A bioproduction mixing system includes a flexible compartment having a first end, a second end, and a sidewall extending therebetween, a center axis passing through the flexible compartment between the first end and the second end. A helical assembly is disposed within the flexible compartment and is suspended between the first end and the second end, the helical assembly being offset from the center axis of the flexible compartment.

A bubble formation apparatus (500) includes: a rotor (100); a container (200) in which the rotor (100) is housed together with a liquid (LQ) and a gas (GS); and a rotary device (300) that causes rotation of the rotor (100) with the rotor (100) being pressed against an inner lower surface (221) that is the inner surface of the container (200). A bubble is formed by periodically repeating pressurization and depressurization of a mixture of the gas (GS) and the liquid (LQ) in a gap between the inner lower surface (221) and a portion, pressed against the inner lower surface (221), of the rotor (100) due to the rotation of the rotor (100) by the rotary device (300).

A bubble formation apparatus (500) includes: a rotor (100); a container (200) in which the rotor (100) is housed together with a liquid (LQ) and a gas (GS); and a rotary device (300) that causes rotation of the rotor (100) with the rotor (100) being pressed against an inner lower surface (221) that is the inner surface of the container (200). A bubble is formed by periodically repeating pressurization and depressurization of a mixture of the gas (GS) and the liquid (LQ) in a gap between the inner lower surface (221) and a portion, pressed against the inner lower surface (221), of the rotor (100) due to the rotation of the rotor (100) by the rotary device (300).

Provided is a generating method for generating an ultra-fine bubble-containing liquid in which multiple types of UFB s of different gas components are mixed at a desired concentration ratio, and a manufacturing apparatus for a liquid containing ultra-fine bubbles. Multiple types of UFB-containing liquids are generated for each gas contained by the UFBs, and the UFB-containing liquids are mixed with each other based on a mix proportion of a desired UFB concentration.

A viscous fluid reaction apparatus is described. The viscous fluid reaction apparatus comprises a glass reaction vessel. The viscous fluid reaction apparatus further comprises a gas-tight inlet assembly and a gas-tight stirrer assembly. The gas-tight stirrer assembly comprises a stirrer opening adapter, a stirrer coupling comprising a stirrer shaft seal connected to the stirrer opening adapter, a stirrer shaft comprising one or more stirrer blades located at a blade end of the stirrer shaft, and a motor coupling connected to the stirrer shaft. The viscous fluid reaction apparatus further comprises a motor connected to the motor coupling. The stirrer shaft passes through the stirrer coupling and the stirrer opening adapter such that the stirrer blade(s) are disposed in the glass reaction vessel at a blade height and the stirrer shaft is configured to rotate without compromising a gas-tight seal formed by the stirrer shaft seal.

An apparatus for treating fluids such as waste streams with improved aeration efficiency and dual function operation has a blower-assisted aerator, an impeller, a baffle structure circumscribing an air line that includes a first baffle and a second perforated baffle downstream from the first baffle, and a liquid reservoir containing a liquid. The impeller is fully submerged, and located upstream of the fully submerged baffle structure. A fully submerged air outlet is located downstream of the baffle structure, preferably in close proximity to the perforated baffle. When the blower is stopped and the impeller rotating, the baffle structure prevents aspiration into the liquid. In some embodiments, the baffle structure is removably affixed to an air outlet from the blower-assisted aerator, and so may be applied to pre-existing blower-assisted aerators. In some embodiments, one or both of the first and second baffles may resemble flat, domed, cupped, or hemispherical washers.

A nano-bubble-generating apparatus includes: an elongate housing defining an interior cavity adapted for receiving a liquid carrier, a liquid inlet, and a liquid outlet; a gas-permeable member at least partially disposed within the interior cavity of the housing that includes a first end adapted for receiving a pressurized gas, a second end, and a porous sidewall; and an electrical conductor adapted to generate a magnetic flux parallel to an outer surface of the gas-permeable member as the liquid carrier flows from the liquid inlet to the liquid outlet. The housing and gas-permeable member are configured such that the flow rate of the liquid carrier flowing parallel to the outer surface of the gas-permeable member is greater than the turbulent threshold of the liquid to create turbulent flow conditions, thereby allowing the liquid to shear gas from the outer surface of the gas-permeable member and form nano-bubbles in the liquid carrier.

A nano-bubble-generating apparatus includes: an elongate housing defining an interior cavity adapted for receiving a liquid carrier, a liquid inlet, and a liquid outlet; a gas-permeable member at least partially disposed within the interior cavity of the housing that includes a first end adapted for receiving a pressurized gas, a second end, and a porous sidewall; and an electrical conductor adapted to generate a magnetic flux parallel to an outer surface of the gas-permeable member as the liquid carrier flows from the liquid inlet to the liquid outlet. The housing and gas-permeable member are configured such that the flow rate of the liquid carrier flowing parallel to the outer surface of the gas-permeable member is greater than the turbulent threshold of the liquid to create turbulent flow conditions, thereby allowing the liquid to shear gas from the outer surface of the gas-permeable member and form nano-bubbles in the liquid carrier.

A generating method for generating a UFB at a desired component ratio, and a manufacturing apparatus and a manufacturing method for a liquid containing a UFB at a desired component ratio are provided. To this end, a mixed solution in which multiple types of gases are dissolved at a predetermined ratio is generated, and a UFB is generated by heating the mixed solution with a heating element.

A method of installing a flexible bioprocess container in a bioprocessing system having a rigid housing with an interior compartment and extending between a top and an opposing base. The method includes coupling a first surface of the flexible bioprocess container to a moveable platform positioned within the interior compartment of the rigid housing; coupling a second surface of the flexible bioprocess container to the base of the rigid housing; and moving the movable platform relative to the rigid housing and toward the top of the rigid housing so as to at least partially expand the flexible bioprocess container within the interior compartment of the rigid housing.