A method of mixing a fluid includes at least partially unfolding a collapsible bag bounding a compartment, the collapsible bag containing in the compartment at least a portion of an elongated drive line or drive shaft and an impeller secured to the drive line or drive shaft, the impeller including a plurality of impeller blades that are pivotable relative to the drive line or drive shaft, at least one of the plurality of impeller blades being in a collapsed position. A fluid is delivered into the compartment of the collapsible bag. The drive line or drive shaft is then rotated so as to rotate the impeller within the compartment and mix the fluid therein, the at least one of the plurality of impeller blades pivoting from the collapsed position to an expanded position as the impeller is rotated within the compartment.

A dynamic mixer head has a cover, a housing, and a rotor. The cover has a first base board, two inlets, and a holding cylinder. A rotor holding channel is formed in the holding cylinder and a sealing portion protrudes from an inner wall surface of the rotor holding channel. The housing is mounted on the cover and has a second base board, a mixing cylinder, and an inner channel. The inner channel is formed in the mixing cylinder and fluidly communicates with an outlet. The rotor is rotatably disposed in the inner channel and has a rotor axle and a mixing rod. The rotor axle is disposed through the rotor holding channel, contacts and is surrounded by the sealing portion. The mixing rod has multiple first vanes. The dynamic mixer head does not need two sealing structures and tight fitting of the rotor and the holding cylinder.

The present set of embodiments relate to a system, method, and apparatus for culturing cells within a cell culture vessel having a mixing element. The cell culture system includes a flexible portion and a mixing element disposed therein. The mixing element includes a suspended foldable portion. The system is configured to reduce shear stress on cells without compromising mixing efficiency. This reduction is accomplished by using a mixing element having a large surface area allowing for reduced rotational speeds. The system is collapsible for ease of transport and disposal. The flexible portion collapses and the foldable portion folds to minimize the volume of the system while not in operation.

A feed stock-to-vermicast converter, comprising an enclosed flow-through vessel having an upstream inlet for introducing convertible feed stock into a mixed epigeic bed conversion zone adapted to accommodate a population of epigeic vermicast-producing worms, communicating with a vermicast-converted feed stock outlet.

A container for fermenting bio-degradable substances, the container comprising: a base and a wall, wherein an interior of the container is enclosed by the base and the wall; a rotatable agitator that protrudes into the interior and is supported in an upper bearing and a lower bearing in an installed position of the rotatable agitator in the container, wherein the rotatable agitator includes a shaft that is drivable by a drive, wherein at least one stirring paddle is arranged at the shaft and configured to co-rotate with the shaft so that substances arranged in the container are stirrable, wherein the lower bearing is arranged at the at least one base of the container and a bearing device located at a lower end of the shaft is supported in the lower bearing in the installed position of the rotatable agitator.

Provided is a continuous stirred tank reactor for an aldol condensation reaction and an apparatus for an aldol condensation reaction including the same, which prevent a decrease in a conversion rate due to dead zone occurrence even in the case of an increase of an installation scale, have a high output, have a significantly increased reaction surface area during the reaction, suppress layer separation between an aqueous phase and an organic phase, and have a significantly decreased average particle diameter of organic layer particles dispersed in the aqueous phase and a significantly decreased deviation thereof. In addition, a content of the catalyst used per unit yield may be significantly decreased as compared with the conventional reactor and apparatus, and costs required for wastewater treatment may be significantly reduced as compared with the conventional reactor and apparatus.

A method of mixing a fluid includes at least partially unfolding a collapsible bag bounding a compartment, the collapsible bag containing in the compartment at least a portion of an elongated drive line or drive shaft and an impeller secured to the drive line or drive shaft, the impeller including a plurality of impeller blades that are pivotable relative to the drive line or drive shaft, at least one of the plurality of impeller blades being in a collapsed position. A fluid is delivered into the compartment of the collapsible bag. The drive line or drive shaft is then rotated so as to rotate the impeller within the compartment and mix the fluid therein, the at least one of the plurality of impeller blades pivoting from the collapsed position to an expanded position as the impeller is rotated within the compartment.

This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals. In some embodiments, reactor systems comprising a mobile carriage assembly; a disposable reaction container removably attached to the carriage assembly; and, a carriage holder into which the mobile carriage assembly may be removably inserted are provided.

A method for connecting functional elements (14) to a shaft (10, having the following steps: (a) forming elevations (12) for receiving the functional elements (14), said elevations (12) being machined out of the shaft (10) by removing material, and (b) welding the functional elements (14) to the elevations (12) on the shaft (10).

A mixing blade includes a first end of the blade having a first face and a second end of the blade opposite the first end of the blade and having a second face. A first blade face and a second blade face are disposed between the first end and second end. A first end cap that has an outer face and an inner face with the inner face abutting the first face of the first end of the blade. A second end cap that has an outer face and an inner face with the inner face abutting the first face of the second end of the blade.