The present invention relates to a continuous process for preparing permselective hollow fiber membranes being suitable e.g. for hemodialysis, hemodiafiltration and hemofiltration of blood which comprises a two-stage drying and tempering treatment of the hollow fiber membranes. According to a further aspect, the invention relates to a continuous process for drying permselective hollow fiber membranes on-line. The invention also relates to devices for on-line drying of permselective hollow fiber membranes.

The invention relates to a method for manufacturing a hollow fiber membrane bundle from a plurality of polysulfone and PVP-based hollow fiber membranes which encompasses the providing of a spinning solution comprising a polysulfone-based material, in particular polysulfone, a vinylpyrrolidone-based polymer, in particular polyvinylpyrrolidone, an aprotic solvent, in particular dimethylacetamide, providing a coagulant liquid comprising water and an aprotic solvent, in particular dimethylacetamide, co-extruding the spinning solution and the coagulant liquid through a concentric annular spinneret into a hollow strand, whereby the cavity of the strand is filled with coagulant liquid, conducting the strand through a precipitation gap, introducing the strand into a precipitating bath comprised substantially of water so as to obtain a hollow fiber membrane, conducting the hollow fiber membranes through at least one rinsing bath and drying the hollow fiber membrane obtained, arranging the resulting hollow fiber membranes into a hollow fiber membrane bundle, and treating the hollow fiber membrane bundle with water vapor.

The invention relates to hydrophobic hollow fiber membranes, and in particular, to hydrophobic organic-inorganic composite hollow fiber membranes. Methods for forming the hydrophobic organic-inorganic composite hollow fiber membranes are also disclosed. The hydrophobic organic-inorganic composite hollow fiber membranes may be used in membrane contactor applications such as gas-liquid (G-L) contactor and liquid-liquid (L-L) contactor processes. Applications for G-L membrane contactors include gas streams purification (gas absorption), water ozonation, and water deoxygenation. Applications for L-L membrane contactors include direct contact membrane distillation and liquid-liquid extraction.

Provided are a lined hollow fiber membrane (HFM) with a sandwich structure, and a preparation method and use thereof. In the lined HFM with a sandwich structure, a membrane structure of the lined HFM includes an inner PVDF layer, a braided liner layer, and an outer PVDF layer in sequence from inside to outside.

The present invention provides a porous hollow fiber membrane and methods of using the membrane to select an immune checkpoint inhibitor. The membrane can be used in animal models with an immune system and using a low-cost common mouse. The host immune system is unable to attack the cancer cells within the membrane and an animal study proves that the membrane system can be performed within animals.

A fiber membrane prepared based on in-situ growth and an application thereof in toluene adsorption are provided. A method for preparing a fiber membrane based on in-situ growth includes the following steps: (1) adding 2-aminoterephthalic acid and polyacrylonitrile (PAN) powder into a solvent, and mixing uniformly to obtain a spinning solution; (2) performing electrospinning on the spinning solution, and drying to obtain a fiber membrane; (3) placing the fiber membrane in an alcohol solution, adding ethylenediamine, and performing thermal crosslinking; after the thermal crosslinking, cleaning and drying to obtain a crosslinked fiber membrane; and (4) placing the crosslinked fiber membrane in a solvent, adding zirconium oxychloride, 2-aminoterephthalic acid, and benzoic acid, and performing in-situ growth to obtain a fiber membrane prepared based on in-situ growth. The fiber membrane prepared based on in-situ growth of the present disclosure has a large toluene adsorption capacity, which may be recycled and reused.

A hollow fiber membrane for separating blood plasma from blood, comprising a blood contact layer and a support layer each comprising a hydrophobic polymer, a hydrophilic polymer and vitamin E, and a method for producing said hollow fiber membrane to provide a hollow fiber membrane is described. The hollow fiber membrane is characterized by a reduced hemolysis activity so that the hollow fiber membrane can be advantageously used in plasmapheresis methods.

The present disclosure relates to a spinneret for producing hollow fiber membranes in a phase inversion process.

The present disclosure relates to a spinning beam for producing hollow fiber membranes in a phase inversion process, and to a process using the spinning beam.

Asymmetric hollow fiber membranes comprising a porous substrate layer and a skin layer are described. The skin layer is a copolymer of polymethyl pentene and polypropylene. Gas separation articles made using such hollow fiber membranes, as well as methods of making and using such hollow fiber membranes and gas separation articles are also described.