundle of hollow fiber membranes packed in the cylindrical container, potting parts embedding and fixing the bundle of hollow fiber membranes at both ends of the cylindrical container, and headers provided at both ends of the cylindrical container and having nozzles that constitute an inlet and outlet for a fluid. In this hollow fiber membrane module, the headers and the cylindrical container are welded in at least two areas including a primary weld and a secondary weld, and the secondary weld is located in a position where welding is initiated after or simultaneously with the beginning of welding of the primary weld.

The present disclosure relates to processes for the production of capillary dialyzers. The processes involve contact-free thermoforming of bundles of hollow fiber membranes. The present disclosure also relates to an apparatus for contact-free thermoforming of bundles of hollow fiber membranes.

An external-pressure type hollow fiber membrane module in which fouling is not likely to occur in a hollow fiber membrane at the time of filtering operation, and which exhibits excellent washability of the hollow fiber membrane is provided. The first end side and the second end side of a plurality of hollow fiber membrane bundles 60 are fixed with adhesive, together with an inner wall surface of the tubular housing 10 or an inner wall surface of the cap. The adhesive-fixed part of the first end side includes a plurality of raw water introduction holes 65 which are formed therethrough in a thickness direction. An external-pressure type hollow fiber membrane module in which the plurality of raw water introduction holes 65 include first group raw water introduction holes 66 formed at positions including central parts of the plurality of hollow fiber membrane bundles 60, respectively, and second group raw water introduction holes 67 formed between the plurality of hollow fiber membrane bundles 60 and between the plurality of hollow fiber membrane bundles 60 and the inner wall surface of the tubular housing 10.

Hollow fiber cartridges and components and methods of their construction.

A cartridge type hollow fiber membrane module including a housing, a hollow-fiber membrane bundle having a plurality of hollow fiber membranes, a first potting part that bonds the hollow fiber membranes at at least one end of the bundle of the plurality of hollow fiber membranes such that the hollow fiber membranes are open, and a sealing material that fixes the first potting part to the housing liquid-tightly, wherein the first potting part comprises an inner potting part and an outer potting part, wherein the inner potting part and the outer potting part are both formed of a potting material, wherein the sealing material is in contact with the outer potting part, and wherein both the inner potting part and the outer potting part are formed in a sealing direction of the sealing material. The cartridge type hollow fiber membrane module is free of leakage and contamination due to separation of a potting material even when steam sterilization is performed.

Hollow-fibre membrane having at least one first curl in the form of a first wave which is characterized by a first oscillation plane and a first wavelength and at least one second curl in the form of a second wave which is characterized by a second oscillation plane and a second wavelength, characterized in that the first oscillation plane and the second oscillation plane confine an angle with one another which is different from zero.