According to one embodiment, a fluid controller includes a fluid channel deforming portion and a mixing portion provided downstream from the fluid channel deforming portion. The fluid channel deforming portion includes an upstream end portion, a first channel, a second channel and a channel terminating portion. At least one of the first and second channels is deformed between the upstream end portion and the channel terminating portion. A region of the second channel in a second cross-section, is increased more than a region of the second channel in the first cross-section, between the upstream end portion ad the channel terminating portion. The mixing portion mixes a plurality of fluids flowing through the fluid channel deforming portion.

The present disclosure provides an apparatus for producing fine particles, the apparatus comprising: a particle formation mechanism and a particle-outlet micro-channel. The particle formation mechanism may include a unit-structure, wherein the unit-structure includes: first and second portions adjacent to each other; a first inlet defined in the first portion at a first height, wherein a continuous phase solution is injected into the first inlet; a second inlet defined in the first portion at a second height different from the second height, wherein a dispersed phase solution is injected into the second inlet; a merging volume defined in the second portion adjacent to the first portion, wherein the merging volume is defined at third height, wherein the third height is equal to either the first height and the second height, or has a value between the first height and the second height, wherein the continuous phase solution and the dispersed phase solution are merged in the merging volume, wherein fine particles are formed via the merging between the continuous phase solution and the dispersed phase solution in the merging volume; and a first micro-channel and a second micro-channel branching from the merging volume so as to be in communication with the first inlet and the second inlet, respectively.

A high volume microfluidic system for producing emulsions includes a fluid distribution network to produce uniformly sized emulsions and encapsulates.

Disclosed herein is a microfluidic mixer comprising first and second input chambers, first and second flow paths, and an output chamber. According to embodiments of the present disclosure, the first input chamber and the output chamber respectively have their bottom surfaces leveled with that of the first and/or second flow paths, while the second input chamber has its bottom surface protruded below that of the first flow path. Also disclosed herein is a microfluidic system comprising the present microfluidic mixer, and a pump for introducing a first and a second fluid reactants respectively into the first and a second input chambers.

Disclosed herein is a microfluidic mixer comprising first and second input chambers, first and second flow paths, and an output chamber. According to embodiments of the present disclosure, the first input chamber and the output chamber respectively have their bottom surfaces leveled with that of the first and/or second flow paths, while the second input chamber has its bottom surface protruded below that of the first flow path. Also disclosed herein is a microfluidic system comprising the present microfluidic mixer, and a pump for introducing a first and a second fluid reactants respectively into the first and a second input chambers.

A pipe welding structure includes: a channel plate that includes a fluid channel; through-hole plates stacked on the channel plate, each of the through-hole plates having through holes that communicate with each other and forming a combined through hole; and a pipe inserted into the combined through hole and welded to one of the through-hole plates disposed farthest from the channel plate, the pipe internally including a pipe channel that connects to the fluid channel.

The invention provides a microdroplet- or bubble-producing device that does not require separate through-holes for different liquid droplet/air bubble-producing flow channels. The droplet-producing flow channels are configured in a three-dimensional manner unlike in a conventional device where they are configured in a two-dimensional plane, and therefore the flow channels can be provided in a more high-density configuration than the prior art. In the microdroplet/bubble-producing device comprising slit(s) and the row of the plurality of microflow channels, the slit(s) is/are a continuous phase supply slit, a dispersion phase supply slit and a discharge slit, the plurality of microflow channels are configured so that the ends of the slit(s) and the two supply ports on both sides or the supply port and discharge port on either side are mutually connected, and at the sites of connection between the microflow channels and the slit(s), the dispersion phase undergoes shear with the continuous phase flow as the driving force, producing droplets or air bubbles of the dispersion phase, which are recovered from the discharge port.

The invention provides a microdroplet- or bubble-producing device that does not require separate through-holes for different liquid droplet/air bubble-producing flow channels. The droplet-producing flow channels are configured in a three-dimensional manner unlike in a conventional device where they are configured in a two-dimensional plane, and therefore the flow channels can be provided in a more high-density configuration than the prior art. In the microdroplet/bubble-producing device comprising slit(s) and the row of the plurality of microflow channels, the slit(s) is/are a continuous phase supply slit, a dispersion phase supply slit and a discharge slit, the plurality of microflow channels are configured so that the ends of the slit(s) and the two supply ports on both sides or the supply port and discharge port on either side are mutually connected, and at the sites of connection between the microflow channels and the slit(s), the dispersion phase undergoes shear with the continuous phase flow as the driving force, producing droplets or air bubbles of the dispersion phase, which are recovered from the discharge port.

A micro-reactor system for contacting fluids is described. The system comprises a first microfluidic channel structure for guiding a first fluid to at least one output nozzle thus generating a first sub-flow, a second microfluidic channel structure for guiding a second fluid to at least a second output nozzle thus generating a second sub-flow, said first output nozzle being aligned with said second output nozzle and arranged for contacting the first sub-flow and the second sub-flow. The micro-reactor comprises at least a third microfluidic channel structure for at least a third, inert, fluid generating at least a third sub-flow arranged to be positioned adjacent at least the first and/or the second sub-flows so as to act as a wall between said first and/or second sub-flows.

An example microfluidic mixer can include an inlet microfluidic channel portion and a fluid splitting channel portion including an overpass microfluidic channel to receive fluid from a first side of the inlet microfluidic channel portion and an underpass microfluidic channel to receive fluid from a second side of the inlet microfluidic channel portion, where the underpass microfluidic channel extends under the overpass microfluidic channel such that the channels overlap at their respective downstream ends. A fluid recombining channel portion is downstream of the fluid splitting portion and includes an angled recombining surface having an acute angle with respect to a direction of fluid flow, where the angled recombining surface is between the downstream ends of the overpass and underpass microfluidic channels. An outlet microfluidic channel portion is fluidly connected downstream from the fluid recombining channel portion.