A method for filtering a gas includes passing a gas into a compartment of a casing that includes a polymeric film, the casing having: a first sleeve having a first outlet opening, a first filter being at least partially disposed within the first sleeve so that gas passing through the first sleeve must pass through the first filter; and a second sleeve having an second outlet opening, a second filter being at least partially disposed within the second sleeve so that gas passing through the second sleeve must pass through the second filter, the second sleeve being closed so that the gas passing into the compartment of the casing passes through the first sleeve and the first filter and directly contacts at least a portion of the first sleeve comprised of the polymeric film but does not pass through the second sleeve. Opening the second sleeve when a predetermined condition is met so that the gas passes through the second sleeve and the second filter.

A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.

A filter assembly includes a casing having of a polymeric film and bounding a compartment, the casing having an inlet opening communicating with the compartment and a first outlet opening communicating with the compartment. A first filter includes a porous filter body through which gas can pass and has a pore size smaller than 1 m, the first filter being coupled with the casing so that the filter body is at least partially disposed within compartment of the casing and so that gas passing through the compartment of the casing from the inlet opening to the first outlet opening must pass through the filter body.

Miniature stirred tank bioreactor and system; the bioreactor configured for single use culturing providing unobstructed culturing volume with sensors, probes and ports using minimally invasive placement in-wall or across the wall methods; the bioreactor further capable of containing scaffolds and features for culturing cells and tissue, including structures providing surfaces for cell growth, and screens for retaining microparticles during media exchange.

The invention relates to a diffusor for adding of gases into water, said diffusor comprising a perforated tube (1) and at least one supply tube (2), said the at least one supply tube (2) is at one end coupled to a source for supplying gas and at the other end in fluid communication with the perforated tube (1), the gas is supplied to the perforated tube (1) through at least one inner supply tube (4; 5; 15) extending from the supply tube (2) to the perforated tube (1). The invention is distinctive in that at the least one inner supply tube (4; 5; 15) is a non-perforating tube and has at least one outlet (4a, 5a, 15a) situated at a free end of the at least one inner supply tube (4, 5, 15), said gas is adapted to be distributed into the perforated tube (1) through the at least one outlet (4a, 5a, 15a).

A flow-type carbonization device includes: a first pipe, in which beverage to be carbonized and carbon dioxide flows and a second pipe, in which beverage to not to be carbonized flows. At least one turbulence generation element is arranged in the first pipe. The first and second pipes are in thermal communication such that heat from a fluid flowing in the second pipe heats the first pipe for sterilizing the first pipe. In one embodiment, the first and second pipe are arranged concentrically.

Miniature stirred tank bioreactor and system; the bioreactor configured for single use culturing, providing unobstructed culturing volume with sensors, probes and ports using minimally invasive placement in-wall or across the wall methods; the bioreactor further capable of containing scaffolds and features for culturing cells and tissue, including structures providing surfaces for cell growth, and screens for retaining microparticles during media exchange

A method of mixing a pharmaceutical solution including adding a gas into an interior compartment of a mix bag to form a headspace. The interior compartment of the mix bag includes a top portion and a bottom portion. The headspace adjacent to the top portion contains gas. The method includes adding a solvent into the mix bag, and establishing a bubble column in the interior compartment by activating a recirculation assembly. The recirculation assembly includes a connecting pathway operably coupled to a recirculation pump. A first end of the connecting pathway is coupled to a top gas recirculation port and a second end is coupled to a bottom gas recirculation port of the mix bag such that the recirculation pump draws the gas from the headspace and delivers the gas to the interior compartment via the bottom gas recirculation port. The method includes adding a solute into the mix bag.

A device for producing a bone cement dough from a monomer liquid and a cement powder and dispensing the bone cement dough. The device includes a cartridge holding the cement powder in an internal space. A monomer receptacle screws onto the cartridge, forms a chamber, and has a plunger with a passage that is permeable to gases and the monomer liquid but is impermeable to the cement powder and that connects the internal space to the chamber. The plunger tightly closes the internal space with the exception of the passage. A gas supply opening is arranged in the wall of the monomer receptacle. A monomer liquid container holds the monomer liquid and is located in the chamber. An opening facility opens the container, and closes the gas supply opening before opening the container. Also provided is a method for producing and dispensing the bone cement dough.

An assembly is provided. The assembly comprises a single-use sterilizable bag for containing a biological material, wherein the single-use sterilizable bag comprises at least one insertion opening; and at least one insertable component configured to be inserted into the single-use sterilizable bag via the at least one insertion opening, wherein the at least one insertable component comprises: a positioning unit for positioning the insertable component with respect to the single-use sterilizable bag; and at least one of a processing unit and a sensing unit for handling the biological material.