Provided herein are monoliths with attached recognition compounds which selectively bind ligands, methods of preparing such monoliths, arrays thereof and uses thereof. For example, monoliths provide herein can be used in columns and arrays thereof.

Disclosed is a method for carrying out a chemical reaction in a reactor, at least one substance is present in a container that is closed in a gas-tight manner, is introduced into the reactor in said container and is released by breaking open the container. The container is designed such that it breaks open when a specified bursting pressure difference between the internal pressure and external pressure is exceeded. The container is broken open and the substance located in the container is thus released as a result of deliberate application in the reactor of a pressure difference exceeding the bursting pressure difference.

The invention generally relates to methods for quantifying an amount of enzyme molecules. Systems and methods of the invention are provided for measuring an amount of target by forming a plurality of fluid partitions, a subset of which include the target, performing an enzyme-catalyzed reaction in the subset, and detecting the number of partitions in the subset. The amount of target can be determined based on the detected number.

Embodiments of the present disclosure provide for -AApeptides, -AApeptide building blocks, methods of making -AApeptides and libraries of -AApeptides, methods of screening the -AApeptide libraries for desired peptidomimetic activity, and the like. The present disclosure also provides for -AApeptides that are inhibitors of A peptide aggregation, methods of inhibiting and disassembling A peptide aggregation, methods of inhibiting the toxicity of A aggregates towards N2a neuroblasotma cells, as well as methods and compounds for treating Alzheimer's disease.

The present invention generally relates to droplet libraries and to systems and methods for the formation of libraries of droplets. The present invention also relates to methods utilizing these droplet libraries in various biological, chemical, or diagnostic assays.

The invention generally relates to methods for quantifying an amount of enzyme molecules. Systems and methods of the invention are provided for measuring an amount of target by forming a plurality of fluid partitions, a subset of which include the target, performing an enzyme-catalyzed reaction in the subset, and detecting the number of partitions in the subset. The amount of target can be determined based on the detected number.