An aspect of the disclosure relates to a dialysate regenerator for connecting to a dialysis apparatus, the dialysate regenerator including a regenerator inlet for receiving dialysate; a regenerator outlet for dispensing regenerated dialysate; a hydraulic circuit connected between the regenerator inlet and the regenerator outlet, and further including a fluid portioning system to divide a dialysate flow into uniform portions for sequential regeneration An aspect of the disclosure relates to a dialysis system including a dialysis apparatus including: a fresh dialysate input; a spent dialysate output; and the dialysate regenerator, wherein the regenerator inlet may be coupled to the spent dialysate output for receiving spent dialysate, and wherein the regenerator outlet may be coupled to the fresh dialysate input for dispensing regenerated dialysate.

The invention relates to a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a soluble source of sodium ions. The sorbent comprises an ion exchange system which converts urea to ammonium ions and which is configured to exchange ammonium ions for predominantly hydrogen ions and to exchange Ca, Mg, and K for predominantly sodium ions. The soluble source of sodium ions overcomes an initial drop in sodium concentration in regenerated dialysate. When used in conjunction with an infusion system configured to utilise exchange of Ca, Mg and K for sodium during dialysate regeneration a desired sodium ion concentration can be maintained.

The invention relates to a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a soluble source of sodium ions. The sorbent comprises an ion exchange system which converts urea to ammonium ions and which is configured to exchange ammonium ions for predominantly hydrogen ions and to exchange Ca, Mg, and K for predominantly sodium ions. The soluble source of sodium ions overcomes an initial drop in sodium concentration in regenerated dialysate. When used in conjunction with an infusion system configured to utilise exchange of Ca, Mg and K for sodium during dialysate regeneration a desired sodium ion concentration can be maintained.

An ion exchanger includes a housing, a tube member, and an ion exchange resin. The housing includes an inlet port and an outlet port. The tube member is arranged inside the housing. The ion exchange resin is arranged between the tube member and the housing. A first flow passage and a second flow passage are formed in the housing. The first flow passage is configured to cause the coolant that has flowed in through the inlet port to flow directly to the outlet port. The second flow passage is configured to cause the coolant that has flowed in through the inlet port and passed through the ion exchange resin to flow to the outlet port. The first flow passage and the second flow passage are formed to join together in a state of being oriented in a same direction toward the outlet port.

An ion exchanger includes a housing, a tube member, and an ion exchange resin. The housing includes an inlet port and an outlet port. The tube member is arranged inside the housing. The ion exchange resin is arranged between the tube member and the housing. A first flow passage and a second flow passage are formed in the housing. The first flow passage is configured to cause the coolant that has flowed in through the inlet port to flow directly to the outlet port. The second flow passage is configured to cause the coolant that has flowed in through the inlet port and passed through the ion exchange resin to flow to the outlet port. The first flow passage and the second flow passage are formed to join together in a state of being oriented in a same direction toward the outlet port.

Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H.sup.+ZP within a casing for a treatment; and after the treatment, refurbishing the H.sup.+ZP while maintained within the casing via (i) regenerating the non-disinfected H.sup.+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H.sup.+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H.sup.+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H.sup.+ZP while maintained within the casing. Multiple batch sorbent refurbishing implementations are also disclosed.

Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H.sup.+ZP within a casing for a treatment; and after the treatment, refurbishing the H.sup.+ZP while maintained within the casing via (i) regenerating the non-disinfected H.sup.+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H.sup.+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H.sup.+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H.sup.+ZP while maintained within the casing. Multiple batch sorbent refurbishing implementations are also disclosed.

A device for purifying drinking water in multiple stages by combining orthogonal purification technologies in one module is described, where the device comprises a housing, a water inlet opening, a water outlet opening, a hollow cylinder which is filled with activated carbon, and a hollow cylinder with a semipermeable wall, wherein the hollow cylinder contains a chelating bactericidal gel or a chelating and bactericidal gel for removing heavy metals or bacteria or for removing heavy metals and bacteria.

A nanocomposite composition for controlling water hardness and a method of producing the nanocomposite, is disclosed. The nanocomposite composition comprises a plurality of semi-interpenetrating polymer network/zeolite-silver nanocomposite, including a polymer matrix. The polymer matrix is dispersed with a plurality of zeolite nanoparticles and a plurality of silver nanoparticles. The method of producing semi-interpenetrating polymer networks/zeolite-silver nanocomposite as hydrogel form comprises microemulsion polymerization of monomeric mixture uses methyl methacrylate (MMA) in presence of ethylene glycol dimethacrylate (EGDM) cross-linker for MMA monomer, acrylamide (AAm), acrylic acid (AAc) and linear poly vinyl alcohol (PVA) monomers in the presence of N,N′-methylene bisacrylamide (MBA) cross-linker and TX-100 surfactant. Further, the prepared nanocomposite is a water hardness removal filter and an efficient inhibition of sulfate-reducing bacteria nanocomposite. Also, the water filter cartridge exhibits a stable filtration performance during large scale production with reduced fluctuation infiltration flow rate and shows highly stable behaviors in high salt concentration.

A nanocomposite composition for controlling water hardness and a method of producing the nanocomposite, is disclosed. The nanocomposite composition comprises a plurality of semi-interpenetrating polymer network/zeolite-silver nanocomposite, including a polymer matrix. The polymer matrix is dispersed with a plurality of zeolite nanoparticles and a plurality of silver nanoparticles. The method of producing semi-interpenetrating polymer networks/zeolite-silver nanocomposite as hydrogel form comprises microemulsion polymerization of monomeric mixture uses methyl methacrylate (MMA) in presence of ethylene glycol dimethacrylate (EGDM) cross-linker for MMA monomer, acrylamide (AAm), acrylic acid (AAc) and linear poly vinyl alcohol (PVA) monomers in the presence of N,N′-methylene bisacrylamide (MBA) cross-linker and TX-100 surfactant. Further, the prepared nanocomposite is a water hardness removal filter and an efficient inhibition of sulfate-reducing bacteria nanocomposite. Also, the water filter cartridge exhibits a stable filtration performance during large scale production with reduced fluctuation infiltration flow rate and shows highly stable behaviors in high salt concentration.