An additive delivery system may incorporate a cartridge system, including a container cap and a reservoir assembly that provides for storage of an additive. The container cap includes a mixing nozzle for mixing of the additive with a base fluid as the base fluid flows from the base fluid container through the cartridge. A one-way valve prevents backflow of base fluid and/or mixed base fluid/additive from an area downstream of the mixing nozzle such that the base fluid supply remains in a pure state.

Embodiments of the present disclosure generally relate to systems and methods for mixing pharmaceutical compositions, agents and/or ingredients together. In one embodiment, a method can include a shell and a flexible pouch disposed within the shell. The flexible pouch can include at least one active pharmaceutical ingredient and at least one delivery agent. Further, the flexible pouch and the shell can be configured to receive a dispensing member for dispensing a predetermined amount of a pharmaceutical composition. Methods can also include subjecting the container to high intensity vibrations for a predetermined mixing time to produce the pharmaceutical composition.

Magnetic stir bar having at least one permanent magnet to spin the magnetic stir bar when the magnetic stir bar is subjected to a rotating magnetic field. The magnetic stir bar has a chamber to store a product within the magnetic stir bar. The magnetic stir bar has a closed configuration in which the chamber is closed and an open configuration in which the chamber is open. The magnetic stir bar automatically reconfigures itself from the closed configuration to the open configuration when said magnetic stir bar is spun at or above a threshold rotational speed.

A combination plunger, a mixing device and a mixing syringe including the same are provided. The mixing syringe includes concentric outer and inner barrels that form an outer chamber, the inner barrel having an inner chamber. The combination plunger includes a mixing plunger and a delivery plunger and a biasing means. The mixing plunger is slidably located in the outer chamber and translated by coordinated depression of the delivery plunger to transfer a first substance from the outer chamber to mix with a second substance in the inner chamber. After the mixing stage is complete, the delivery plunger is disengaged from the mixing plunger and permitted, such as by rotation, to be further depressed in the axial direction to deliver fluid contents of the mixing syringe to a recipient. The mixing syringe needle is then retracted as result of engagement by the delivery plunger and activation of the biasing means.

A liquid dispensing system comprises a container enclosing a chamber. A flexible bag in the chamber contains a first liquid. First and second conduits are contained in the chamber. The first conduit connects the chamber to an outlet port in the container were the second conduit connects the bag to the first conduit. A supply source introduces a pressurized second liquid into the chamber. The first conduit serves to direct an exiting flow of the second liquid from the chamber to the outlet port, with the pressurized second liquid serving to collapse the bag and expel the first liquid contained therein via the second conduit to the first conduit for mixture with the exiting flow of the second liquid. The second conduit lacks flow restrictions, such as metering orifices or the like.

An improved applicator and a method for applying two or more components which can be mixed together. They are intended to effectively prevent unintentional and unintentional mixing of the components at the discharge orifices and any associated uncontrolled or undesirable reaction of the components with each other during downtime of the applicator. The applicator/application device (1) for the application of at least two components can be mixed with one another, comprising coaxially arranged one within the other component feeds (2, 3) with the component feeds (2a, 3a) for the respective at least two components and component discharge orifices (2b, 3b) associated with the component feeds (2, 3),

An additive delivery system may incorporate a cartridge system, including a container cap and a reservoir assembly that provides for storage of an additive. The container cap includes a mixing nozzle for mixing of the additive with a base fluid as the base fluid flows from the base fluid container through the cartridge. A one-way valve prevents backflow of base fluid and/or mixed base fluid/additive from an area downstream of the mixing nozzle such that the base fluid supply remains in a pure state.

A refillable solution dispensing device includes a housing having an upper section and a lower section. An actuator exposed through the exterior of the upper section. The actuator is movably connected to an air chamber and a solution chamber. The solution chamber is in fluid communication with the solution reservoir and a discharge nozzle. The air chamber is fluidly connected to the discharge nozzle. The actuator is coupled to a mixing shaft that protrudes into the lower section. The lower section comprises an interior volume that functions as a solution reservoir. A solution cartridge and water are inserted into the solution reservoir. A solution mixer is rotatably coupled to the mixing shaft combining the solution within the solution cartridge, the solution cartridge, and the water into one solution. Upon an activation of the actuator, the solution and the air will mix and exit the discharge nozzle.

Disclosed herein is an apparatus for promoting a mass transfer reaction. The apparatus comprises a flow distributor and a drive unit. The flow distributor has a top end surface, a bottom end surface and a peripheral surface that are axisymmetric with respect to a rotation axis. The flow distributor is configured to submerge in a fluid medium and to generate a flow of the fluid medium through at least one of the top end surface and the bottom end surface and through the peripheral surface by rotating around the rotation axis. The drive unit is configured to move the flow distributor perpendicular to the rotation axis.

A liquid dispensing system comprises a container enclosing a chamber. A flexible bag in the chamber contains a first liquid. First and second conduits are contained in the chamber. The first conduit connects the chamber to an outlet port in the container where the second conduit connects the bag to the first conduit. A supply source introduces a pressurized second liquid into the chamber. The first conduit serves to direct an existing flow of the second liquid from the chamber to the outlet port, with the pressurized second liquid serving to collapse the bag and expel the first liquid contained therein via the second conduit to the first conduit for mixture with the exiting flow of the second liquid. The second conduit lacks flow restrictions, such as metering orifices or the like.