Disclosed herein are rolled-membrane microfluidic diffusion devices and corresponding methods of manufacture. Also disclosed herein are three-dimensionally printed microfluidic devices and corresponding methods of manufacture. Optionally, the disclosed microfluidic devices can function as artificial lung devices.

The present invention includes: a first sealing portion which has a first entry/exit selectively opened or closed by a first opening/closing valve and a second entry/exit selectively opened or closed by a second opening/closing valve and is configured to seal one end of a housing; a second sealing portion which has a third entry/exit selectively opened or closed by a third opening/closing valve and a fourth entry/exit selectively opened or closed by a fourth opening/closing valve, and is configured to seal the other end of the housing; and a controller which is configured to control the supply of raw water through any one of the first entry/exit and the second entry/exit or control the supply of raw water through any one of the third entry/exit and the fourth entry/exit.

The present invention generally relates to a method of joining and sealing a vanadium based membrane to a metallic connection section. The invention is particularly applicable to joining a tubular vanadium or vanadium alloy membrane to a stainless steel body and it will be convenient to hereinafter disclose the invention in relation to that exemplary application. The present disclosure also includes methods of joining and sealing a vanadium based membrane to a metallic connection section.

A filter structure includes a housing having an inlet and an outlet; a first filter embedded in the housing and including a polymer membrane for filtering a first fluid flowing from the inlet into the housing; and a second filter embedded in the housing, filtering a second fluid filtered by the first filter, and including mesoporous silica nanoparticles (MSN).