A microchannel device, including a homogenization chamber, a deceleration-cooling channel, an acidity regulation channel, a microchannel reaction chamber, and an ultrafiltration desalination chamber. A method for preparing high-oil-load microcapsules using the aforementioned microchannel device, including: preparing an aqueous phase and an oil phase; feeding the aqueous phase and the oil phase to the homogenization chamber to form a first emulsion; cooling the first emulsion; adjusting pH of the first emulsion with dilute hydrochloric acid; feeding the first emulsion to the microchannel reaction chamber to form a second emulsion with a core-shell structure; removing Na.sup.+ and Cl.sup.− from the second emulsion; and subjecting the second emulsion to spray drying to obtain the high-oil-load microcapsule powder.

The wet adhesion of a coating composition may be improved through the use of voided latex particles as opacifying agents which contain a hollow interior as well as an outer shell of a polymer containing functional groups such as amino, 1,3-diketo, urea or ureido. Other types of functional groups may be introduced to the outer shell polymer in order to vary other desired characteristics of the coating. The voided latex particles are non-film-forming.

Methods of forming hollow nanoparticles, methods of making templates for use in forming hollow nanoparticles, templates made by such methods, and hollow nanoparticles formed by such methods and templates.

Provided herein is a nanopore structure, which in one aspect is a “carbon nanotube porin”, that comprises a short nanotube with an associated lipid coating. Also disclosed are compositions and methods enabling the preparation of such nanotube/lipid complexes. Further disclosed is a method for therapeutics delivery that involves a drug delivery agent comprising a liposome with a NT loaded with a therapeutic agent, introducing the therapeutic agent into a cell or a tissue or an organism; and subsequent release of the therapeutic agents into a cell.

The present invention relates to a process for producing microparticles laden with at least one active, wherein the microparticles are formed from a thermoplastic organic, polymeric material and in the unladen state, in their interior, have at least one cavity connected via pores to the surface of the microparticles, wherein (a) a composition of unladen microparticles are impregnated with a liquid comprising the active, whereby laden microparticles are obtained, which contain in the interior cavity the liquid, and (b) subjecting the laden microparticles to thermal treatment by passing a stream of free flowing laden microparticles in a carrier gas through a heated zone at a temperature of at least 20 K, in particular at least 40 K, e.g. 20 to 250 K especially 40 to 200 K above the softening temperature of the thermoplastic organic polymeric material, where the average residence time of the laden microparticles in the heated zone is not more than 60 s, in particular not more than 30 s, especially not more than 20 s or not more than 10 s, e.g. in the range of 0.1 to 60 s, in particular in the range of 0.1 to 30 s, more particularly in the range of 0.5 to 20 s and especially in the range of 1 to 10 s. The present invention further relates to compositions of microparticles filled with at least one active, in particular with at least volatile organic active, which is obtainable by a process of the invention, and to the use thereof, especially in a product selected from perfumes, washing and cleaning compositions, cosmetic compositions, personal care compositions, hygiene articles, foods, food supplements, fragrance dispensers and fragrances. The present invention further relates to products comprising an inventive composition of microparticles filled with at least one active, in particular with at least one volatile organic active, and to the use thereof, especially for controlled release of actives of low molecular weight and specifically for controlled release of aroma chemicals.

The invention relates to a microcapsule comprising a hollow or porous core, the hollow or porous core being composed of a crosslinked polymeric material and containing a component to be released, a shell, the shell being composed of a polymeric material containing a component, which is able to produce gas upon exposure to acid. The microcapsule can be used for formulating dental materials.

Disclosed herein are methods for preparing sporopollenin exine capsules (SECs) and methods for preparing composite materials that comprise SECs that utilize ionic liquid compositions. The composite materials typically include structural polymers and the SECs, and the SECs optionally may encapsulate useful materials, such as flame retardant materials, phase change materials, and therapeutic materials, such as probiotics and prebiotics. The composite materials may be prepared from ionic liquid compositions comprising the structural polymers and the SECs which optionally may encapsulate the useful materials, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials comprising the SECs. The composite materials may be used in applications include (1) wound dressings to cool down damaged tissue; (2) as textiles to regulate the body temperature; (3) in building materials to regulate building temperature; (3) to provide fire retardation in textile and building materials; and (4) to deliver and protect probiotics and prebiotics from acidic conditions and digestive enzymes in the stomach, so that they fully retain their biological activity in the guts.

The wet adhesion of a coating composition may be improved through the use of voided latex particles as opacifying agents which contain a hollow interior as well as an outer shell of a polymer containing functional groups such as amino, 1,3-diketo, urea or ureido. Other types of functional groups may be introduced to the outer shell polymer in order to vary other desired characteristics of the coating. The voided latex particles are non-film-forming.

A fluid storage media includes a plurality of microspheres. Each microsphere includes a porous core with a porous core material and having an exterior surface. A stored fluid is within the porous core. A coating layer covers all of the exterior surface of the porous core. The coating layer includes a coating material which transitions from a first state to a second state, wherein in the first state the coating material is permeable to the stored fluid, and in the second state the material is impermeable to the stored fluid. The coating material in the second state is configured to encapsulate and maintain the stored fluid inside the porous core. A method of making a fluid storage media, a method of delivering a fluid and a method of delivering a biologically active fluid medication to a patient are also disclosed.

Systems, methods, and compositions provided herein relate to preparation of beads encapsulating biomolecules for performing sequential reactions on the biomolecules. Some embodiments include preparation of nucleic acid reactions within the bead, wherein the bead includes pores that allow diffusion of molecules into or out of the beads while retaining other molecules of interest.