A storage and mixing device for two-component polymethyl methacrylate bone cements having a cylindrical interior of a cartridge that is delimited on a front side by a cartridge head, a plunger arranged to be axially movable in the cylindrical interior of the cartridge and spaced from the cartridge head, a powdery first parent component of the bone cement, that is contained in the interior between the plunger and the cartridge head, a feed-through arranged in the cartridge head or in the cylinder barrel of the cartridge between the plunger and the cartridge head. The feed-through is connectable to a fluid line, a receptacle for a monomer liquid, wherein the fluid line connects the feed-through to the receptacle in a liquid-permeable manner, and a press-out device pushable into the receptacle, so that monomer liquid is pressable out of the receptacle into the fluid line. The plunger (2) is spaced from a back side of the cylindrical interior, located opposite the front side, so that, by moving the plunger in the direction of the back side, the press-out device is pushable into the receptacle and a reduced pressure is producible in the interior of the cartridge between the plunger and the cartridge head.

A storage and mixing device for PMMA bone cements having a cylindrical interior of the cartridge that is delimited on a front side by a cartridge head with a closed delivery opening, a plunger which is arranged to be axially movable in the cylindrical interior of the cartridge and which is spaced from the cartridge head. The plunger circumferentially rests against the inner wall of the interior, so that the plunger divides the interior of the cartridge into two sections in a gas-tight manner, a powdery first parent component of the bone cement, which is contained in the interior between the plunger and the cartridge head, a feed-through which is arranged in the cartridge head or in the cylinder barrel of the cartridge between the plunger and the cartridge head, wherein the feed-through is connected to a fluid line in which a monomer liquid as a second parent component of the bone cement is contained or into which a monomer liquid is fillable or introducible. A filter is arrangeable in the cartridge head, in the feed-through and/or in the fluid line, wherein the filter is permeable to the monomer liquid and impermeable to the first parent component, wherein the plunger is spaced from a back side of the cylindrical interior, located opposite the front side, to an extent that, by moving the plunger in the direction of the back side, a reduced pressure is producible in the interior of the cartridge between the plunger and the cartridge head, wherein the reduced pressure is able to suck the monomer liquid out of the fluid line into the interior of the cartridge.

A mixer gun system includes a holder cap configured to separately store components in separate chambers. The components are selectively releasable through channels fluidly communicating with the separate chambers. The components are constituent materials for a bone cement mixture. A body forms a mixing chamber and is configured to receive the holder cap. The mixing chamber includes an opening corresponding with the channels for the separate chambers. A piston is disposed within the mixing chamber. A plunger is coupled to the piston and is configured to be biased toward the mixing chamber such that when the components are released into the mixing chamber a pressure developed by a biased motion of the plunger and piston infuses the components to form bone cement. Upon resetting the plunger and the piston, the bone cement is dispensed from the mixing chamber by the same biased motion. Methods of use are disclosed.

One aspect relates to a device for providing a bone cement from two starting components, having a hollow cylinder-shaped first container, in which a monomer liquid as first starting component can be stored, a hollow cylinder-shaped second container comprising a container wall, a first internal space, and a second internal space, whereby a bone cement powder as second starting component can be stored in the first internal space, and whereby the monomer liquid can be conveyed into the second internal space, a fluid-conducting conveying means arranged between the first internal space and the second internal space, whereby the first container and the second container are axially connected to each other.

A mixing method using a manufacturing apparatus having a mixing machine having a support defining a receiving housing including a first and a second receiving locations configured to receive a first and a second deformable capsules, respectively, the first and second capsules configured to be fluidly linked and containing respectively a first and a second formulations, an actuation system configured to transmit a pressure force to the first and second capsules to move the content of the first capsule in the second capsule, and vice versa, the mixing machine includes a heater element configured to heat at least one of the first and second capsules when received in the mixing machine, the method includes: Heating and/or kneading having, alternately or simultaneously, setting in motion of the actuation system and heating by the heater element up to a target temperature; then cooling with kneading through setting in motion of the actuation system from which the kneading is stopped.

A mixing method using a manufacturing apparatus having a mixing machine having a support defining a receiving housing including a first and a second receiving locations configured to receive a first and a second deformable capsules, respectively, the first and second capsules configured to be fluidly linked and containing respectively a first and a second formulations and a second formulation,

an actuation system configured to transmit a pressure force to the first and second capsules to move the content of the first capsule in the second capsule, and vice versa,

the mixing machine includes a heater element configured to heat at least one of the first and second capsules when received in the mixing machine,

the method includes heating and/or kneading, alternately or simultaneously, setting in motion of the actuation system and heating by the heater element, and

maintaining a withdrawal temperature by the heater element, without motion of the actuation system.

A manufacturing apparatus includes a mixing machine having a receiving housing with a first receiving location configured to receive a first deformable capsule and a second receiving location configured to receive a second deformable capsule, the first and second capsules intended to be fluidly linked to each other and containing respectively a first formulation and a second formulation.

The mixing machine has at least an electrically motorized actuation system configured to transmit a pressure force to the first and second capsules to move the content of the first capsule in the second capsule, and vice versa, and an electrical heater element configured to heat at least one of the first and second capsules when the first and second capsules are received in the mixing machine, in which, in a preparation phase prior to bringing the two formulations into contact, the actuation system and the heater element are electrically supplied alternately.

A mixing machine, configured to receive a receiving device in order to form a mixing machine includes a support defining a receiving housing, able to receive a receiving device, the receiving device being configured to receive first and second capsules containing respectively a first formulation and a second formulation, the two capsules being fluidly linked to each other, an actuation system, movable inside the receiving housing to exert a pressure force on the receiving device and/or on the first and/or the second capsule(s), and a coupling mechanism, movable relative to the support and configured: in an insertion position, not to interfere with the insertion and the withdrawal of the receiving device into/from the receiving housing, and in a coupling position, to exert a force on an actuation face of the receiving device.

An apparatus for manufacturing a cosmetic product including a mixing machine having a removable receiving device, a support defining a receiving housing, able to receive the receiving device, the receiving device being configured to receive first and second capsules containing respectively a first formulation and a second formulation, the two capsules being fluidly linked to each other, an actuation system, movable inside the receiving housing to exert a pressure force on the receiving device and/or on the first and/or the second capsule(s), a clamping mechanism, movable relative to the support and configured:
in an insertion position, not to interfere with the insertion and the withdrawal of the receiving device including capsules into/from the receiving housing, and
in a clamping position, to pinch a section of a capsule,
in which the clamping mechanism is a clamping wheel, movable in rotation about a clamping wheel axis.

A receiving device to form a manufacturing apparatus when the receiving device is inserted into a mixing machine, includes a first receiving location configured to receive a first capsule containing a first formulation, a second receiving location configured to receive a second capsule containing a second formulation, a first bearing element located at the level of a first actuation face of the receiving device and movable inside the first receiving location, to exert a force on the first capsule, and/or a second bearing element located at the level of a second actuation face, preferably opposite to the first actuation face, and movable inside the second receiving location, in order to exert a force on the second capsule,
wherein at least one bearing element is a vane movable in rotation about a hinge, the movable vane being configured to enter one of the first and second receiving locations.