A solids charging containment apparatus and method for mixing a solvent with a dry powder, comprising a dual compartment isolator for safely removing the dry powder from a dry powder container, a mixing vessel, and a negative cascading pressure controller. The dual compartment isolator comprises a staging compartment, a charging compartment and a raw material entry port, which is connected to the staging compartment and configured to isolate the dry powder container from the surrounding atmosphere. The mixing vessel includes a mixing chamber and a solids charging port fluidly connecting the mixing chamber to a containment valve in the charging compartment of the dual compartment isolator. The negative cascading pressure controller generates negative pressure in both the staging compartment and the charging compartment. The containment apparatus and method may be used to produce a slurry or solution mixture of solvent and dry powder during drug processing.

A main extruder and a side arm extruder are used in the extrusion of plastics with small amounts of additives or other small substances to be admixed. A minor portion of the plastic material is premixed with small quantity additive substances in a side arm extruder. The premixed material is discharged from the side arm extruder into the main extruder and there mixed with a major portion of feed material.

A facial pack manufacturing apparatus capable of discharging a mixture without a remnant, according to the present invention, comprises a main body formed with an injection hole into which a raw material of a facial pack and a solid agent are injected; a mixing unit for mixing the raw material and the solid agent introduced into the injection hole of the main body, and discharging the mixture; and a pack manufacturing unit for receiving the mixture discharged from the mixing unit and manufacturing the mixture into a facial pack, wherein the mixing unit includes: an upper body including a blade protruding downward so as to be rotatable; a lower body coupled to a lower portion of the upper body so that an upper side thereof is opened to insert the blade, and having a discharge unit through which the mixture is discharged and a through hole passing through the discharge unit; and an opening and closing unit, provided in the through hole so as to be vertically movable, for opening and closing the discharge unit.

A mixing device includes a container for receiving mixing material, with an emptying opening being arranged in the bottom thereof, and a closure cover for closing the emptying opening. The mixing device includes an emptying opening that can be easily and space-savingly opened and closed. The closure cover includes two closure cover portions which can be reciprocated relative to each other between a closed position in which the two closure cover portions are in contact with each other and together form the closure cover and an opened position in which the two closure cover portions are spaced from each other so that an opening is formed between the two closure cover portions for removal of the mixing material from the container.

A buffer management system includes at least one workstation configured to support a supply of concentrated buffer solution and an inline dilution skid having a manifold. The manifold is in fluid communication with the supply of concentrated buffer solution and is adapted to be placed in fluid communication with a source of water for injection (WFI). The manifold includes a buffer inlet line in selective fluid communication with the supply of concentrated buffer solution, a WFI inlet line in selective fluid communication with the source of WFI, and a discharge line in fluid communication with both the buffer inlet line and the WFI inlet line. The inline dilution skid is configured to variably mix the supply of concentrated buffer solution and the source of WFI to obtain a range of diluted buffer solutions.

A mixing device includes a mixing container for receiving mixing material and a mixer cover, wherein a first seal and a second seal is provided between the mixing container and the mixer cover. The first seal and the second seal are so arranged that a first air space is formed between the first seal and the second seal.

The invention provides a carbonation tank assembly for admixing a gas and a potable liquid used in preparation of drinks. The assembly includes a tank body with an interior that can be easily accessed for cleaning and repair purposes by removing upper and lower end plates securely and sealing fitted by gaskets to the upper and lower ends of the tank. The interior is connected to a liquid source for supplying liquid, a gas source for carbonating the liquid, and drawing means for dispensing carbonated liquid from the interior of the tank.

The present invention is an integrated at least two component system and method which combines at least two or more components and creates at least one new mixture. This system contains at least one first component in a first, optionally sealed, container and at least one second component in a second sealed container that is contained in or adjacent to the first container. Both components can be in a single container sealed off from each other. This system enables the mixing of these components to produce a new mixture, and then enables the application of this new mixture to be applied on at least one surface

A chemical dispenser for a chemical dispensing system is disclosed. The chemical dispenser includes an input selector valve having an opened position and a closed position and configured to be coupled to a diluent source, a diverter valve coupled to the input selector valve, and a plurality of eductors coupled to the diverter valve. The diverter valve includes a valve head having a diluent port, a valve seat having a plurality of eductor ports, wherein each eductor port is in communication with a respective one of the plurality of eductors, and a drive mechanism coupled to the valve head and configured to move the valve head relative to the valve seat. The valve head may include one or more pressure relief ports for equalizing the diluent pressure across the valve head. A chemical dispensing system including the chemical dispenser and a method of using the chemical dispenser are also disclosed.

A dynamic mixer dispense valve and metering apparatus suitable for use in mixing and applying high viscosity, disparate viscosity, high ratio and/or relatively immiscible two part compounds that exhibit short cure times includes a housing supporting a pair of valve assemblies each coupled to respective sources of base and accelerator components. A pair of pneumatic valve actuator s control the operation of the valve assemblies to control the flow of components into a mixing chamber. Within the mixing chamber a mixer impeller is rotatably supported and coupled to a source of rotational power. An additional pneumatic valve actuator combination operates a further flow control to prevent undesired material loss following a shot cycle.