According to one example, a valve for an apparatus configured to mix bone cement is disclosed. The valve can include a base defining a first portion of a passage. The passage can be configured to allow a component of the bone cement through the valve. The valve can include a projection extending from the base to a base opposing end and forming a second portion of the passage that communicates with the first portion. The projection can have a frustoconically shaped surface that comprises one of an outer surface or an inner surface that forms a part of the second portion of the passage.

A fluidic centripetal apparatus for testing components of a biological material in a fluid is presented. The fluidic centripetal device is adapted to be received within a rotatable holder. The apparatus comprises a fluidic component layer having fluidic features on at least a front face and a bottom component layer bonded to a rear of the fluidic component layer thereby creating a fluidic network through which the fluid flows under centripetal force. In one embodiment, the fluidic feature may be a bottom-fillable chamber coupled to an entry channel for receiving the fluid, the chamber inlet being provided at an outer side of the bottom-fillable chamber. In another embodiment, the fluidic feature may be a retention chamber coupled to an entry channel for receiving the fluid, a container wholly provided in the retention chamber and containing a liquid diluent, the container maintaining the liquid diluent in the container until it releases it in the retention chamber upon application of an external force to the container, thereby restoring the fluidic connection between the liquid diluent and the fluid in the retention chamber. Additionally, the retention chamber can have a flow decoupling receptacle for receiving the fluid, located at the outer side of the retention chamber and interrupting a fluidic connection between the entry and exit of the retention chamber. A test apparatus and a testing method using a fluidic centripetal device for testing components of a biological material in a fluid are also provided.

A carbonated beverage maker includes a water reservoir, a carbon dioxide creation chamber, and a carbonation chamber. The water reservoir holds ice water and has a first impeller and a shroud surrounding the first impeller. The carbon dioxide creation chamber contains chemical elements and receives warm water. The chemical elements react with each other to create carbon dioxide when the warm water is introduced to the carbon dioxide creation chamber. The carbonation chamber is connected to the water reservoir and the carbon dioxide creation chamber. The carbonation chamber has a second impeller that includes a stem portion and blades. The stem portion and the blades define conduits therein. The blades create a low pressure region in a lower portion of the carbonation chamber such that carbon dioxide from the carbon dioxide creation chamber flows through the conduits to the low pressure region.

A dissolving and mixing unit for automatically dissolving and mixing medicines includes: a support; a dissolving and mixing device mounted on the support and including two piercer bases and at least one dissolving and mixing channel, wherein each dissolving and mixing channel includes two piercers and an elastic infusion hose connecting the two piercers, and the two piercers of each dissolving and mixing channel are mounted on the two piercer bases respectively; a peristaltic pump mounted on the support and configured to squeeze the elastic infusion hose; first and second bottle-containing modules mounted on the support and configured to hold first and second medicine containers respectively; and a movement mechanism configured to drive at least one of the first bottle-containing module and one piercer base to move, and configured to drive at least one of the second bottle-containing module and the other piercer base to move.

A system for mixing a sample with a combined buffer includes a sampler body, the sampler body including a first reservoir and a second reservoir. The system further includes a first separator forming a first enclosure with the sampler body for the first reservoir. The system further includes a second separator forming a second enclosure with the sampler body for the first reservoir. The system further includes a third separator, in conjunction with the second separator, forming a third enclosure and a fourth enclosure, respectively, both in conjunction with the sampler body, for the second reservoir.

A capsule for mixing multiple substances, comprising: a main chamber having a main chamber bottom and a main chamber top opening; at least two repository tubular chambers, each: adapted to contain substance, mechanically connected to the main chamber and having a repository tubular chamber top opening; at least two passages, each fluidly connecting one of the at least two repository tubular chambers to the main chamber; a main piston fitted in the main chamber; and a mixer rod having a mixer element disposed at a distal end and a torque adapter disposed at a proximal end for transferring a torque to the mixer element, the mixer rod is fitted to pass along the main piston such that the mixer element is mounted in the main chamber between the main chamber bottom and a distal end of the main piston when the main piston is in the outward position.

A liquid concentrate generation system may comprise a manifold having an inlet receptacle including a first piercing member, an outlet receptacle including a second piercing member, and a flow channel connecting the inlet receptacle and outlet receptacle. The system may further comprise a cartridge having an inlet port and an outlet port sealed by a respective first and second cover. The inlet and outlet port may be respectively configured to displace within the inlet receptacle and outlet receptacle from an unspiked position to a spiked position. First and second piercing members may be in communication with the flow channel and spaced apart respectively from the first and second cover in the unspiked position. The first and second piercing members may be isolated from the flow channel and may respectively puncture the first and second cover in the spiked position.

An adapter having a female coupling configured to receive and establish a friction seal with a male coupling of an external device for inserting or extracting a liquid to or from a container, by applying a load to the male coupling after inserting it into the female coupling, the load being provided by the weight of a portion of the external device, the adapter being configured for insertion in a mouth of the container and secured therein using a stretchable membrane that fits snugly around the mouth of the container for obtaining a tight seal, the stretchable membrane having tabs for a user to grasp.

The presently disclosed subject matter is directed to a device for dispensing a mixture of a first composition (e.g., an anesthetic) and a second composition (e.g., a diluent buffer, a second drug, or a solution). The device comprises a plunger that slidably engages with the interior of the device barrel at a first end. The second end of the device barrel includes a flexible container configured to house one or more solutions (e.g., sodium carbonate). The flexible container comprises a membrane positioned adjacent to the interior of the barrel. The flexible container can be manipulated by the user, rupturing the membrane. In this way, the first and second solutions are intermixed within the interior of the barrel, and can be administered to a patient.

A storage and mixing system, for pasty two-component polymethyl methacrylate bone cements, comprises a cartridge with a cylindrical interior, a cartridge head that closes an end of said cartridge, a partition wall axially disposed in the cylindrical interior of the cartridge, wherein said partition wall is connected to the circumferential surface of the cylindrical interior of the cartridge and divides the cylindrical interior of the cartridge delimited by the cartridge head into two spatially separate cavities. The first cavity includes a first pasty cement component and the separate second cavity includes a second pasty cement component, two delivery plungers close the two cavities on the side of the cavities opposite the cartridge head. At least two cutting edges are disposed on the front side of the sleeve-shaped connecting means facing the cartridge head, such that the at least two cutting edges cut off the partition wall from the cylindrical inner wall of the cartridge as at least one cut-off strip when the delivery plungers are advanced towards the cartridge head in the cavities with the connecting means, and wherein the sleeve-shaped connecting means comprises a deflecting surface which is inclined to the axis of the connecting means which, on advancing the connecting means, presses the at least one cut-off strip of the partition wall towards the inner wall of the cartridge.