The present invention provides an intrinsically anti-microbial hollow fiber membrane for filtration of liquids. The membrane comprises a plurality of porous hollow bilayer membrane fibers wherein the liquid enters from outside of the fiber, passing through the porous membrane into the lumen of the fiber and coming out from the hollow ending of the fiber, wherein this configuration provides a liquid outside-in arrangement and retains the filtrate outside. It means that membrane of the invention has built in characteristics to act against microbes in order to provide the use with a safe liquid free from microbes. The outer side or outer wall of the hollow fibers may be configured to become hydrophobic whereas inner side or inner wall of the hollow fiber membrane may be configured to become hydrophilic to enhance the water permeability to a great extent. The hollow fiber membrane may be configured to give it an intrinsic anti-microbial capability. A device containing above said membrane has also been disclosed.

A hollow fiber membrane filtration device includes a hollow fiber membrane module including a vessel having a treated water outlet and a concentrated water outlet; a plurality of hollow fiber membranes each of which separates raw water into permeated water and concentrated water, and is vertically disposed in the vessel; an upper end fixing member that fixes upper end parts of the hollow fiber membranes and is disposed at an upper part in the vessel; a permeated water chamber that is formed on an upper side of the upper end fixing member and communicates with an interior of each of the hollow fiber membranes; and a water conduit through which the raw water is supplied into the vessel. The water conduit vertically extends on a lower side of the upper end fixing member, and a plurality of ejection holes is provided on a side peripheral surface to eject raw water.

A medical product includes a bladder, a filtration device, and a sterile product concentrate. The bladder has a perimeter seal and defining a sterile chamber. The filtration device includes a stem and a filter membrane disposed in line with the stem. The stem extends through the perimeter seal and has an inlet end accessible from outside of the perimeter seal and an outlet end in fluid communication with the sterile chamber. The filter membrane can have a nominal pore size in a range of approximately 0.1 m to approximately 0.5 m, wherein the filter membrane is shaped as a hollow fiber with a wall and pores residing in the wall of the fiber. The sterile product concentrate is disposed in the sterile chamber and adapted to be reconstituted by the introduction of a pharmaceutical fluid into the chamber through the filtration device.

A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.

A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.

The present invention provides an intrinsically anti-microbial hollow fiber membrane for filtration of liquids. The membrane comprises a plurality of porous hollow bilayer membrane fibers wherein the liquid enters from outside of the fiber, passing through the porous membrane into the lumen of the fiber and coming out from the hollow ending of the fiber, wherein this configuration provides a liquid outside-in arrangement and retains the filtrate outside. It means that membrane of the invention has built in characteristics to act against microbes in order to provide the use with a safe liquid free from microbes. The outer side or outer wall of the hollow fibers may be configured to become hydrophobic whereas inner side or inner wall of the hollow fiber membrane may be configured to become hydrophilic to enhance the water permeability to a great extent. The hollow fiber membrane may be configured to give it an intrinsic anti-microbial capability. A device containing above said membrane has also been disclosed.

A membrane assembly includes a tube container having an inlet conduit and a first outlet conduit both oriented in a radial direction, and a second outlet conduit oriented in an axial direction; and a hollow fiber membrane element disposed inside the tube container, the hollow first membrane element comprising a first adapter with an axial permeate fluid passage in a center thereof and an inlet gas passage in a peripheral portion thereof; and a second adapter with an axial permeate fluid passage in a center thereof and a non-permeate fluid passage in a peripheral portion thereof.

The present concentration device includes a membrane module having a first and a second flow paths that are separated by a semipermeable membrane, the module including a U-shaped tube in which the semipermeable membrane is disposed, a first flow-path-inlet and a first flow-path-outlet connection parts, and a second flow-path-inlet and a second flow-path-outlet connection parts, the device including an introducing unit for introducing a subject solution with a predetermined pressure into the first flow path from the first flow-path-inlet connection part, separating the subject solution into a concentrate and a permeate through the semipermeable membrane, passing the permeate through the second flow path, draining the concentrate from the first flow-path-outlet connection part, introducing the subject solution with a pressure lower than the predetermined pressure into the second flow path from the second flow-path-inlet connection part, and draining a diluent diluted with the permeate, from the second flow-path-outlet connection part.

Provided is a filtration device exhibiting a high water treatment capacity and capable of increasing the longevity of a hollow-fiber filter, in a water purification device not requiring a purification material and requiring a high water treatment capacity. The filtration device (3) has: a housing case (15) having a water inlet unit and a water outlet unit arranged on one end side thereof; and a membrane module (17) provided inside this housing case (15). A first flow path (31) for causing raw water that has flowed in from the water inlet unit (21) to flow further to the other end side of the housing case (15) than the membrane module (17), and a second flow path (33) for causing the raw water that has flowed further to the other end side of the housing case (15) along this first flow path (31) to pass through the membrane module (17) and flow to the water outlet unit (23) are provided inside the housing case (15). A spacer (19) is provided on the upstream side of the membrane module (17) in the second flow path (33).

A medical product includes a bladder, a filtration device, and a sterile product concentrate. The bladder has a perimeter seal and defining a sterile chamber. The filtration device includes a stem and a filter membrane disposed in line with the stem. The stem extends through the perimeter seal and has an inlet end accessible from outside of the perimeter seal and an outlet end in fluid communication with the sterile chamber. The filter membrane can have a nominal pore size in a range of approximately 0.1 ?m to approximately 0.5 ?m, wherein the filter membrane is shaped as a hollow fiber with a wall and pores residing in the wall of the fiber. The sterile product concentrate is disposed in the sterile chamber and adapted to be reconstituted by the introduction of a pharmaceutical fluid into the chamber through the filtration device.