An example system for conditioning drilling fluid includes a tank to hold drilling fluid and outlet conduits located at least partly within the tank. The outlet conduits have a tree structure that includes a trunk and branches. Each of the branches has one or more nozzles for outputting drilling fluid within the tank. The system also includes one or more inlet conduits for receiving drilling fluid from the tank and one or more pumps that are controllable to suction the drilling fluid from the tank through the one or more inlet conduits and to force the drilling fluid into the tank through the outlet conduits.

Devices, systems, and their methods of use, for generating and collecting droplets are provided. Devices use flow focusing arrangements of channels to produce droplets. The invention further provides multiplex devices that increase droplet formation.

An example system for conditioning drilling fluid includes a tank to hold drilling fluid and outlet conduits located at least partly within the tank. The outlet conduits have a tree structure that includes a trunk and branches. Each of the branches has one or more nozzles for outputting drilling fluid within the tank. The system also includes one or more inlet conduits for receiving drilling fluid from the tank and one or more pumps that are controllable to suction the drilling fluid from the tank through the one or more inlet conduits and to force the drilling fluid into the tank through the outlet conduits.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

The invention relates to a process for preparing a dispersion of a lipophilic compound in a continuous hydrophilic phase, the morphology of which is submicronic. During the preparation of this dispersion, there is applied, by means of a device which produces a shearing gradient less than 5000 s.sup.−1, a shear stress from 100 to 5000 Pa during the addition of the lipophilic compound in the continuous phase which comprises a rheology-modifying compound selected from anionic copolymers, preferably an anionic polymer, in particular an ASE polymer or a HASE polymer. The dispersed particles of the lipophilic compound are nanometric particles whose size is less than 1 μm. The dispersion, particularly in the form of an emulsion, can be used in numerous fields.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

A novel method for producing a heat stable oil-in-water emulsion for the formulation of cannabinoids in beverages. Such a method provides great utility to expand the types of cannabinoid containing products that may be produced, while ensuring manufacturers are not at risk of perceived under formulation. Known methods used to produce beverages containing cannabinoids, particularly cannabidiol (CBD), are insufficient or inadequate to withstand the high heat often encountered during shipping or storage. One such method of producing a heat stable cannabinoid beverage is presented along with a formulation using said method to produce a CBD energy shot beverage that has been proven to withstand temperatures of up to 45° C. for greater than 17 weeks.

Systems, methods, and devices for forming an array of emulsions. An exemplary device comprises a frame and at least one or a plurality of separate microfluidic modules mounted to the frame and each configured to form an array of emulsions. In some embodiments, each module may be mounted by snap-fit attachment. The device also may include the same sealing member bonded to a top side of each module and hermetically sealing each of the modules. Another exemplary microfluidic device for forming an array of emulsions comprises a stack of layers bonded together. The stack may comprise a port layer forming a plurality of ports. Each port may have a top rim formed by a protrusion that encircles the central axis of the port. The rims may be coplanar with one another to facilitate bonding of a sealing member to each rim.