A method of preparing a fire extinguishing core-shell microcapsule by a one-pot oil-in-oil/ water emulsion technique. The method includes dissolving a fluid fluoroketone or hydrofluorocarbon fire extinguishing core material and a polymer shell material into a volatile solvent to form a composite mixture. The composite solution is emulsified into a polar phase and a non-polar phase by adjusting a concentration of a surfactant or via mechanical agitation to provide interfacial tension tuning. The volatile solvent is evaporated to precipitate a microcapsule having a fire extinguishing material core and a polymer shell. In a further aspect, the method includes incorporating the core-shell microcapsules in a polymer matrix.

A composition comprising an emulsion comprising a plurality of particles is provided. An article comprising a substrate, and a plurality of particles comprising a core and a shell, wherein the plurality of particles are in the form of a coating layer on the substrate is provided. Further, a method for coating a substrate, and a method for preparing the composition are provided.

A solvent removing apparatus includes a container containing an emulsion comprising a first raw material of a continuous phase and a second raw material of a dispersed phase, an impeller rotating in the container to stir the emulsion, and a foam breaker spaced apart from the impeller on an upper portion of the impeller, positioned below a surface of the emulsion to be submerged in the emulsion when the emulsion is calm, and rotating to reduce foam generated during stirring of the emulsion.

A solvent removing apparatus includes a container containing an emulsion comprising a first raw material of a continuous phase and a second raw material of a dispersed phase, an impeller rotating in the container to stir the emulsion, and a foam breaker spaced apart from the impeller on an upper portion of the impeller, positioned below a surface of the emulsion to be submerged in the emulsion when the emulsion is calm, and rotating to reduce foam generated during stirring of the emulsion.

Disclosed is a controllable method for preparing phospholipid micelles, including: S1, preparing small phospholipid vesicles; S2, preparing a graphene thin-layer electrode substrate, S3, incubating, and S4, electroforming phospholipid micelles. According to the present application, lamellar graphene is used as the electrode substrate according to the present application, where a phospholipid bilayer film is firstly spread on the surface of the substrate, and phospholipid micelles are controlled in terms of formation as well as formation state by a certain alternating current electric field on the surface of graphene; the developed method of the present application is unique in design, simple in operation, and has the advantages of fast formation, short preparation cycle and good controllability.

It is an object of the present invention to provide a Janus nanoparticle, into which a drug can be encapsulated by a simple method, and a method for producing the same. According to the present invention, provided is a method for producing a Janus nanoparticle having a particle diameter of 0.01 to 5000 μm, which is composed of a lipid and a polymer, wherein the method comprises: a step of emulsifying a solution of one or more types of lipids and one or more types of polymers dissolved in a common solvent in an aqueous solution of a surfactant(s); and a step of removing the common solvent from the obtained emulsion.

Encapsulated solids are made by first encapsulating precursor materials in a polymer shell. The precursors are some combination of solids, liquids, gases, and/or gels. The precursors are then transformed into solids by emplacement of the capsule in an environment where gas or fluid transport into or out of the polymer shell causes transformation into solids.

Encapsulated solids are made by first encapsulating precursor materials in a polymer shell. The precursors are some combination of solids, liquids, gases, and/or gels. The precursors are then transformed into solids by emplacement of the capsule in an environment where gas or fluid transport into or out of the polymer shell causes transformation into solids.

The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

A method for nanoencapsulation of an amine adduct in a polymeric shell includes steps of emulsifying a first aqueous solution including the amine adduct into an organic solution including an organic solvent and a polymer to obtain a primary emulsion; emulsifying the primary emulsion into a second aqueous phase including a stabilizer to obtain a secondary emulsion; removing the organic solvent by evaporation to form solid nanocapsules; and separating the formed solid nanocapsules by centrifugation. The nanocapsules have an average size of between about 30 nm and about 597 nm.