Systems and methods can be used to produce fibers with external corrugations, internal corrugations, or both. These fibers can be used, for example, in hollow fiber membrane modules

Systems and methods can be used to produce fibers with external corrugations, internal corrugations, or both. These fibers can be used, for example, in hollow fiber membrane modules.

A hollow fibre membrane having a coiled, a hemihelix, a helical or an undulated native form, in which the membrane can be stretched by up to 4-times its original length with no plastic deformation, and wherein the native form of the membrane is produced by the asymmetric flow of liquid polymer through an opening of a die or nozzle.

Chromatography devices and methods for forming and using the devices are described. The devices include a polyimide-based support phase and a polymer grafted to a surface of the polyimide-based support phase. A microwave-assisted graft polymerization protocol is described to form the polymer at the surface of the support phase. Devices can be utilized in high-efficiency separation of macromolecules such as proteins.

A separation membrane has high strength and low leakage property while maintaining high gas permeability using poly(4-methyl-1-pentene) excellent in chemical resistance and gas permeability. The separation membrane contains poly(4-methyl-1-pentene) as a main component, in which a ratio RA of a rigid amorphous of poly(4-methyl-1-pentene) in the separation membrane is 43% or more and 60% or less, a porosity is 30% or more and 70% or less, and a dense layer is provided on at least one surface.

A hollow fiber membrane that is a hollow fiber type semipermeable membrane, wherein a Raman value is 70% or more, and the Raman value is a ratio of a minimum value to a maximum value of peak intensities, which are intensities of maximum peaks in each of multiple Raman spectra obtained by Raman spectroscopy at multiple points in a membrane thickness direction of a transverse cross-section of the hollow fiber membrane in a state of being swollen with water.

In embodiments of the present disclosure, a CMS hollow fiber membranes may be prepared to have an ultrathin (e.g. 2 microns or less) separation layer. A precursor hollow fiber may be prepared as dual layer fibers having a thin sheath layer and a core layer. During pyrolysis, the sheath layer is transformed into an ultrathin separation layer. Porosity of the core layer substrate is well-maintained during pyrolysis, thereby enabling high permeance of the CMS hollow fiber membrane. Additionally, in some embodiments, the sheath layer of the precursor hollow fibers may be hybridized prior to pyrolysis. By hybridizing the sheath layer prior to pyrolysis, a CMS hollow fiber may having an improved separation factor, including for example increased carbon dioxide/methane selectivity, may be provided.

A filament production device, in particular a filament reaction-spinning production device, comprising at least one spinning nozzle unit, which is provided for producing at least one filament formed as a hollow fibre membrane from at least one polymer solution, and comprising a polymerisation unit, which is provided for initiating a polymerisation of the polymer solution, wherein the polymerisation unit is provided for initiating the polymerisation at least partially within the spinning nozzle unit.

A roll-to-roll process and apparatus is disclosed for treatment of a membrane substrate. The apparatus and process processes the membrane substrate in a forward direction using one or more treatment solutions, and then processes the membrane substrate in a reverse direction using other treatment solutions. The treatment solutions used in the forward and reverse directions are preferably chosen so that the treatment sequence is the same in both directions. In this manner, the membrane substrate can accumulate reaction time by repeated processing in forward and reverse directions. t,?

The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.