A filter module for sterile filtration and virus filtration of fluid media. The filter module includes a filter membrane with a porous edge structure arranged thereon and at least one anchoring element. The filter membrane with the porous edge structure is embedded in the anchoring element and serves as edge reinforcement to improve the connection of the filter membrane to the anchoring element. The texturing or surface roughness of the edge reinforcement provides an interlocking effect between the filter membrane and the anchoring element. The embedding of the filter membrane in the anchoring element provides a fluid-tight connection of the membrane to the anchoring element which prevents the occurrence of leaks in the end region of the filter module. A method for producing the filter module is also described.

A filter module for sterile filtration and virus filtration of fluid media. The filter module includes a filter membrane with a porous edge structure arranged thereon and at least one anchoring element. The filter membrane with the porous edge structure is embedded in the anchoring element and serves as edge reinforcement to improve the connection of the filter membrane to the anchoring element. The texturing or surface roughness of the edge reinforcement provides an interlocking effect between the filter membrane and the anchoring element. The embedding of the filter membrane in the anchoring element provides a fluid-tight connection of the membrane to the anchoring element which prevents the occurrence of leaks in the end region of the filter module. A method for producing the filter module is also described.

New carbon nanomaterials, preferably titanium carbide-derived carbon (CDC) nanoparticles, were embedded into a polyamide film to give CDC/polyamide mixed matrix membranes by the interfacial polymerization reaction of an aliphatic diamine, e.g., piperazine, and an activated aromatic dicarboxylate, e.g., isophthaloyl chloride, supported on a sulfone-containing polymer, e.g., polysulfone (PSF), layer, which is preferably previously prepared by dry/wet phase inversion. The inventive membranes can separate CO.sub.2 (or other gases) from mixtures of CO.sub.2 and further gases, esp. CH.sub.4, based upon the generally selective nanocomposite layer(s) of CDC/polyamide.

A water filtration membrane is provided, capable of removing heavy metal ions, filtering out particulates, filtering out bacteria, as well as removing herbicides and volatile organic compounds (VOCs) from water. The membrane is composed of a mat of randomly oriented nanoparticle-coated nanofibers. The nanofibers are covalently bonded to a plurality of substantially uniformly-distributed ceramic nanoparticles embedded in or adhered on the surface of the polymer nanofibers through reactive functional groups. The ceramic nanoparticles have a pattern of deep grooves formed on the nanoparticle surfaces. The bonding of the nanoparticles to the nanofibers is sufficient to retain the nanoparticles on the nanofiber surfaces when water flows through the water filtration membrane. The diameter of the nanofibers is 50-200 nm. The size of the nanoparticles is <40 nm, with a zeta potential of −40 to −45 mV in a dispersion medium. The nanoparticle deep grooves have an average size of approximately 1.2 nm or less.

A water filtration membrane is provided, capable of removing heavy metal ions, filtering out particulates, filtering out bacteria, as well as removing herbicides and volatile organic compounds (VOCs) from water. The membrane is composed of a mat of randomly oriented nanoparticle-coated nanofibers. The nanofibers are covalently bonded to a plurality of substantially uniformly-distributed ceramic nanoparticles embedded in or adhered on the surface of the polymer nanofibers through reactive functional groups. The ceramic nanoparticles have a pattern of deep grooves formed on the nanoparticle surfaces. The bonding of the nanoparticles to the nanofibers is sufficient to retain the nanoparticles on the nanofiber surfaces when water flows through the water filtration membrane. The diameter of the nanofibers is 50-200 nm. The size of the nanoparticles is <40 nm, with a zeta potential of −40 to −45 mV in a dispersion medium. The nanoparticle deep grooves have an average size of approximately 1.2 nm or less.

The invention relates generally to methods of improving function of a transplanted organ, treating or preventing primary graft dysfunction of a transplanted organ, treating or preventing acute rejection of a transplanted organ, treating or preventing delayed graft function, or achieving a clinical endpoint indicative of a successful organ transplant in a recipient of the transplanted organ which comprise contacting blood from the recipient with an extracorporeal membrane having a plurality of pores having an average pore size of at least 40 kDa, 50 kDa or 60 kDa to permit inflammatory cytokines and other inflammatory molecules to pass through the pores and out of the blood that is returned back to the recipient.

A process for the efficient transfer of molecules between phases employing mesoporous poly (aryl ether ketone) hollow fiber membranes is provided. The method addresses the controlled transfer of reactants into and removal of reaction products from a reaction media and the removal and separation of target molecules from process streams by membrane-assisted liquid-liquid extraction. A number of possible modes of liquid-liquid extraction are possible according to the invention by utilizing porous poly (aryl ether ketone) hollow fiber membranes of Janus-like structure that exhibit a combination of hydrophilic and hydrophobic surface characteristics. The method of the present invention can address the continuous manufacture of chemicals in membrane reactors and is useful for a broad range of separation applications, including separation and recovery of active pharmaceutical ingredients.

The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

The disclosed technology includes a membrane-based device configured to concentrate black liquor, which results from papermaking. Certain embodiments may comprise a nanofiltration membrane configured to remove lignin from black liquor, and the nanofiltration membrane may include a first macroporous polymer substrate and a first graphene oxide membrane covering the first macroporous polymer substrate. Some embodiments may comprise a reverse osmosis membrane, which may include a second macroporous polymer substrate and a second graphene oxide membrane covering the second macroporous polymer substrate.