The present invention relates to a method for controlling an ultrafast chemical reaction using a microfluidic reactor, and more specifically, the present invention relates to a method for controlling an ultrafast chemical reaction such as the Fries rearrangement reaction and the like by using a microfluidic reactor by the 3D metal printing technique.

A method for synthesising metal oxide nanoparticles. The method comprises mixing, to provide a reaction mixture, a precursor solution comprising metal ions with an initiator solution to initiate a nanoparticle precipitation process, and then quenching the precipitation process by adding a quenching agent to the reaction mixture so as to yield a dispersion comprising metal oxide nanoparticles. The resulting metal oxide nanoparticles may have an average diameter of less than 7 nm, for example 5 nm or less.

Disclosed herein are methods for preparing nanomaterials, such as nanoparticles. The methods can involve jet-mixing two or more precursor solutions to form the nanomaterials. By rapidly mixing the precursor solutions, nanomaterials of improved quality and uniformity can be prepared in high yield (e.g., in yields of at least 85%). The methods are also scalable, and allow for the continuous production of nanomaterials. Also provided are jet-mixing reactors that can be used to prepare nanomaterials using the methods described herein.

A system for producing catalytically treated pyrolytic vapor.The system comprises a pyrolysis reactor (100) configured to produce pyrolytic vapor and a catalytic reactor (200) limiting abed area (B) into which a fluidized catalyst bed is configured to form in use. The catalytic reactor (200) comprises a static mixer (300) configured to spread the particulate catalyst within the bed area (B). Thus, the catalytic reactor (200) is configured to produce a mixture of the particulate catalyst and the catalytically treated pyrolytic vapor from the pyrolytic vapor. A method for producing catalytically treated pyrolytic vapor. The method comprises producing pyrolytic vapor and allowing at least a clean part of the pyrolytic vapor to chemically react in the presence of the particulate catalyst to produce a mixture of the particulate catalyst and catalytically treated pyrolytic vapor. The method comprises mixing, in the bed area, the pyrolytic vapor and the particulate catalyst with a static mixer.

In the present invention, a fluid handling device has: a first substrate made of resin whereon a channel is formed in a first surface; a first film made of resin and joined to the first surface of the first substrate; a second film made of resin a first surface of which is joined to a second surface of the first substrate; and a second substrate made of resin and joined to a second surface of the second film. A recessed part overlapping the channel in a plane view is formed on the surface of the second substrate joined to the second film. The glass transition temperature Tg.sub.1s of the first substrate, the glass transition temperature Tg.sub.1f of the first film, the glass transition temperature Tg.sub.2s of the second substrate, and the glass transition temperature Tg.sub.2f of the second film satisfy Tg.sub.1s, Tg.sub.2s>Tg.sub.1f, Tg.sub.2f.

Fluidic systems and methods in which oscillatory flow is employed are generally described. In some instances, one or more solenoids are used to drive the oscillation of a magnetically-susceptible body which creates oscillatory flow of a fluid in a fluidic channel in fluid communication with a channel containing the magnetically-susceptible body.

The present invention relates to a microfluidic or millifluidic device (1) comprising: —a support (2) made at least partially of a dielectric material, the support (2) comprising a first inlet (21a) adapted to be connected to a first reservoir containing gas, a second inlet (21b) adapted to be connected to a second reservoir containing liquid, an outlet (22) adapted to be connected to a receiver container containing gas and/or liquid, and a main microchannel or millichannel (3) present in the dielectric material allowing the liquid and the gas to flow from the inlets towards the outlet, —one or several ground electrode(s) (4) embedded in said dielectric material and extending along the main microchannel or millichannel (3), and —one or several high-voltage electrode(s) (5) embedded in said dielectric material and extending along the main microchannel or millichannel (3), wherein the high-voltage electrode(s) (5) and the ground electrode(s) (4) are located on opposite sides of the main microchannel or millichannel (3) so as to be able to generate an electric field inside the main microchannel or millichannel (3). The present invention relates also to a method for generating a plasma in a continuous manner using such a microfluidic or millifluidic device (1).

An apparatus for mass producing monodisperse microbubbles contains a microfluidic flow focusing device. The microfluidic flow focusing device includes a dispersed phase fluid supply channel having an outlet that discharges into a flow focusing junction, a continuous phase fluid supply channel having an outlet that discharges into the flow focusing junction, and a bubble formation channel having an inlet disposed at the flow focusing junction. The configuration of the flow focusing junction is such that, in operation, a flow of dispersed phase fluid discharging from the outlet of the dispersed phase fluid supply channel is engageable in co-flow by a focusing flow of continuous phase fluid discharging from the outlet of the at least one continuous phase fluid supply channel under formation of a gradually thinning jet of dispersed phase fluid that extends into the inlet of the bubble formation channel.

Disclosed herein is a device and method for changing the conditions of a solution flowing in a serial path. In particular, disclosed herein is a device that includes a chemical reactor, a first system, and a second system that are each serial to one another. Each of the first system and the second system include a mixing chamber, a solvent reservoir, a solvent pump, and one or more detectors. Also disclosed herein is a method for changing the condition of a solution that includes flowing a liquid sample in a path, serially mixing the sample with at least two discrete solvents while it flows through the path, and detecting the condition of the sample after it is mixed with each solvent.

The invention relates to a microfluidic system based on active control of flow resistance and balancing pressures in microfluidic channels and an improved method for enhancing reactions with magnetic beads used in disposable microfluidic devices and cartridges for use in, but not limited to, in-vitro diagnostics. The microfluidic system and device of the invention does not utilize mechanical moving parts to control the fluid flow and has no external fluidic connection to the instrument or fluidics controller. The microfluidic system and device combines magnetic control over the movement of magnetic detection beads with electric field and convective enhancement of the movement of analytes and/or or reagentss surrounding the magnetic detection beads, thereby enabling movement of magnetic beads and analytes in the same direction or in different directions. The present invention thereby provides significantly enhanced interactions between analytes and/or reagents with the magnetic beads, which yields higher sensitivity for detection.