A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.

A device for producing nanoparticles includes: a first connector comprising a first supply tube fitting member, a second supply tube fitting member, and a first discharge tube fitting member; a first tube having one side connected to the first supply tube fitting member; a second tube having one side connected to the second supply tube fitting member; a first conduit having one side connected to the first discharge tube fitting member; a first supply connected to another side of the first tube to supply a first material to the first conduit; and a second supply connected to another side of the second tube to supply a second material to the first conduit.

A static mixer for desalting a fluid is disclosed. A static mixer can include a housing, a reduction cone disposed concentrically within the housing; and an expansion cone disposed concentrically within the housing; wherein the static mixer is configured to direct fluid flow through the reduction cone onto the expansion cone, thereby mixing the fluid.

An automated drilling-fluid additive system and method for on-site real-time analysis and additive treatment of drilling fluid to be injected into a well. The drilling fluid includes returned drilling fluid intended to be re-used, which has a variety of viscosity and other qualities resulting from its various preceding use. The target drilling fluid will have a variety of viscosity and other qualities depending upon and changing with various phases of drilling operations and various conditions encountered. The drilling fluid is analyzed in real time as it flows into the automated drilling-fluid additive system, and various additives are added to and thoroughly blended with the drilling fluid as needed to achieve the desired result. The blended drilling fluid is discharged from the automated drilling-fluid additive system in the proper condition for injection into a well.

The invention involves the use of supercritical or near supercritical fluids to inactivate pathogens in biologic materials which may or may not be contaminated by pathogens. The pathogen reduced material is then inserted into empty, sterile containment vessels. The apparatus can be used as a means to achieve terminal sterilization of the biologic materials. The preferred method of use for the apparatus includes operation of a conveyor belt to move and fill bottles, flasks, containers, or vials in an assembly line to create the finished product in an effective and timely fashion.

The present disclosure includes mixing apparatuses comprising a first conduit defining an inlet channel, a second conduit defining an outlet channel, and an injection assembly that is disposed between the first and second conduits. The injection assembly can comprise two or more mixers, each having a reducer conduit that defines a mixing channel and an expander conduit that defines an expanding channel. The injection assembly can also comprise a first injection conduit configured to inject fluid into the mixing channel. At least one of the mixers can comprise a shut-off valve movable from an open position to a closed position in which the shut-off valve prevents fluid from flowing from the mixer to the second conduit. Closing the shut-off valve can increase the fluid flow rate in at least one other of the mixing channels.

A method as well as a liquid mixing system for providing a liquid mixture of water with at least one additive. The liquid mixing system comprises a first water reservoir, a first additive reservoir, a mixing unit, a conveying device and a line network. At least one first measurement value of the flow of the first additive conveyed to a mixing device is determined by an additive flowmeter. The total stream of the liquid mixture conveyed by the conveying device is measured by a liquid mixture flowmeter. The determined measurement values are transmitted to a control device, and from there passed on to a data storage device where they are stored.

This in-line active and reverse calculating mass balance blending system can maintain a chemical at desired control points, such as with respect to concentration, temperature, and/or pressure, while the output flow rate is changing dynamically to a point of use. A blending unit is configured to receive and blend at least two species and deliver a mixture at selected concentrations to points of use. A controller can be configured to determine a mass balance to maintain the concentrations in the mixture using information from metrology systems and a flow in an output to the at least one point of use. The controller also can be configured to maintain a concentrations in the mixture within a concentration range by controlling flow rates to the blending unit.

The production method of hot milk with or without froth, with a Venturi effect emulsifying device suitable for sending, into a mixing chamber, a flow of steam so as to aspirate, by Venturi effect, milk and air or only milk, comprises a production cycle of hot milk with froth and a production cycle of hot milk without froth being carried out by supplying an equal flow of steam of equal duration into a mixing chamber having equal volume, equal conformation and equal inlet section of the milk but a different outflow section of the milk.

This in-line active and reverse calculating mass balance blending system can maintain a chemical at desired control points, such as with respect to concentration, temperature, and/or pressure, while the output flow rate is changing dynamically to a point of use. A blending unit is configured to receive and blend at least two species and deliver a mixture at selected concentrations to points of use. A controller can be configured to determine a mass balance to maintain the concentrations in the mixture using information from metrology systems and a flow in an output to the at least one point of use. The controller also can be configured to maintain a concentration in the mixture within a concentration range by controlling flow rates to the blending unit.