Bubble column reactor assemblies are provided, an assembly (100) comprising: a reactor vessel (102) comprising a bottom end and a top end. A pre-distributor plate (114) having a bottom surface and a top surface, disposed in the 5 reactor vessel (102) such that the bottom surface faces the bottom end of the reactor vessel (102). A gas distributor (106) is disposed below the pre-distributor plate (114) to receive and inject gas into a liquid prior to distribution of gas and liquid by the pre-distributor plate (114). The gas distributor (106) comprises: a common manifold (108) and a plurality of ring-shaped pipes disposed along a length of the 10 common manifold (108); and a plurality of nozzles disposed along an outer circumference of each ring-shaped pipe of the plurality of ring-shaped pipes to inject gas and create vortexes for uniform distribution of the gas in the liquid.

A method and device for building an oligonucleotide on a solid phase resin within a filter reactor, wherein the method and device as used as a solid phase synthesis system. As part of the solid phase synthesis process, a protecting group will be removed from the 5′ position of an oligonucleotide that is attached to the solid phase resin and then an activated amidite (phosphoamidite) solution is added. The activated amidite solution flows up and down, or fluidizes and mixes with the resin beads within the bed reactor and reacts at the 5′ position of the oligonucleotide, wherein the phosphorous linkage found within the amidite comprises a P atom that is in an oxidation state of III. Once the activated amidite solution has been reacted, the P atom is converted from an oxidation state of III to an oxidation state of V. Any of the reactions including deblocking, coupling, oxidation, sulfurization, or capping can be fluidized or mixed to get complete contacting between the reagents and the resin. Reagents drain from the reactor out the filter bottom before washing. The resin bed is flat and channel free because of the fluidization or mixing prior to the washes and can be re-fluidized during any of the washes. A spray cone or other distributor evenly spreads reagents or wash solvents onto the top of the resin bed without disrupting the flat even spread of resin in the radial direction. Washing after any given reaction can be divided into several individual segments. The cleaner portion of washes after a particular reaction in one cycle, can be collected in a holding vessel and used as the first washes after reaction in the next cycle. In-process integrated multi-pass washing can be used to enable more efficient use of the wash solvent. Excess reagent solution used for deblocking reaction is recycled and reused from one phosphoramidite cycle to the next, making the use of deblocking more efficient.

A method of operating a gas-solid fluidized bed (130) is provided. The method comprises: flowing a pulsating gas flow upwards through a bed of solid particles from a distributor (104) to cause a dynamically structured bubble flow (130; and processing particles using the fluidized bed.

A method of operating a gas-solid fluidized bed (130) is provided. The method comprises: flowing a pulsating gas flow upwards through a bed of solid particles from a distributor (104) to cause a dynamically structured bubble flow (130; and processing particles using the fluidized bed.

The invention is directed to a process to continuously react a gaseous mixture of an epoxide compound and carbon dioxide in the presence of a heterogeneous catalyst at a pressure of between 0.1 and 0.4 MPa in one or more reactors to a liquid cyclic carbonate product and a gaseous effluent stream comprising unreacted epoxide compound and carbon dioxide. Part of the gaseous effluent is purged from the process and another part of the gaseous effluent is fed to an ejector where the gaseous effluent mixes with gaseous mixture of epoxide compound and carbon dioxide having a pressure which is at least more than 0.3 MPa higher than the pressure of the gaseous effluent. The obtained ejector effluent is fed to the one or more reactors.

The invention is directed to a process to continuously react a gaseous mixture of an epoxide compound and carbon dioxide in the presence of a heterogeneous catalyst at a pressure of between 0.1 and 0.4 MPa in one or more reactors to a liquid cyclic carbonate product and a gaseous effluent stream comprising unreacted epoxide compound and carbon dioxide. Part of the gaseous effluent is purged from the process and another part of the gaseous effluent is fed to an ejector where the gaseous effluent mixes with gaseous mixture of epoxide compound and carbon dioxide having a pressure which is at least more than 0.3 MPa higher than the pressure of the gaseous effluent. The obtained ejector effluent is fed to the one or more reactors.

Disclosed are a reaction tower, a production system, and a production method for producing potassium manganate. The reaction tower includes a reaction tower body and a bubble generator. The reaction tower body has a reaction chamber. The bubble generator includes an outer housing. The outer housing is disposed in the reaction chamber and has a gas flow channel therein. The outer housing is configured to direct an external reactant gas into the gas flow channel. The outer housing is provided with multiple first pores each having a diameter less than 10 mm, via which the gas flow channel communicates with the reaction chamber. The reaction tower is used in the production system. The reactant gas is introduced into the reaction chamber in the form of small bubbles by the action of the bubble generator, to increase the area of contact of the reactant gas with manganese ore powder and lye.

Disclosed are a reaction tower, a production system, and a production method for producing potassium manganate. The reaction tower includes a reaction tower body and a bubble generator. The reaction tower body has a reaction chamber. The bubble generator includes an outer housing. The outer housing is disposed in the reaction chamber and has a gas flow channel therein. The outer housing is configured to direct an external reactant gas into the gas flow channel. The outer housing is provided with multiple first pores each having a diameter less than 10 mm, via which the gas flow channel communicates with the reaction chamber. The reaction tower is used in the production system. The reactant gas is introduced into the reaction chamber in the form of small bubbles by the action of the bubble generator, to increase the area of contact of the reactant gas with manganese ore powder and lye.

A method for producing acrylonitrile, having: a catalyst treatment step of preparing a composite metal oxide catalyst including molybdenum, bismuth, and iron and including 50 ppm or more of carbon; and a vapor-phase catalytic oxidation step of subjecting propylene to ammoxidation reaction using the composite metal oxide catalyst to produce acrylonitrile.

A method for producing acrylonitrile, having: a catalyst treatment step of preparing a composite metal oxide catalyst including molybdenum, bismuth, and iron and including 50 ppm or more of carbon; and a vapor-phase catalytic oxidation step of subjecting propylene to ammoxidation reaction using the composite metal oxide catalyst to produce acrylonitrile.