A method for processing a fluid includes removably securing a retention member to a vessel that bounds a chamber; inserting a collapsible bag within the chamber of the vessel; securing the bag to the retention member so that the bag is supported within the chamber of the vessel; and dispensing a fluid into a compartment of the collapsible bag supported within the chamber of the vessel. The fluid can be mixed within bag while the bag is disposed within the vessel.

A system for performing a gas-liquid mass transfer includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween. A tube has a first end and an opposing second end, the first end of the tube being disposed within the compartment of the container. A nozzle is disposed within the compartment of the container and has at least one outlet, the nozzle being coupled with the tube so that a gas can be passed through the tube and out the at least one outlet of the nozzle. The nozzle is sufficiently buoyant so that when a fluid is disposed within the compartment of the container, the nozzle floats on the fluid.

Miniature stirred tank bioreactor and system; the bioreactor configured for single use culturing providing unobstructed culturing volume with sensors, probes and ports using minimally invasive placement in-wall or across the wall methods; the bioreactor further capable of containing scaffolds and features for culturing cells and tissue, including structures providing surfaces for cell growth, and screens for retaining microparticles during media exchange.

Miniature stirred tank bioreactor and system; the bioreactor configured for single use culturing providing unobstructed culturing volume with sensors, probes and ports using minimally invasive placement in-wall or across the wall methods; the bioreactor further capable of containing scaffolds and features for culturing cells and tissue, including structures providing surfaces for cell growth, and screens for retaining microparticles during media exchange.

Provided is a method of producing an ultrafine bubble-containing liquid containing ultrafine bubbles generated by causing film boiling in a liquid with a heat generation member, including: detaching a solid present at a liquid contact surface of the heat generation member in a form of a microscopic substance by using the film boiling; and generating ultrafine bubbles with the detached microscopic substance as a core.

The device (1) for bringing a gas and a liquid into contact includes an enclosure (E), first means (5) for introducing into the enclosure and circulating therein a gas stream (G), second means (6) for introducing into the enclosure and circulating therein a liquid stream (L) that circulates inside the enclosure (E) in the same direction as the gas stream (G), and means (4A) for mixing the gas stream (G) and the liquid stream (L). These mixing means (4A) are positioned inside the enclosure (E) in the path of the gas stream and liquid stream and are capable of locally deflecting upward, and/or of locally causing to rise, at least one portion of the gas stream and liquid stream, so as to locally create turbulences in the gas stream and in the liquid stream.

An aeration apparatus for aerating water discharged from a hydraulic turbine includes: a manifold disposed within a crown of a runner of the hydraulic turbine; a plurality of radial pipes extending radially from an outer perimeter of the manifold and in fluid communication with the manifold; and one or more air injectors having a first end disposed within an aeration pipe, each of the one or more air injectors having a second end extending into a nozzle at a first end of one of the radial pipes. Rotation of the aeration apparatus resulting from rotation of the runner causes pumping of water from the manifold through the radial pipes past the one or more air injectors, and water flowing past the one or more air injectors causes air to become entrained in the water. The radial pipes discharge the water and entrained air from the aeration apparatus.

An aeration apparatus for aerating water discharged from a hydraulic turbine includes: a manifold disposed within a crown of a runner of the hydraulic turbine; a plurality of radial pipes extending radially from an outer perimeter of the manifold and in fluid communication with the manifold; and one or more air injectors having a first end disposed within an aeration pipe, each of the one or more air injectors having a second end extending into a nozzle at a first end of one of the radial pipes. Rotation of the aeration apparatus resulting from rotation of the runner causes pumping of water from the manifold through the radial pipes past the one or more air injectors, and water flowing past the one or more air injectors causes air to become entrained in the water. The radial pipes discharge the water and entrained air from the aeration apparatus.

Provided are an immediately-before-stirring-type fluid processing device and an immediately-before-stirring-type fluid processing method that can adjust or improve the final properties of a fluid to be processed that is introduced as a raw material into an annular flow channel of a microreactor employing the annular flow channel, which is formed between relatively rotating processing surfaces, as a flow channel in which fluid processing is performed. A fluid to be processed, which has been prepared in a fluid preparing system so as to be in an ideal state for reaction, is charged into a fluid processing device. The fluid processing device subjects the fluid to be processed to reaction processing in an annular flow channel, which is formed between two processing surfaces. A cylindrical stirring space is provided in the radially inner side of the annular flow channel, and a rotor and a screen are disposed inside the stirring space. Stirring energy is applied by the rotor and a shearing force is applied between the rotor and the screen to the fluid to be processed immediately before the fluid to be processed is introduced into the annular flow channel.

A bioproduction mixing system includes a flexible compartment having a first end, a second end, and a sidewall extending therebetween, a center axis passing through the flexible compartment between the first end and the second end. A helical assembly is disposed within the flexible compartment and is suspended between the first end and the second end, the helical assembly being offset from the center axis of the flexible compartment.